Genetically Encoded DNA Origami for Gene Therapy In Vivo

Active Nuclear Import of Mammalian Cell-Expressible DNA Origami

(2023) Anna Liedl et al.   Journal of the American Chemical Society

Gene-encoding DNA origami for mammalian cell expression

(2023) Jessica A. Kretzmann et al.   Nature Communications

Transfected plasmid DNA is incorporated into the nucleus via nuclear envelope reformation at telophase

(2022) Tokuko Haraguchi et al.   Communications Biology

Frame-Guided Assembly of Amphiphiles

(2022) Yuanchen Dong et al.   ACCOUNTS OF CHEMICAL RESEARCH

DNA Soccer-Ball Framework Templated Liposome Formation with Precisely Regulated Nucleation Seeds

(2022) Yunyun Xu et al.   ACS Nano

Ordered and deterministic cancer genome evolution after p53 loss

(2022) Timour Baslan et al.   NATURE

Drugging p53 in cancer: one protein, many targets

(2022) Ori Hassin et al.   NATURE REVIEWS DRUG DISCOVERY

An Infectious Virus‐like Particle Built on a Programmable Icosahedral DNA Framework**

(2022) Yunyun Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA Functional Materials Assembled from Branched DNA: Design, Synthesis, and Applications

(2020) Yuhang Dong et al.   CHEMICAL REVIEWS

Role of nanoscale antigen organization on B-cell activation probed using DNA origami

(2020) Rémi Veneziano et al.   Nature Nanotechnology

A DNA nanodevice-based vaccine for cancer immunotherapy

(2020) Shaoli Liu et al.   NATURE MATERIALS

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

(2019) Paul S. Kwon et al.   Nature Chemistry

The approved gene therapy drugs worldwide: from 1998 to 2019

(2019) Cui-Cui Ma et al.   BIOTECHNOLOGY ADVANCES

Paranemic Crossover DNA: There and Back Again

(2018) Xing Wang et al.   CHEMICAL REVIEWS

DNA Nanotechnology-Enabled Drug Delivery Systems

(2018) Qinqin Hu et al.   CHEMICAL REVIEWS

A DNA-Based Nanocarrier for Efficient Gene Delivery and Combined Cancer Therapy

(2018) Jianbing Liu et al.   NANO LETTERS

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

Complex silica composite nanomaterials templated with DNA origami

(2018) Xiaoguo Liu et al.   NATURE

Solving mazes with single-molecule DNA navigators

(2018) Jie Chao et al.   NATURE MATERIALS

DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury

(2018) Dawei Jiang et al.   Nature Biomedical Engineering

Single-stranded DNA and RNA origami

(2017) Dongran Han et al.   SCIENCE

DNA nanotechnology

(2017) Nadrian C. Seeman et al.   Nature Reviews Materials

Precisely Controlled 2D Free-Floating Nanosheets of Amphiphilic Molecules through Frame-Guided Assembly

(2016) Chao Zhou et al.   ADVANCED MATERIALS

Directional Regulation of Enzyme Pathways through the Control of Substrate Channeling on a DNA Origami Scaffold

(2016) Guoliang Ke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cuboid Vesicles Formed by Frame-Guided Assembly on DNA Origami Scaffolds

(2016) Yuanchen Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Optimized DNA “Nanosuitcases” for Encapsulation and Conditional Release of siRNA

(2016) Katherine E. Bujold et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transfer of molecular recognition information from DNA nanostructures to gold nanoparticles

(2016) Thomas G. W. Edwardson et al.   Nature Chemistry

Self-assembly of size-controlled liposomes on DNA nanotemplates

(2016) Yang Yang et al.   Nature Chemistry

Molecular force spectroscopy with a DNA origami–based nanoscopic force clamp

(2016) Philipp C. Nickels et al.   SCIENCE

Self-assembly of DNA Nanohydrogels with Controllable Size and Stimuli-Responsive Property for Targeted Gene Regulation Therapy

(2015) Juan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gene therapy returns to centre stage

(2015) Luigi Naldini   NATURE

A pH-independent DNA nanodevice for quantifying chloride transport in organelles of living cells

(2015) Sonali Saha et al.   Nature Nanotechnology

Dynamic DNA devices and assemblies formed by shape-complementary, non-base pairing 3D components

(2015) T. Gerling et al.   SCIENCE

Programmable materials and the nature of the DNA bond

(2015) M. R. Jones et al.   SCIENCE

Single-Molecule Imaging of Dynamic Motions of Biomolecules in DNA Origami Nanostructures Using High-Speed Atomic Force Microscopy

(2014) Masayuki Endo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Functional DNA-Containing Nanomaterials: Cellular Applications in Biosensing, Imaging, and Targeted Therapy

(2014) Hao Liang et al.   ACCOUNTS OF CHEMICAL RESEARCH

DNA Origami Structures Directly Assembled from Intact Bacteriophages

(2014) Philipp C. Nickels et al.   Small

Functional DNA Nanostructures for Theranostic Applications

(2013) Hao Pei et al.   ACCOUNTS OF CHEMICAL RESEARCH

Structural basis for molecular recognition of folic acid by folate receptors

(2013) Chen Chen et al.   NATURE

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

DNA Origami with Double-Stranded DNA As a Unified Scaffold

(2012) Yang Yang et al.   ACS Nano

Self-assembled RNA interference microsponges for efficient siRNA delivery

(2012) Jong Bum Lee et al.   NATURE MATERIALS

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Three-Dimensional Structures Self-Assembled from DNA Bricks

(2012) Y. Ke et al.   SCIENCE

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Cellular Immunostimulation by CpG-Sequence-Coated DNA Origami Structures

(2011) Verena J. Schüller et al.   ACS Nano

DNA Origami with Complex Curvatures in Three-Dimensional Space

(2011) D. Han et al.   SCIENCE

Folding DNA Origami from a Double-Stranded Source of Scaffold

(2009) Björn Högberg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polymerase Chain Reaction Based Scaffold Preparation for the Production of Thin, Branched DNA Origami Nanostructures of Arbitrary Sizes

(2009) Elisabeth Pound et al.   NANO LETTERS

Self-assembly of DNA into nanoscale three-dimensional shapes

(2009) Shawn M. Douglas et al.   NATURE

Self-assembly of a nanoscale DNA box with a controllable lid

(2009) Ebbe S. Andersen et al.   NATURE

Folding DNA into Twisted and Curved Nanoscale Shapes

(2009) H. Dietz et al.   SCIENCE

Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra

(2008) Yu He et al.   NATURE