Article
Plant Sciences
Sabine Scandola, Devang Mehta, Brigo Castillo, Nicholas Boyce, R. Glen Uhrig
Summary: In this study, we analyzed the morphology, proteomics, and metabolomics of nine kale cultivars to reveal the diel proteome and metabolome signatures and related biological activities. The findings have important theoretical and practical implications for improving the cultivation and vertical farming applications of kale.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Environmental Sciences
Chinnaperumal Kamaraj, Pachiyappan Rajiv Gandhi, Rajappan Chandra Satish Kumar, Govindasamy Balasubramani, Guilherme Malafaia
Summary: The ability of plant extracts to collect metals and reduce metal ions makes them a superior candidate for the biosynthesis of nanoparticles. This study examined the antiparasitic activity of biosynthesized copper oxide nanoparticles against cow tick larvae and other parasitic insects. The results demonstrated that biosynthesized CuO NPs showed maximum efficacy against the tested parasites, indicating the potential for developing better and safer antiparasitic control techniques.
ENVIRONMENTAL RESEARCH
(2022)
Article
Chemistry, Medicinal
Kamaraj Murugesan, Kidist Mulugeta, Eyosias Hailu, Worku Tamene, Sangilimuthu Alagar Yadav
Summary: The study focused on investigating the phytochemical and antimicrobial activity of Ethiopian Kale leaves infusions, as well as analyzing the antioxidant activity and major phytochemicals in the better solvent system. The findings indicated that the ethanol extract of Ethiopian Kale leaves is a rich source of phytochemicals and has potential for various functional applications.
CHINESE HERBAL MEDICINES
(2021)
Article
Biochemistry & Molecular Biology
Areej Al-Qahtani, Jamaan Ajarem, Mohammad K. Okla, Samina Rubnawaz, Saud A. Alamri, Wahidah H. Al-Qahtani, Ahmad R. Al-Himaidi, Hamada Abd Elgawad, Nosheen Akhtar, Saleh N. Maodaa, Mostafa A. Abdel-Maksoud
Summary: The study demonstrates that green tea supplementation can protect against lead-induced toxicity in mice by ameliorating body weight, blood glucose, blood picture, and behavioral alterations.
Article
Food Science & Technology
Tabeen Khursheed, Tabasum Fatima, Tahiya Qadri, Asima Rafiq, Ajaz Malik, Bazila Naseer, Syed Zameer Hussain
Summary: A comprehensive study was conducted to compare the physiochemical, nutritional, and bioactive profiles of chia and basil seeds. Basil seeds were found to have higher content of dietary fiber, fat, vitamin A and E, while chia seeds were richer in protein, iron, magnesium, and phosphorus. Chia seeds also contained a more diverse range of amino acids and higher levels of alpha-linoleic acid. Basil seeds had higher amounts of total phenolic and flavonoid content, contributing to their higher antioxidant activity.
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
(2023)
Article
Environmental Sciences
Ting Chen, Xuan Zheng, Xiao He, Yan You, Guanghan Huang, Yihuan Cao, Liqiang He, Ye Wu
Summary: A new method was developed to comprehensively characterize the emissions of polycyclic aromatic hydrocarbons (PAHs) from diesel vehicles. The study found that the total PAH emissions from diesel vehicles are highly toxic and aftertreatment technologies can significantly reduce PAH emissions.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Analytical
Chao Han, Chaoqun Huang, Qinting Jiang, Li Chen, Yi Li, Chengjie Lou, Hailing Lu, Yan Shen
Summary: A novel and accurate method for the determination of folpet and phthalimide residues in tea has been developed, using solid-phase extraction combined with gas chromatography-tandem mass spectrometry. The method proposes converting all folpet to phthalimide prior to sample extraction and purification, and utilizes an isotopic internal standard for quantification. The study confirms the accurate determination of phthalimide content and its conversion to folpet content.
