Personalised cancer care: promises and challenges of targeted therapy

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

(2014) S. C. Mack et al.   NATURE

The scientific method: pillar and pitfall of cancer research

(2014) Shi-Ming Tu et al.   Cancer Medicine

Cancer: a “stem-cell” disease?

(2013) Shi-Ming Tu   Cancer Cell International

Stem Cell Origin of Testicular Seminoma

(2013) Avik Som et al.   Clinical Genitourinary Cancer

Revisiting DNA damage repair, p53-mediated apoptosis and cisplatin sensitivity in germ cell tumors

(2013) Francesca Cavallo et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Molecular Genetic Evidence Supporting the Origin of Somatic-type Malignancy and Teratoma From the Same Progenitor Cell

(2012) Jennifer B. Kum et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Breast Cancer Stem Cells: We've Got Them Surrounded

(2012) H. Korkaya et al.   CLINICAL CANCER RESEARCH

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Clonal Architecture of Secondary Acute Myeloid Leukemia

(2012) Matthew J. Walter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterizing Mutational Heterogeneity in a Glioblastoma Patient with Double Recurrence

(2012) Gabrielle C. Nickel et al.   PLoS One

Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer

(2012) A. Kreso et al.   SCIENCE

Challenges and opportunities for converting renal cell carcinoma into a chronic disease with targeted therapies

(2011) M E Gore et al.   BRITISH JOURNAL OF CANCER

Hedgehogs, Flies, Wnts and MYCs: The Time Has Come for Many Things in Medulloblastoma

(2011) Michelle Monje et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase III Study of Molecularly Targeted Adjuvant Therapy in Locally Advanced Urothelial Cancer of the Bladder Based on p53 Status

(2011) Walter M. Stadler et al.   JOURNAL OF CLINICAL ONCOLOGY

Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study

(2011) Karen A Gelmon et al.   LANCET ONCOLOGY

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: a study by the Groupe d'Etudes des Lymphomes de l'Adulte

(2010) B. Coiffier et al.   BLOOD

Phase III Study Comparing Gemcitabine Plus Cetuximab Versus Gemcitabine in Patients With Advanced Pancreatic Adenocarcinoma: Southwest Oncology Group–Directed Intergroup Trial S0205

(2010) Philip A. Philip et al.   JOURNAL OF CLINICAL ONCOLOGY

Subtypes of medulloblastoma have distinct developmental origins

(2010) Paul Gibson et al.   NATURE

Inferring tumor progression from genomic heterogeneity

(2009) N. Navin et al.   GENOME RESEARCH

Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial

(2009) Robert Pirker et al.   LANCET

HER2Status and Benefit from Adjuvant Trastuzumab in Breast Cancer

(2008) Soonmyung Paik et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparative lesion sequencing provides insights into tumor evolution

(2008) S. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA