Treatment with semaglutide, a GLP-1 receptor agonist, improves extracellular matrix remodeling in the pancreatic islet of diet-induced obese mice

MicroRNA-29 Ameliorates Fibro-Inflammation and Insulin Resistance in HIF1α-Deficient Obese Adipose Tissue by Inhibiting Endotrophin Generation

(2022) Woobeen Jo et al.   DIABETES

Determinants and dynamics of pancreatic islet architecture

(2022) Melissa T. Adams et al.   Islets

A human pancreatic ECM hydrogel optimized for 3-D modeling of the islet microenvironment

(2022) Daniel M. Tremmel et al.   Scientific Reports

The Mechanism for Adipose Endotrophin Production

(2022) Yun Sok Lee   DIABETES

The obesity and nonalcoholic fatty liver disease mouse model revisited: Liver oxidative stress, hepatocyte apoptosis, and proliferation

(2022) Pedro H. Reis-Barbosa et al.   ACTA HISTOCHEMICA

Management of hyperglycaemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

(2022) Melanie J. Davies et al.   DIABETOLOGIA

Cell surface glycosaminoglycans exacerbate plasma membrane perturbation induced by the islet amyloid polypeptide

(2021) Noé Quittot et al.   FASEB JOURNAL

A Structure-Based Discovery Platform for BACE2 and the Development of Selective BACE Inhibitors

(2021) Yu-Chen Yen et al.   ACS Chemical Neuroscience

Nutritional Research and Fetal Programming: Parental Nutrition Influences the Structure and Function of the Organs

(2021) Marcia Barbosa Aguila et al.   INTERNATIONAL JOURNAL OF MORPHOLOGY

Collagen VI as a driver and disease biomarker in human fibrosis

(2021) Lynn Williams et al.   FEBS Journal

Obese mice weight loss role on nonalcoholic fatty liver disease and endoplasmic reticulum stress treated by a GLP-1 receptor agonist

(2021) Rayane Miranda Pontes-da-Silva et al.   INTERNATIONAL JOURNAL OF OBESITY

Pancreatic islet cells disarray, apoptosis, and proliferation in obese mice. The role of Semaglutide treatment

(2021) Thatiany de Souza Marinho et al.   BIOCHIMIE

Mice as an Animal Model for the Study of Adipose Tissue and Obesity

(2021) Carlos Alberto Mandarim-de-Lacerda et al.   INTERNATIONAL JOURNAL OF MORPHOLOGY

A systematic approach to quantitative Western blot analysis

(2020) Lakshmi Pillai-Kastoori et al.   ANALYTICAL BIOCHEMISTRY

Liraglutide promotes the angiogenic ability of human umbilical vein endothelial cells through the JAK2/STAT3 signaling pathway

(2020) Yanbo Di et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

(2020) Nathalie Percie du Sert et al.   EXPERIMENTAL PHYSIOLOGY

Cell Energy Metabolism and Hyaluronan Synthesis

(2020) Ilaria Caon et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Glucagon like peptide-1 receptor agonists as neuroprotective agents for ischemic stroke: a systematic scoping review

(2020) Mark P Maskery et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Collagen and endothelial cell co-culture improves β-cell functionality and rescues pancreatic ECM

(2020) Aline Zbinden et al.   TISSUE ENGINEERING PART A

GLP-1 receptor agonists in the treatment of type 2 diabetes – state-of-the-art

(2020) Michael A. Nauck et al.   Molecular Metabolism

The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases

(2020) Griselda A Cabral-Pacheco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Heparanase and the hallmarks of cancer

(2020) Krishnath M. Jayatilleke et al.   Journal of Translational Medicine

Type VI collagen and its cleavage product, endotrophin, cooperatively regulate the adipogenic and lipolytic capacity of adipocytes

(2020) Jiyoung Oh et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

IAPP in type II diabetes: Basic research on structure, molecular interactions, and disease mechanisms suggests potential intervention strategies

(2018) Shreyasi Asthana et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The toxic nature of murine amylin and the immune responsivity of pancreatic islet to conformational antibody in mice

(2018) Luiza C. S. Erthal et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Loss of intra-islet heparan sulfate is a highly sensitive marker of type 1 diabetes progression in humans

(2018) Charmaine J. Simeonovic et al.   PLoS One

Rebuilding a better home for transplanted islets

(2018) Daniel M. Tremmel et al.   Organogenesis

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Glucose dysregulation and response to common anti-diabetic agents in the FATZO/Pco mouse

(2017) Richard G. Peterson et al.   PLoS One

Composition and organization of the pancreatic extracellular matrix by combined methods of immunohistochemistry, proteomics and scanning electron microscopy

(2017) S. Vigier et al.   Current Research in Translational Medicine

Discovery of ethyl urea derivatives as inhibitors of islet amyloid polypeptide fibrillization and cytotoxicity

(2016) Jessica S. Fortin et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Wildlife sequences of islet amyloid polypeptide (IAPP) identify critical species variants for fibrillization

(2015) Jessica S. Fortin et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis

(2015) Marie E. Oskarsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronan

(2015) Rebecca L. Hull et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Divergent effect of glycosaminoglycans on the in vitro aggregation of serum amyloid A

(2014) J. Javier Aguilera et al.   BIOCHIMIE

Extracellular Matrix Components in the Pathogenesis of Type 1 Diabetes

(2014) Marika Bogdani et al.   Current Diabetes Reports

Hyaluronan: A simple polysaccharide with diverse biological functions

(2013) Kevin T. Dicker et al.   Acta Biomaterialia

A New Method for Quantitative Real-Time Polymerase Chain Reaction Data Analysis

(2013) Xiayu Rao et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Syndecan-4 is associated with beta-cells in the pancreas and the MIN6 beta-cell line

(2012) Jennifer Y. C. Cheng et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Hyaluronan and Hyaluronan Binding Proteins Are Normal Components of Mouse Pancreatic Islets and Are Differentially Expressed by Islet Endocrine Cell Types

(2012) Rebecca L. Hull et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Heparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetes

(2011) Andrew F. Ziolkowski et al.   JOURNAL OF CLINICAL INVESTIGATION

A Mouse Model of Metabolic Syndrome: Insulin Resistance, Fatty Liver and Non-Alcoholic Fatty Pancreas Disease (NAFPD) in C57BL/6 Mice Fed a High Fat Diet

(2010) Julio C. Fraulob et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Extracellular Matrix in Pancreatic Islets: Relevance to Scaffold Design and Transplantation

(2009) John C. Stendahl et al.   CELL TRANSPLANTATION

A protocol for islet isolation from mouse pancreas

(2009) Dong-Sheng Li et al.   Nature Protocols