MICROCHEMICAL JOURNAL
(2022)
Article
Environmental Sciences
Asha Lata Singh, Sneha Chaudhary, Sunil Kumar, Aniruddha Kumar, Achuit Singh, Akhilesh Yadav
Summary: This study successfully degraded and decolorized RY-145 dye using a mixed bacterial consortium of E. asburiae and E. cloacae. The optimal conditions for maximum degradation and decolorization were determined. Biochemical analysis identified several compound metabolites with industrial applications. Toxicity tests and genotoxicity studies demonstrated the reduced toxicity of the treated dye.
Article
Chemistry, Applied
Bing Lyu, Xiaoyan Zhang, Jingguang Li, Lei Zhang, Yuxin Zhong, Yongning Wu
Summary: The present study evaluated two GC-MS/MS instruments with different ion sources for detecting trace levels of PCDD/Fs in various foods. The GC-MS/MS methods showed good sensitivity, repeatability, and reproducibility, and the results were comparable to those obtained with GC-HRMS.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Nutrition & Dietetics
Denis Baranenko, Mohamed Said Boulkrane, Irina Borisova, Bazhena Astafyeva, Weihong Lu, A. M. Abd El-Aty
Summary: There is increasing concern about the potential health risks of exposure to phthalates. This study investigated the presence of phthalates in packaged beef samples and their translocation from different types of food packaging. The results showed that di-n-butyl phthalate (DnBP) had the highest levels in beef, while diisooctyl phthalate (DiOP) had the lowest levels. The contact area and fat content on minced meat resulted in higher phthalate translocation compared to beef slices. However, the examined food packages did not meet the legal requirements, as DnBP migrated to the meat. Further research is needed to determine the migration pathways and sources of phthalates in the food chain.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Applied
Xuejie Li, Xiangquan Zeng, Huanlu Song, Yu Xi, Yan Li, Bowen Hui, He Li, Jian Li
Summary: GC x GC-O-TOF-MS and GC-IMS have been increasingly used in complex food flavor analysis, but few studies have applied these techniques to identify the aroma components of tomato pastes. This study comprehensively characterized the aroma profiles of cold and hot break tomato pastes using SAFE-GC-O-MS, SAFE-GC x GC-O-TOF-MS, and HS-GC-IMS for the first time. A total of 274 volatile compounds were identified, which is far more than previously reported.
Article
Chemistry, Applied
Mu Zhao, Ting Li, Fan Yang, Xinyue Cui, Tingting Zou, Huanlu Song, Ye Liu
Summary: This study characterized the composition of volatile aroma compounds and key aroma-active compounds in dried Hanyuan Zanthoxylum bungeanum. The results identified several key aroma-active compounds such as myrcene and limonene.
Article
Chemistry, Applied
Lara Davani, Elisa Tassinari, Stefano Chiaberge, Andrea Siviero, Luca Serbolisca, Vincenzo Tumiatti, Cristina Terenzi, Angela De Simone, Vincenza Andrisano, Serena Montanari
Summary: In this study, a fast ultrasound solid-liquid extraction method was optimized to determine the content of Bisphenol A (BPA) in commercial microalgal powders. The method was validated by GC-MS analysis and proved to be fast, with high recovery and suitable to selectively and sensitively determine the content of BPA, allowing to control the safety profile of microalgae.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Applied
Yanqin Yang, Jialing Xie, Qiwei Wang, Yuliang Deng, Li Zhu, Jiayi Zhu, Haibo Yuan, Yongwen Jiang
Summary: This study comprehensively characterized the volatile and non-volatile compounds during black tea processing using volatolomics and UHPLC-Q-Exactive/MS analysis. The results showed that these metabolites changed continuously throughout the processing process, with significant changes during the withering stage. A total of 178 volatile metabolites and 103 non-volatile metabolites were identified, and 11 volatile components were identified as key aroma active components responsible for sweet aroma in finished black tea.
