Article
Hematology
Alexandra Schifferli, Gautier Le Gavrian, Nathalie Aladjidi, Guillaume Moulis, Bertrand Godeau, Thomas Kuhne
Summary: Defining immune thrombocytopenia (ITP) in two age groups, children and adults, does not consider the specific clinical features and needs of adolescents and young adults (AYAS). This study reveals that refractory ITP is uncommon in AYAS, but AYAS with refractory ITP display a high disease burden at all time points.
BRITISH JOURNAL OF HAEMATOLOGY
(2023)
Article
Oncology
Mohamed Abdelaal, Pamela J. Mosher, Abha Gupta, Breffni Hannon, Christine Cameron, Malka Berman, Rahim Moineddin, Jonathan Avery, Laura Mitchell, Madeline Li, Camilla Zimmermann, Ahmed Al-Awamer
Summary: Adolescents and young adults with cancer often experience high levels of distress and lack effective palliative care services. Establishing a specialized integrated palliative care and psychiatry clinic has shown promising results in improving symptom scores and end-of-life planning.
Review
Pediatrics
G. Brooks, M. Gazzaneo, M. Bertozzi, G. Riccipetitoni, A. Raffaele
Summary: This review summarizes recent literature on long-term health issues and transitional care in esophageal atresia (EA) patients. It found that the long-term sequelae include gastro-esophageal reflux, dysphagia, esophagitis, Barrett esophagus, anastomotic stricture, and other complications. The study highlights the importance of lifelong follow-up and specialized transitional care for EA patients.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Gastroenterology & Hepatology
James M. Paik, Khaled Kabbara, Katherine E. Eberly, Youssef Younossi, Linda Henry, Zobair M. Younossi
Summary: The study found that the prevalence and mortality rates of chronic liver disease (CLD) have increased among adolescents and young adults aged 15-29, driven primarily by non-alcoholic fatty liver disease (NAFLD). Meanwhile, the proportion of hepatitis B virus (HBV) cases decreased across all age groups, highlighting a shift in the causes of CLD among the younger population.
Article
Oncology
Lauren Ghazal, Maurade Gormley, John D. Merriman, Sheila J. Santacroce
Summary: This study analyzed the concept of financial toxicity in adolescents and young adults diagnosed with cancer. Results identified key antecedents, attributes, and consequences of financial toxicity in this population, highlighting its significance in the context of cancer survivorship.
Article
Pediatrics
Shauna Kingsnorth, Sally Lindsay, Joanne Maxwell, Yani Hamdani, Angela Colantonio, Jingqin Zhu, Mark Theodore Bayley, Colin Macarthur
Summary: The study found that the LIFEspan model improved continuity of care and successful transfer from pediatric to adult services for participants. However, there were no significant changes in healthcare utilization, including physician office visits, emergency department visits, or hospitalizations, for clients enrolled in LIFEspan in the year following discharge compared to the 2 years prior to discharge.
FRONTIERS IN PEDIATRICS
(2021)
Article
Allergy
Ekaterina Khaleva, Rebecca Knibb, Audrey DunnGalvin, Marta Vazquez-Ortiz, Pasquale Comberiati, Cherry Alviani, Teresa Garriga-Baraut, Mary Hazel Gowland, Claudia Gore, Elizabeth Angier, Katharina Blumchen, Bettina Duca, Valerie Hox, Britt Jensen, Charlotte G. Mortz, Helena Pite, Oliver Pfaar, Alexandra F. Santos, Silvia Sanchez-Garcia, Frans Timmermans, Graham Roberts
Summary: This study surveyed patients aged 11-25 with allergies and/or asthma and their parents across Europe, finding that the majority considered the transitional care recommendations important. However, there were conditional approvals for some recommendations.
Article
Hematology
Matthew Greenwood, Toby Trahair, Rosemary Sutton, Michael Osborn, John Kwan, Sally Mapp, Rebecca Howman, Antoinette Anazodo, Brenton Wylie, James D'Rozario, Mark Hertzberg, Ian Irving, David Yeung, Luke Coyle, Amanda Jager, Dan Engeler, Nicola Venn, Chris Frampton, Andrew H. Wei, Kenneth Bradstock, Luciano Dalla-Pozza
Summary: The ALL06 study aimed to evaluate if patients aged 15 to 39 could receive pediatric ALL regimen. The results showed that this therapy was safe and feasible in AYA patients, with similar ability to complete induction/consolidation therapy as children. The study revealed that BMI >30 kg/m(2) and day 79 MRD positivity were associated with poorer disease-free survival and overall survival rates.
