Article
Environmental Sciences
Zhiquan Liu, Yiming Li, Maria S. Sepulveda, Qichen Jiang, Yang Jiao, Qiang Chen, Yinying Huang, Jiangtao Tian, Yunlong Zhao
Summary: Nanoplastics have negative impacts on the reproduction of Daphnia pulex. Through analysis of proteome and molecular and biochemical evaluations, an adverse outcome pathway (AOP) for the toxicity of these contaminants has been proposed.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Engineering, Environmental
Zhiquan Liu, Yiming Li, Edgar Perez, Qichen Jiang, Qiang Chen, Yang Jiao, Yinying Huang, Ying Yang, Yunlong Zhao
Summary: This study used global transcriptome sequencing to investigate the impact of nanoplastic exposure on gene expression levels in Daphnia neonates, revealing key genes associated with oxidative stress, immune defense, and glycometabolism. Daphnia provides some molecular insights into nanoplastic toxicity, but further research on differentially expressed genes is needed to better understand the underlying mechanisms.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
P. E. Redondo-Hasselerharm, G. Vink, D. M. Mitrano, A. A. Koelmans
Summary: This study investigated the uptake and chronic effects of palladium-doped nanoplastics on freshwater amphipods. While a positive linear relationship between NP uptake and sediment concentration was observed, no significant effects were found on survival or growth of the amphipods. A biodynamic model showed bioaccumulation occurring in two kinetic compartments with a trophic transfer factor in the gut of 0.031. Using metal-doped plastics may offer opportunities for precise quantification of NP accumulation and exposure in risk assessment studies.
ENVIRONMENTAL SCIENCE-NANO
(2021)
Article
Biochemistry & Molecular Biology
Qinghai Cao, Wuyun Lv, Hong Jiang, Xueling Chen, Xinchao Wang, Yuchun Wang
Summary: In this study, a comprehensive identification and analysis of GSTs in tea plant were conducted, and their important roles in plant growth, development, and stress responses were revealed. The study found that CsGSTs were unevenly distributed across the tea plant genome and tandem duplication was the main driving force for their expansion. Furthermore, CsGSTs were found to respond to multiple stresses and exhibit different expression patterns in different tissues. CsGSTU19, localized in the nucleus and cell membrane, was proven to be involved in tea plant defense against temperature stresses and Co. camelliae infection.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Youfu Lin, Qi Xiao, Qianwen Hao, Zijin Qian, Xuexia Li, Peng Li, Hong Li, Lian Chen
Summary: This study investigated the role of Glutathione S-transferases (GSTs) in cold acclimation and cold stress-response mechanisms in the invasive snail P. canaliculata. A total of 30 PcGSTs were classified into seven classes and their expression patterns in different tissues were examined. RNA-seq analysis and qRT-PCR experiments revealed significant changes in expression levels of certain PcGST genes during cold acclimation, providing insights into the mechanisms underlying cold stress responses.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Warin Rangubpit, Eukote Suwan, Danai Sangthong, Kannika Wongpanit, Roger W. Stich, Prapasiri Pongprayoon, Sathaporn Jittapalapong
Summary: In this study, molecular dynamics simulations were conducted to investigate the binding of GTX and GSH to RmGST. It was found that GSH binds tighter and sits rigidly inside the G-site, while GTX occupies both active sites.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Xingang Li, Yuanting Pang, Yiwang Zhong, Zhandong Cai, Qibin Ma, Ke Wen, Hai Nian
Summary: In this study, a tau-like glutathione transferase family gene named GmGSTU23 was identified in soybean, which showed a concentration-time-specific expression pattern in response to salt stress. Transgenic lines with GmGSTU23 displayed enhanced salt tolerance, root length, and fresh weight compared to the wild type. Changes in glutathione pools and associated enzyme activity were observed, indicating that GmGSTU23 enhances the activity of glutathione transferase to scavenge reactive oxygen species and glutathione, thereby conferring enhanced tolerance to salt stress in plants.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Linlin Wang, Hongbo Fu, Juan Zhao, Jiagang Wang, Shuqi Dong, Xiangyang Yuan, Xiaorui Li, Mingxun Chen
Summary: This study conducted genome-wide identification and expression characteristics analysis of the GST gene family in foxtail millet. The results showed the presence of 73 GST genes (SiGSTs) divided into seven classes in the foxtail millet genome. The study provides a theoretical basis for identifying foxtail millet GST family information and improving their responses to different stresses.