Article
Toxicology
Ana Margarida Araujo, Marcia Carvalho, Vera Marisa Costa, Jose Alberto Duarte, Ricardo Jorge Dinis-Oliveira, Maria de Lourdes Bastos, Paula Guedes de Pinho, Felix Carvalho
Summary: The study revealed metabolic changes induced by MDPV in mice using metabolomics analysis, with kidneys and liver showing the greatest metabolic alterations. Metabolites related to energetic metabolism, antioxidant defenses, and inflammatory response were significantly changed in the liver. Urine metabolites suggested that glutathione-dependent antioxidant pathways may be involved in counteracting oxidative stress induced by MDPV.
ARCHIVES OF TOXICOLOGY
(2021)
Article
Microbiology
Jared N. Balaich, Derrick K. Mathias, Baldwyn Torto, Bryan T. Jackson, Dingyin Tao, Babak Ebrahimi, Brian B. Tarimo, Xavier Cheseto, Woodbridge A. Foster, Rhoel R. Dinglasan
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2016)
Article
Agriculture, Multidisciplinary
Xavier Cheseto, Donald L. Kachigamba, Sunday Ekesi, Mary Ndung'u, Peter E. A. Teal, John J. Beck, Baldwyn Torto
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2017)
Article
Parasitology
Valentine C. Mbatchou, David P. Tchouassi, Rita A. Dickson, Kofi Annan, Abraham Y. Mensah, Isaac K. Amponsah, Julia W. Jacob, Xavier Cheseto, Solomon Habtemariam, Baldwyn Torto
PARASITES & VECTORS
(2017)
Article
Agriculture, Multidisciplinary
Xavier Cheseto, Donald L. Kachigamba, Mwanasiti Benderap, Sunday Ekesi, Mary Ndung'u, John J. Beck, Baldwyn Torto
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2018)
Article
Multidisciplinary Sciences
Vincent O. Nyasembe, Xavier Cheseto, Fatma Kaplan, Woodbridge A. Foster, Peter E. A. Teal, James H. Tumlinson, Christian Borgemeister, Baldwyn Torto
Article
Multidisciplinary Sciences
Robert Musundire, Isaac M. Osuga, Xavier Cheseto, Janet Irungu, Baldwyn Torto
Article
Parasitology
Steven Dyer, Ryan Weir, Deborah Cox, Xavier Cheseto, Baldwyn Torto, Johnathan J. Dalzell
INTERNATIONAL JOURNAL FOR PARASITOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Bethelihem Mekonnen, Xavier Cheseto, Christian Pirk, Abdullahi Yusuf, Sunday Ekesi, Emilie Deletre, Baldwyn Torto
Summary: The African weaver ant, used as a biological control agent for pest management, has various exocrine glands in the abdomen with unique chemical compositions, potentially influencing the physiological and behavioral functions of the ant species.
Article
Infectious Diseases
Iman B. Hassaballa, Catherine L. Sole, Xavier Cheseto, Baldwyn Torto, David P. Tchouassi
Summary: The study reveals plant feeding associations in field-collected sand flies from a dry ecology endemic for leishmaniasis in Kenya, showing similar rates of plant feeding among sand fly sexes sampled from indoor and outdoor environments, mainly foraging on Acacia plants in the family Fabaceae. The results suggest that discriminating volatile organic compounds from selected Fabaceae plants could be used in sand fly control strategies.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Article
Multidisciplinary Sciences
Justice Kwaku Addo, Ernest Owusu-Ansah, Nicholas T. K. D. Dayie, Xavier Cheseto, Baldwyn Torto
Summary: This study synthesized ten 1,2,3-triazole-thymol derivatives and demonstrated significant but variable antibacterial activity against seven medically important bacterial strains, indicating the potential of natural products like thymol as leads for drug development.
Article
Agronomy
Xavier Cheseto, Hillary Kirwa, Samira Abuelgasim Mohamed, Sunday Ekesi, John J. Beck, Baldwyn Torto
Summary: The study found that glutathione (GSH) and glutamic acid (GA) can effectively reduce the offspring population of African fruit flies (Ceratitis cosyra and Ceratitis rosa) in Kenyan mango orchards, but have little impact on Bactrocera dorsalis. This research provides a potential method for managing African fruit fly species using host marking pheromones (HMPs).
