Terpinen-4-ol Induces Ferroptosis of Glioma Cells via Downregulating JUN Proto-Oncogene

Single-cell spatial immune landscapes of primary and metastatic brain tumours

(2023) Elham Karimi et al.   NATURE

RING Finger Protein 10 Regulates AP-1/Meox2 to Mediate Pirarubicin-Induced Cardiomyocyte Apoptosis

(2023) Hongwei Shi et al.   Oxidative Medicine and Cellular Longevity

TFR2 regulates ferroptosis and enhances temozolomide chemo-sensitization in gliomas

(2023) Shiao Tong et al.   EXPERIMENTAL CELL RESEARCH

Glioblastoma and Other Primary Brain Malignancies in Adults

(2023) Lauren R. Schaff et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis

(2023) Abdel Jelil Njouendou et al.   Molecular Cancer

Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma

(2023) Jiayang Cai et al.   Cell Death & Disease

Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

(2023) Pavan S. Upadhyayula et al.   Nature Communications

Targeting NQO1/GPX4-mediated ferroptosis by plumbagin suppresses in vitro and in vivo glioma growth

(2022) Sheng Zhan et al.   BRITISH JOURNAL OF CANCER

Deoxyelephantopin and Its Isomer Isodeoxyelephantopin: Anti-Cancer Natural Products with Multiple Modes of Action

(2022) Tahir Mehmood et al.   MOLECULES

Aloe vera and Fermented Extracts Exhibit an Anti-Inflammatory Effect on Human Glioblastoma/Astrocytoma U373 MG Cells

(2022) Antonio Tornero-Martínez et al.   PLANT FOODS FOR HUMAN NUTRITION

JUN and PDGFRA as Crucial Candidate Genes for Childhood Autism Spectrum Disorder

(2022) Heli Li et al.   Frontiers in Neuroinformatics

Terpinen-4-ol inhibits the proliferation and mobility of pancreatic cancer cells by downregulating Rho-associated coiled-coil containing protein kinase 2

(2022) Wenpeng Cao et al.   Bioengineered

Bisdemethoxycurcumin suppresses human brain glioblastoma multiforme GBM 8401 cell migration and invasion via affecting NF‐κB and MMP ‐2 and MMP ‐9 signaling pathway in vitro

(2022) Chiung‐Ju Chen et al.   ENVIRONMENTAL TOXICOLOGY

Advancements in Activating Transcription Factor 5 Function in Regulating Cell Stress and Survival

(2022) Pameila Paerhati et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clinical Significance and Molecular Annotation of Cellular Morphometric Subtypes in Lower Grade Gliomas discovered by Machine Learning

(2022) Xiao-Ping Liu et al.   NEURO-ONCOLOGY

The dual role of boron in vitro neurotoxication of glioblastoma cells via SEMA3F / NRP2 and ferroptosis signaling pathways

(2022) Fatih Kar et al.   ENVIRONMENTAL TOXICOLOGY

Long non-coding RNA NEAT1 mediated RPRD1B stability facilitates fatty acid metabolism and lymph node metastasis via c-Jun/c-Fos/SREBP1 axis in gastric cancer

(2022) Yongxu Jia et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Prognostic role of c‐Jun activation domain‐binding protein‐1 in cancer: A systematic review and meta‐analysis

(2021) Deyao Shi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Demethoxycurcumin Suppresses Proliferation, Migration, and Invasion of Human Brain Glioblastoma Multiforme GBM 8401 Cells via PI3K/Akt Pathway

(2021) RUEI-YU SU et al.   ANTICANCER RESEARCH

MicroRNA‑218 inhibits the malignant phenotypes of glioma by modulating the TNC/AKT/AP‑1/TGFβ1 feedback signaling loop

(2021) Siwen Dang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Therapeutic Effect of IL-4 Receptor-Targeting Pro-Apoptotic Peptide (AP1-ELP-KLAK) in Glioblastoma Tumor Model

(2021) Vijaya Sarangthem et al.   International Journal of Nanomedicine

Signaling of MK2 sustains robust AP1 activity for triple negative breast cancer tumorigenesis through direct phosphorylation of JAB1

(2021) Haoming Chen et al.   npj Breast Cancer

Sodium Butyrate Enhances Curcuminoids Permeability through the Blood-Brain Barrier, Restores Wnt/β-Catenin Pathway Antagonists Gene Expression and Reduces the Viability of Glioblastoma Cells

(2021) Aleksandra Majchrzak-Celińska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Impact of the APE1 Redox Function Inhibitor E3330 in Non-Small Cell Lung Cancer Cells Exposed to Cisplatin: Increased Cytotoxicity and Impairment of Cell Migration and Invasion

(2020) Rita Manguinhas et al.   Antioxidants

Ferroptosis, a new form of cell death: opportunities and challenges in cancer

(2019) Yanhua Mou et al.   Journal of Hematology & Oncology

Natural products targeting the PI3K-Akt-mTOR signaling pathway in cancer: A novel therapeutic strategy

(2019) Devesh Tewari et al.   SEMINARS IN CANCER BIOLOGY

Liposomal TriCurin, A Synergistic Combination of Curcumin, Epicatechin Gallate and Resveratrol, Repolarizes Tumor-Associated Microglia/Macrophages, and Eliminates Glioblastoma (GBM) and GBM Stem Cells

(2018) Sumit Mukherjee et al.   MOLECULES

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Terpinen-4-ol inhibits colorectal cancer growth via reactive oxygen species

(2017) Ken Nakayama et al.   Oncology Letters

Selective activator protein-1 inhibitor T-5224 prevents lymph node metastasis in an oral cancer model

(2016) Daisuke Kamide et al.   CANCER SCIENCE

Curcumin, an active component of turmeric (Curcuma longa), and its effects on health

(2015) Betül Kocaadam et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

(2015) Francesca Zanconato et al.   NATURE CELL BIOLOGY

β-elemene enhances both radiosensitivity and chemosensitivity of glioblastoma cells through the inhibition of the ATM signaling pathway

(2015) SIWEI LIU et al.   ONCOLOGY REPORTS