Article
Biodiversity Conservation
Changan Ma, Di Zuo, Zhiquan Liu
Summary: This study cloned two Wnt genes (DpWnt4 and DpWnt16) from Daphnia pulex and investigated their sequences and expression patterns. The results showed that these two genes play important roles in regulating crustaceans and exhibit different response patterns to nanoplastics pollution.
Article
Biochemistry & Molecular Biology
Katie O'Rourke, Beatrice Engelmann, Rolf Altenburger, Ulrike Rolle-Kampczyk, Konstantinos Grintzalis
Summary: Pharmaceutical compounds, along with pesticides, heavy metals, and personal care products, are emerging contaminants that pose a major concern for aquatic ecosystems. The presence of pharmaceuticals can affect both freshwater organisms and human health through non-target effects and contamination of drinking water sources. This study explored the molecular and phenotypic alterations of commonly found pharmaceuticals in aquatic environments in daphnids, finding changes in enzyme activities and metabolic perturbations. Chronic exposure to low concentrations of pharmaceuticals resulted in significant alterations in metabolic and physiological endpoints.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biotechnology & Applied Microbiology
Swati Vaish, Reshma Parveen, Divya Gupta, Mahesh Kumar Basantani
Summary: Glutathione S-transferases (GSTs) are a multifunctional protein superfamily that plays important roles in various plant functions. In this study, 62 full-length GST genes belonging to nine GST classes were identified in the banana genome. These genes were distributed on 11 banana chromosomes and mainly located in the cytoplasm. Gene structure analysis showed conserved exon numbers and catalytic residues among different GST classes. Cis-regulatory element analysis revealed the dominance of light-responsive elements. RNA-seq data analysis indicated the involvement of MaGSTs in various stages of fruit development.
JOURNAL OF APPLIED GENETICS
(2022)
Article
Evolutionary Biology
Zhiqiang Ye, Xiaoqian Jiang, Michael E. Pfrender, Michael Lynch
Summary: The study on obligately asexual lineages reveals genetic expression differences between obligate parthenogens and cyclic parthenogens in a Daphnia pulex population, with the former having more allele-specific expression genes. Whole-genomic comparison also shows the presence of specific markers and functional differences in alleles coding for proteins involved in meiosis-related processes. These results provide insights into the genetic basis of transitioning to ameiotic parthenogenesis.
GENOME BIOLOGY AND EVOLUTION
(2021)
Article
Evolutionary Biology
Zhiqiang Ye, Xiaoqian Jiang, Michael E. Pfrender, Michael Lynch
Summary: Although obligately asexual lineages are widespread, little is known about the genetic elements underlying the origin and spread of obligate asexuality. In a study on a Daphnia pulex population, obligate parthenogens (OP) were found to have more allele-specific expression genes (ASEGs) compared to cyclical parthenogens (CP). Additionally, whole-genomic comparison revealed OP-specific markers and ASEGs, with some genes involved in meiosis-related processes showing functional differences between parental alleles.
GENOME BIOLOGY AND EVOLUTION
(2021)
Article
Agronomy
Yushi Jiang, Yuzhe Zhang, Ruijie Duan, Jiayi Fan, Peng Jiao, Hongji Sun, Shuyan Guan, Siyan Liu
Summary: ZmGST26 was found to be downregulated in maize under drought stress. Overexpression of ZmGST26 in Arabidopsis resulted in increased sensitivity to drought stress and ABA, as well as inhibited ABA-mediated stomatal closure. ZmGST26 overexpression decreased the resistance of Arabidopsis to drought stress and led to the accumulation of reactive oxygen species.