PEST MANAGEMENT SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Xavier Cheseto, Caitlin C. Rering, Geoffrey T. Broadhead, Baldwyn Torto, John J. Beck
Summary: The infestation of agricultural commodities by insect pests, such as the highly invasive Oriental fruit fly (Bactrocera dorsalis), poses economic, import and export, food safety, and invasive insect introduction issues. Detecting infestations early on is crucial for ensuring food safety and controlling the spread of invasive insects. This study investigated the odors of infested mangoes to identify compounds that can be used for rapid and non-destructive detection of infested fruit.
Article
Multidisciplinary Sciences
Marcasy P. Makokha, Patrick S. Muliro, Peninah N. Ngoda, Changeh J. Ghemoh, Sevgan Subramanian, Cheseto Xavier, Brian O. Ochieng, Sunday Ekesi, Chrysantus M. Tanga
Summary: Adding high-valued meat powder to wheat bread can enhance its nutritional value without adverse effects on functional or sensory properties. The inclusion of meat powder increases protein, amino acids, Omega 3 fatty acids, vitamins, and minerals in bread, while improving its color, flavor, and overall acceptability.
Correction
Plant Sciences
Lingmiao Wen, Tinglan Zhang, Fangfang Chen, Lin Hu, Chongyang Dou, Xian Ding, Alvin Altamirano, Guihua Wei, Zhiyong Yan
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Qing Tang, Mengfei Xu, Shunqin Long, Yaya Yu, Changju Ma, Rui Wang, Jing Li, Xi Wang, Fang Fang, Ling Han, Wanyin Wu, Sumei Wang
Summary: This study demonstrates that Fuzheng Kang-Ai (FZKA) decoction can inhibit the cell growth, proliferation, and invasion of lung adenocarcinoma (LUAD) and reverse the acquired resistance of gefitinib. FZKA exerts its effects by regulating the p-ERK1/2-EZH2-Snail/EGFR signaling pathway.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Xiang Zhao, Xianrun Hu, Qi Xie, Shenglan Qi, Zedong Xiang, Xin Sun, Zhejun Xie, Rui Dang, Limei Zhou, Wei Liu, Xuemei Cheng, Changhong Wang
Summary: This study investigated the effects of Fufangmuniziqi formula (FFMN) on Alzheimer's disease (AD) and the role of alkaloids, flavonoids, and saponins in the process. The results showed that FFMN improved cognitive and memory impairment in the AD mouse model. Alkaloids enhanced the cholinergic system, while flavonoids and saponins attenuated neuroinflammation and oxidative stress. These findings suggest that the combination of alkaloid, flavonoid, and saponin fractions derived from FFMN is a promising anti-AD agent.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Bangjian Dong, Ying Peng, Mengyue Wang, Chongsheng Peng, Xiaobo Li
Summary: This study elucidated the tissue distribution and excretion characteristics of the non-polysaccharide components of Sijunzi decoction in rats with spleen deficiency syndrome. It proposed new insights into the rationality of the compatibility of Sijunzi decoction.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Jung-Seop Kim, Man-Gi Kim, Ji Eun Ryu, Ye-Been Lee, Quan Feng Liu, Kwang Ki Kim, Seung-Hun Cho, Sung Joon Shin, Byung-Soo Koo, Hyung-Kyoon Choi
Summary: Co-treatment with WCW and donepezil shows promise in improving cognitive function and serum metabolic profiles in a scopolamine-induced AD model. This combination therapy may reduce tyrosine and methionine levels, enhancing cognitive function by mitigating known risk factors for AD. The study provides a foundation for developing other bioactive compounds in AD treatment.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Kuang-Hsing Chiang, Tain-Junn Cheng, Wei-Chih Kan, Hsien-Yi Wang, Jui-Chen Li, Yan-Ling Cai, Chia-Hui Cheng, Yi-Chien Liu, Chia-Yu Chang, Jiunn-Jye Chuu
Summary: The ethanolic extract of Orthosiphon aristatus (OA) demonstrated an improving effect on memory and could serve as a potential therapeutic target for the treatment of neurodegenerative diseases like Alzheimer's disease (AD).
