Article
Nutrition & Dietetics
Rosalyn J. Singleton, Gretchen M. Day, Timothy K. Thomas, Joseph A. Klejka, Christine A. Desnoyers, Melanie N. P. McIntyre, David M. Compton, Kenneth E. Thummel, Robert J. Schroth, Leanne M. Ward, Dane C. Lenaker, Rachel K. Lescher, Joseph B. McLaughlin
Summary: The study found that prenatal vitamin D supplementation in high-risk populations can improve childhood outcomes regarding rickets and dental caries.
Article
Public, Environmental & Occupational Health
Eynav E. Accortt, Chander Arora, James Mirocha, Susan Jackman, Richard Liang, S. Ananth Karumanchi, Anders H. Berg, Calvin J. Hobel
Summary: The study found that lower Vitamin D Metabolite Ratio (VMR) and Hispanic/Latina identification during pregnancy are significantly associated with higher risk of postpartum depression (PPD). This suggests that routine prenatal screening for vitamin D metabolites, especially in Hispanic/Latina women, may help identify individuals at risk for PPD.
JOURNAL OF WOMENS HEALTH
(2021)
Article
Multidisciplinary Sciences
Hui Xu, Qian Wang, Ting Li, Yuanyuan Wang, Ruiyao Cao, Xingwang Peng, Rongying Yao, Hui Han, Rui Zhou, Lianguo Fu
Summary: This study examines the association between prenatal androgens and cord blood androgens concentrations. The concentrations of T, FT, DHT, DHEA, and SHBG were measured in prenatal venous blood and cord blood of 342 pregnant women and their neonates. The results revealed gender differences in cord blood androgen concentrations, as well as differences between prenatal and cord blood androgens levels.
SCIENTIFIC REPORTS
(2023)
Article
Genetics & Heredity
Paul Madley-Dowd, Christina Dardani, Robyn E. Wootton, Kyle Dack, Tom Palmer, Rupert Thurston, Alexandra Havdahl, Jean Golding, Deborah Lawlor, Dheeraj Rai
Summary: This study found no strong evidence of a causal link between maternal vitamin D levels during pregnancy and the diagnosis or traits of autism.
Review
Nutrition & Dietetics
Gianina Tapalaga, Bogdan Andrei Bumbu, Sandhya Rani Reddy, Sai Diksha Vutukuru, Akhila Nalla, Felix Bratosin, Roxana Manuela Fericean, Catalin Dumitru, Doru Ciprian Crisan, Nicoleta Nicolae, Magda Mihaela Luca
Summary: Prenatal Vitamin D levels may have an impact on dental health outcomes in children. The association between Vitamin D levels and enamel defects and tooth erosion varied across different studies. Vitamin D insufficiency was identified as a significant risk factor for enamel defects, while high prenatal Vitamin D levels indicated a protective effect against Hypomineralized Second Primary Molars and Molar Incisor Hypomineralization. However, there were variations in the assessment and prevalence of Vitamin D deficiency or insufficiency, and more research is needed to determine the optimal Vitamin D intake during pregnancy.
Article
Nutrition & Dietetics
Julia Sanguesa, Sandra Marquez, Mariona Bustamante, Jordi Sunyer, Carmen Iniguez, Jesus Vioque, Loreto Santa-Marina Rodriguez, Alba Jimeno-Romero, Matias Torrent, Maribel Casas, Martine Vrijheid
Summary: This study examines the association between prenatal vitamin D levels and growth and adiposity in late childhood. The results suggest a sex-specific programming effect of early pregnancy vitamin D levels on offspring body composition, which is observed in boys but not in girls.