Article
Public, Environmental & Occupational Health
Camella J. Rising, Catherine Wilsnack, Patrick Boyd, Alix G. Sleight, Sadie P. Hutson, Payal P. Khincha, Allison Werner-Lin
Summary: This study explored the perspectives, experiences, and challenges of AYAs with LFS in family communication about openness and closedness. AYAs reported navigating openness and closedness in their families based on LFS topic, relationship, disease trajectory, and developmental phase. They described challenges in communication, including broaching difficult topics, balancing information-sharing and emotional protection, and struggling with tensions in interactions.
PATIENT EDUCATION AND COUNSELING
(2022)
Article
Public, Environmental & Occupational Health
Lung-Chih Li, You-Lin Tain, Hsiao-Ching Kuo, Chien-Ning Hsu
Summary: A cohort study in Taiwan found that pediatric and young adult patients on dialysis had a higher risk of cardiovascular disease and mortality compared to adult patients. Non-atherosclerotic cardiovascular disease was more prevalent in younger patients within the first 6 months of dialysis initiation, while atherosclerotic cardiovascular disease risk was higher in adults after 6 months.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Social Work
Christine Cocker, Adi Cooper, Dez Holmes
Summary: This article argues for a transformation in the protection and safeguarding needs of young people during their transition between childhood and adulthood. The workshops revealed challenges in transitional safeguarding practices, with no single local authority having a comprehensive approach.
BRITISH JOURNAL OF SOCIAL WORK
(2022)
Article
Cell Biology
Jun Ah Lee, Jiwon Lim, Hye Young Jin, Meerim Park, Hyeon Jin Park, Jong Woong Park, June Hyuk Kim, Hyun Guy Kang, Young-Joo Won
Summary: The study compared the clinical features and survival rates of osteosarcoma in adolescents and young adults (AYA) with other age groups. It found that AYA had the highest male-to-female ratio, with most tumors located in extremities. The treatment mainly consisted of local treatment and systemic chemotherapy, and the 5-year overall survival rate of AYA was closer to that of children.
Review
Pediatrics
Valentina Biagioli, Giuseppina Spitaletta, Valeria Kania, Rachele Mascolo, Orsola Gawronski, Annachiara Liburdi, Giulia Manzi, Michele Salata, Ercole Vellone, Emanuela Tiozzo, Immacolata Dall'Oglio
Summary: This study conducted a literature review to identify instruments for assessing self-care in children and young adults with chronic conditions. A total of 11 instruments were identified, most of which focused on treatment adherence in self-care maintenance.
FRONTIERS IN PEDIATRICS
(2022)
Article
Psychology, Multidisciplinary
Kaitlin Venema, Bridgid Mariko Conn, Diane Tanaka, Karl Silge, Ellen Iverson
Summary: This study aims to understand the relationship between peer support, disclosure practices, and the quality of life and coping strategies of youth with chronic illnesses. The study found that participants who disclosed the psychological impact and concerns related to their condition tended to be female and had more friends to whom they disclosed. This group of participants also experienced higher levels of illness-related stress but engaged in more positive coping strategies.
CURRENT PSYCHOLOGY
(2023)
Article
Nursing
Jianing Hua, Xiaoliu Shi, Min Cui, Yuhua Xiao, Juan Xie, Guiling Geng
Summary: This study aims to develop a questionnaire on instrumental support for transitional care in older adults with chronic diseases and conduct a cross-sectional study through a mixed-method approach. Data will be collected from older adults with chronic diseases and experts from various fields, to help leaders identify areas for improvement in transitional care.
Article
Nursing
Abby Seydel, Nefeli Moutsoglou, Brandon M. Varilek, Mary Minton, Mary J. Isaacson
Summary: The purpose of this study was to explore nurses' experiences of communicating with patients and families at end of life (EOL). The findings revealed a theme of disharmony in the nurses' interactions with patients and families at EOL. This disharmony was further categorized into three sub-themes: navigating denial, the importance of words, and a knowledge deficit. It is crucial for nursing education to train and develop new graduates in the communication principles of primary palliative and EOL care to improve the quality of communication in the EOL experience for patients, families, and nurses.
JOURNAL OF HOSPICE & PALLIATIVE NURSING
(2022)