A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET

Ion Channels of the Sarcolemma and Intracellular Organelles in Duchenne Muscular Dystrophy: A Role in the Dysregulation of Ion Homeostasis and a Possible Target for Therapy

(2023) Mikhail V. Dubinin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cognitive impairment appears progressive in the mdx mouse

(2020) Emine Bagdatlioglu et al.   NEUROMUSCULAR DISORDERS

Microglial activation and tau burden predict cognitive decline in Alzheimer’s disease

(2020) Maura Malpetti et al.   BRAIN

Neuronal activity increases translocator protein (TSPO) levels

(2020) Tina Notter et al.   MOLECULAR PSYCHIATRY

Combining genetics, neuropsychology and neuroimaging to improve understanding of brain involvement in Duchenne muscular dystrophy – a narrative review

(2020) Nathalie Doorenweerd   NEUROMUSCULAR DISORDERS

Inhibition of TLR4 Induces M2 Microglial Polarization and Provides Neuroprotection via the NLRP3 Inflammasome in Alzheimer’s Disease

(2020) Weigang Cui et al.   Frontiers in Neuroscience

Molecular imaging of inflammation - Current and emerging technologies for diagnosis and treatment

(2020) Neil MacRitchie et al.   PHARMACOLOGY & THERAPEUTICS

[18F]FEPPA PET imaging for monitoring CD68-positive microglia/macrophage neuroinflammation in nonhuman primates

(2020) Matthew Zammit et al.   EJNMMI Research

Interleukin-6: A neuro-active cytokine contributing to cognitive impairment in Duchenne muscular dystrophy?

(2020) Kimberley A. Stephenson et al.   CYTOKINE

Neurocognitive Impairment in mdx Mice

(2019) Clarissa M. Comim et al.   MOLECULAR NEUROBIOLOGY

Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study

(2019) Jouni Tuisku et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity

(2019) Qingkun Liu et al.   NATURE IMMUNOLOGY

Cardiac Pathophysiology and the Future of Cardiac Therapies in Duchenne Muscular Dystrophy

(2019) Tatyana A. Meyers et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dystrophin deficiency leads to dysfunctional glutamate clearance in iPSC derived astrocytes

(2019) Abdulsamie M. Patel et al.   Translational Psychiatry

Dystrophin Dp71 and the Neuropathophysiology of Duchenne Muscular Dystrophy

(2019) Michael Naidoo et al.   MOLECULAR NEUROBIOLOGY

Assessment of TSPO in a Rat Experimental Autoimmune Myocarditis Model: A Comparison Study between [18F]Fluoromethyl-PBR28 and [18F]CB251

(2018) Ga Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Myocardial Inflammation Predicts Remodeling and Neuroinflammation After Myocardial Infarction

(2018) James T. Thackeray et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Glucose Metabolism as a Pre-clinical Biomarker for the Golden Retriever Model of Duchenne Muscular Dystrophy

(2018) Sarah Morar Schneider et al.   MOLECULAR IMAGING AND BIOLOGY

Molecular Imaging of Myocardial Inflammation With Positron Emission Tomography Post-Ischemia

(2018) James T. Thackeray et al.   JACC-Cardiovascular Imaging

In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18 F-FEDAA1106

(2018) Simon Cuhlmann et al.   Molecular Imaging

Role of Microglia TLRs in Neurodegeneration

(2018) Bernd L. Fiebich et al.   Frontiers in Cellular Neuroscience

A current approach to heart failure in Duchenne muscular dystrophy

(2017) Domenico D’Amario et al.   HEART

Routine 18F-FDG PET/CT does not detect inflammation in the left atrium in patients with atrial fibrillation

(2017) Philipp S. Lange et al.   INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING

Assessment of change in glucose metabolism in white matter of amyloid-positive patients with Alzheimer disease using F-18 FDG PET

(2017) Young Jin Jeong et al.   MEDICINE

[18F]FDG PET signal is driven by astroglial glutamate transport

(2017) Eduardo R Zimmer et al.   NATURE NEUROSCIENCE

ANG1 treatment reduces muscle pathology and prevents a decline in perfusion in DMD mice

(2017) Kelly M. Gutpell et al.   PLoS One

Dystrophic Cardiomyopathy—Potential Role of Calcium in Pathogenesis, Treatment and Novel Therapies

(2017) Victoria P. A. Johnstone et al.   Genes

Cognitive dysfunction in Duchenne muscular dystrophy: a possible role for neuromodulatory immune molecules

(2016) Mark G. Rae et al.   JOURNAL OF NEUROPHYSIOLOGY

Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study

(2016) M. Brendel et al.   JOURNAL OF NUCLEAR MEDICINE

Dystrophin-Deficient Cardiomyopathy

(2016) Forum Kamdar et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Role of neuroinflammation in neurodegenerative diseases (Review)

(2016) WEI-WEI CHEN et al.   Molecular Medicine Reports

Stroke in Duchenne Muscular Dystrophy

(2016) Martin Winterholler et al.   STROKE

A study on immunomodulatory mechanism of Polysaccharopeptide mediated by TLR4 signaling pathway

(2015) Zhixue Wang et al.   BMC IMMUNOLOGY

Skeletal Muscle Fibrosis in the mdx/utrn+/- Mouse Validates Its Suitability as a Murine Model of Duchenne Muscular Dystrophy

(2015) Kelly M. Gutpell et al.   PLoS One

Immune-mediated pathology in Duchenne muscular dystrophy

(2015) Amy S. Rosenberg et al.   Science Translational Medicine

Sex Differences in Translocator Protein 18 kDa (TSPO) in the Heart: Implications for Imaging Myocardial Inflammation

(2014) DeLisa Fairweather et al.   Journal of Cardiovascular Translational Research

Wasting mechanisms in muscular dystrophy

(2013) Jonghyun Shin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Increased blood–brain barrier vulnerability to systemic inflammation in an Alzheimer disease mouse model

(2013) Shuko Takeda et al.   NEUROBIOLOGY OF AGING

Neuropsychological and neurobehavioral functioning in Duchenne muscular dystrophy: A review

(2013) Wanda M. Snow et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Translocator Protein (18 kDa): A Promising Therapeutic Target and Diagnostic Tool for Cardiovascular Diseases

(2012) Xiaolong Qi et al.   Oxidative Medicine and Cellular Longevity

Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging

(2011) Ingrid E.C. Verhaart et al.   NEUROMUSCULAR DISORDERS

Myocardial inflammation in Duchenne Muscular Dystrophy as a precipitating factor for heart failure: a prospective study

(2010) Sophie Mavrogeni et al.   BMC Neurology

Duchenne Muscular Dystrophy: A 30-Year Population-Based Incidence Study

(2010) Joseph Dooley et al.   CLINICAL PEDIATRICS

A simple method for calculating power based on a prior trial

(2010) George F. Borm et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Glial dystrophin-associated proteins, laminin and agrin, are downregulated in the brain of mdx mouse

(2010) Beatrice Nico et al.   LABORATORY INVESTIGATION

Timeline of cardiac dystrophy in 3-18-month-old MDX mice

(2010) Christel Van Erp et al.   MUSCLE & NERVE

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management

(2009) Katharine Bushby et al.   LANCET NEUROLOGY

Functional Imaging of Inflammatory Diseases Using Nuclear Medicine Techniques

(2009) Sandip Basu et al.   SEMINARS IN NUCLEAR MEDICINE

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors

(2008) Alan A. Wilson et al.   NUCLEAR MEDICINE AND BIOLOGY