Article
Immunology
Tracy A. Becerra-Culqui, Darios Getahun, Vicki Chiu, Lina S. Sy, Hung Fu Tseng
Summary: This study investigated the association between prenatal influenza vaccination or infection and autism spectrum disorder (ASD) in offspring. The findings showed no association between prenatal influenza vaccination or infection and ASD risk in children.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Nutrition & Dietetics
Iskander LC. Shadid, Nicklas Brustad, Mengdi Lu, Bo L. Chawes, Hans Bisgaard, Robert S. Zeiger, George T. O'Connor, Leonard B. Bacharier, Henk-Jan Guchelaar, Augusto A. Litonjua, Scott T. Weiss, Hooman Mirzakhani
Summary: Prenatal vitamin D deficiency is associated with offspring asthma or recurrent wheezing. However, evidence on the efficacy of vitamin D supplementation is inconclusive. This study aimed to examine the efficacy of prenatal vitamin D supplementation based on maternal baseline vitamin D status and timing of supplementation, and found that supplementation was beneficial regardless of baseline vitamin D levels, with the greatest reduction in asthma or wheezing observed in severely vitamin D-deficient women.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Allergy
Mengdi Lu, Augusto A. Litonjua, George T. O'Connor, Robert S. Zeiger, Leonard Bacharier, Michael Schatz, Vincent J. Carey, Scott T. Weiss, Hooman Mirzakhani
Summary: Childhood asthma development is affected by a complex interplay of maternal asthma and prenatal vitamin D status. This study suggests that adequate vitamin D intake throughout pregnancy can help reduce the risk of childhood asthma exacerbated by maternal asthma.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2021)
Review
Nutrition & Dietetics
Jose Luis Mansur, Beatriz Oliveri, Evangelina Giacoia, David Fusaro, Pablo Rene Costanzo
Summary: Vitamin D deficiency in pregnancy and infants may lead to health issues such as rickets, preeclampsia, and fetal growth restriction; supplementation with Vitamin D can reduce the risk of complications for pregnant women, fetuses, and newborns.
Article
Nutrition & Dietetics
Jinhua Wu, Bule Shao, Xing Xin, Wenliang Luo, Minjia Mo, Wen Jiang, Shuting Si, Shuojia Wang, Yu Shen, Yunxian Yu
Summary: This study explored the associations of vitamin D metabolic pathway gene polymorphisms with gestational 25(OH)D levels in pregnant women, and found that the associations varied by season and VD supplements. Additionally, the Gc isoform had a significant impact on gestational 25(OH)D levels.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Benjamin Levy, Karen M. O'Callaghan, Huma Qamar, Abdullah Al Mahmud, Alison D. Gernand, M. Munirul Islam, Daniel E. Roth
Summary: Variability in maternal and infant 25(OH)D levels following vitamin D supplementation is largely determined by supplemental vitamin D intake and initial 25(OH)D levels. Other characteristics contribute minimally to the variance. Maternal delivery 25(OH)D and prenatal vitamin D intake are the major determinants of neonatal 25(OH)D levels. The variance in later infancy 25(OH)D can only be partly explained by various biological, sociodemographic, and laboratory-related characteristics.
JOURNAL OF NUTRITION
(2021)
Review
Endocrinology & Metabolism
Jelena Dukic, Ulrike Ehlert
Summary: This study aimed to establish an overview of sex steroid secretion patterns during the peripartum and understand their contribution to maternal and fetal pathologies. The findings revealed a progressive increase in sex steroids levels during pregnancy, but with wide variations in measurement results. The current knowledge on the association between sex steroids and pathologies is mainly based on correlational studies, and causality remains unclear.
Article
Environmental Sciences
Zorimar Rivera-Nunez, Carolyn W. Kinkade, Leena Khoury, Jessica Brunner, Hannah Murphy, Christina Wang, Kurunthachalam Kannan, Richard K. Miller, Thomas G. O'Connor, Emily S. Barrett
Summary: The study found that maternal serum levels of poly- and perfluoroalkyl substances (PFAS) are associated with sex steroid hormone levels during pregnancy. Specifically, PFHxS is associated with increased testosterone levels in male fetuses, while PFNA and PFDA are associated with increased free testosterone levels in male fetuses. For female fetuses, PFHxS is associated with increased levels of estradiol and estriol. No associations were found for PFOS and PFOA.
ENVIRONMENTAL RESEARCH
(2023)
Article
Nutrition & Dietetics
Lisa Daneels, Dries S. Martens, Soumia Arredouani, Jaak Billen, Gudrun Koppen, Roland Devlieger, Tim S. Nawrot, Manosij Ghosh, Lode Godderis, Sara Pauwels
Summary: The study found a positive association between maternal vitamin D intake (diet + supplements) and newborn TL, particularly during the first trimester. However, there was no significant association between mean maternal serum 25-OHD concentrations during pregnancy and newborn TL.