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Meryem Tourabi, Asmae EL Ghouizi, Ghizlane Nouioura, Khaoula Faiz, Hind Elfatemi, Karima El-yagoubi, Badiaa Lyoussi, Elhoussine Derwich
Summary: Mentha longifolia is a native plant in Morocco, traditionally used to treat various diseases. This study analyzed the phytochemical profile of the aqueous extract of M. longifolia and evaluated its acute and subacute toxicity in mice. The results showed that M. longifolia extract is rich in phenolic compounds and has no observed toxicity up to a certain dosage limit.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Yue Zhang, Liang Li, Tao Chai, Han Xu, Hong-yan Du, Yan Jiang
Summary: Mulberry leaf multi-components (MMC) have hypoglycemic effects and can improve insulin resistance by activating the PI-3K/Akt signaling pathway. These findings highlight the multi-component, multi-target, and combined effects of MMC, and suggest it may be further developed as a hypoglycemic drug.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Correction
Plant Sciences
Shan Luo, Yuanchun Chen, Ruoxi Zhao, Donglai Ma, Yanmeng Zhao, Ying Zhang, Jianming Jiang, Wentao Yu
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Nittaya Chansiw, Pattranuch Chusri, Siwaporn Praman, Thaneeya Hawiset, Wannisa Sukhorum, Sorraya Champakam, Rawiwan Charoensup
Summary: This study evaluates the anti-inflammatory activity of Prabchompoothaweep (PCT) extract in an animal model. The results show that PCT significantly reduces inflammation and pro-inflammatory cytokines in acute and sub-acute inflammation. These findings suggest that PCT could be a new option for the treatment of inflammatory diseases.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Yanting Wang, Guoqiang Liang, Wei Mu, Shu Sun, Xuanyi Chen, Xiaofeng Xu
Summary: Bushen Tianjing Recipe (BTR) is a tonic-kidney formula of Traditional Chinese Medicine (TCM) with good therapeutic effects in clinical settings. The aim of this study was to investigate the effect of BTR on women's reproductive system by incubating miR-23a-induced KGN cells.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Jiayi Zhi, Li Yin, Zhoudong Zhang, Yaozhong Lv, Fan Wu, Yang Yang, Enming Zhang, Huanqiu Li, Ning Lu, Mengze Zhou, Qinghua Hu
Summary: This study verified the pharmacodynamics of JSW in the treatment of AD and explored its potential mechanism using network pharmacology, molecular docking, and experimental validation.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Review
Plant Sciences
Elizabeth Syowai Mutinda, Dong-Juan Zhang, Felix Wambua Muema, Elijah Mbandi Mkala, Emmanuel Nyongesa Waswa, Wyclif Ochieng Odago, Clintone Onyango Ochieng, Moses Kirega Gichua, John Kamau Muchuku, Elizabeth Kamande, Guang-Wan Hu
Summary: This article reviews the traditional uses, pharmacological properties, and phytoconstituents of Balanophora species, revealing that they contain diverse chemical compounds with interesting biological activities. However, research on many species in this genus is still lacking.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Luqi Cai, Yu Chen, Huizhong Xue, Yimeng Yang, Yuqi Wang, Junhe Xu, Chunyan Zhu, Long He, Yonghua Xiao
Summary: Salvia miltiorrhiza Bunge (SM) has been proven to have potential therapeutic effects for diabetic nephropathy (DN) through its multi-component, multi-target, and multi-pathway pharmacological effects.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Chao Wang, Rui-Jia Fu, Ding-Qiao Xu, Qian Zuo, Ji-Ping Liu, Yu-Ping Tang
Summary: This study aimed to explore the hepatoprotective effects of Shicao on CCl4-induced acute liver injury. A rat model of acute liver injury was established and liver function indices were assessed. Untargeted metabolomics was conducted to identify differential metabolites. Network pharmacology was used to construct a network of metabolite-reaction-enzyme-gene constituents, and key components and hub genes were screened. Shicao showed hepatoprotective effects against acute liver injury in rats.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)