Article
Neurosciences
Bo Cheng, Xiaoliang Hong, Linfang Wang, Yuanyuan Cao, Dengli Qin, Han Zhou, Dianshuai Gao
Summary: Curzerene inhibits the progression of glioma by suppressing the expression of GSTA4 and matrix metalloproteinase 9, and inhibiting the activation of the mTOR pathway. It also induces apoptosis and reduces invasion and migration of glioma cells. In vivo studies have shown that Curzerene significantly inhibits tumor growth and prolongs survival time.
CNS NEUROSCIENCE & THERAPEUTICS
(2022)
Article
Chemistry, Multidisciplinary
Dicheng Xie, Wenchao Ma, Chao Wang, Weiping Zhang, Zhiying Ding
Summary: The viscosity of cell microenvironment affects cell physiological processes. A fluorescent probe X-V was designed to detect viscosity changes in a hepatic ischemia-reperfusion injury (HIRI) cell model with high selectivity and sensitivity. The probe has a fluorescence emission wavelength of 615 nm and a Stokes shift of up to 125 nm, making it useful for studying intracellular viscosity changes and cell viscosity changes in the HIRI cell model. Probe X-V provides a valuable tool for studying the relationship between mitochondrial viscosity and related diseases.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Ning Wei, Lulu Xu, Huimin Gong, Weiping Zhang, Dazhi Zhang, Shengjun Huang
Summary: Two protocols, sequential fluoride leaching-alkaline treatment and fluorination-alkaline treatment, are used to introduce mesoporosity in commercially available Al-rich mordenite zeolite. The sequential fluoride leaching-alkaline treatment successfully constructs intracrystalline mesopores, while the tandem fluorination-alkaline treatment does not. The different impacts of fluorination and fluoride leaching on mesoporosity development are closely associated with the alteration to the state of Al sites.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Physics, Fluids & Plasmas
Xiuxuan Duan, Shuoxue Jin, Yamin Song, Yanli Wang, Yi Xiong, Weiping Zhang, Shilei Li, Xingzhong Cao
Summary: The effect of pre-irradiation defects on helium trapping and diffusion behaviors was analyzed using a slow positron beam. Microscopic defects were observed in Si ion irradiated specimens. Low energy helium atoms could diffuse into deeper regions in metals without displacement damage. During the diffusion process, the helium atoms would be trapped by the Si-ion pre-irradiation defects. The formation of He-vacancy complexes affected the annihilation of positrons with electrons, leading to decreased S parameters. Shallow defects induced by 300 keV irradiation hindered helium diffusion more effectively than deep defects induced by 6 MeV irradiation. Therefore, pre-introduced defects can effectively trap helium atoms and hinder their diffusion.
Article
Optics
Dong Li, Chun-hua Yuan, Xiaoping Ma, Qingle Wang, Hwang Lee, Yao Yao, Weiping Zhang
Summary: We propose an alternative scheme for phase estimation in a Mach-Zehnder interferometer (MZI) with photon recycling, which achieves a higher phase sensitivity compared to the traditional MZI. Our scheme can achieve an enhancement factor of about 9.32 in phase sensitivity even with a 10% photon loss on the photon-recycled arm. Additionally, our scheme is able to achieve a lower quantum Cramer-Rao bound (QCRB) than the traditional scheme.
Article
Biodiversity Conservation
Chaoli Shi, Hongmei Yang, Mengxuan Xu, Tianyang Hua, Mengfan He, Yuchen Yang, Xiaoyu Hou, Hangjun Zhang, Zhiquan Liu
Summary: Two studies have shown that amphibian population declines are closely related to environmental pollution. One study found that perfluorooctane sulfonic acid (PFOS) was detected in 100% of amphibians and identified differentially expressed genes related to PFOS toxicity through transcriptome sequencing. After 21 days of PFOS exposure, 1441 genes showed differential expression, with 645 downregulated and 796 upregulated. These genes are involved in lipid metabolism, endocrine system, immune defense, and other functions and pathways. The toxicity of PFOS includes liver damage and even population decline. This research provides important molecular insights into the toxicity of PFOS.
Article
Nuclear Science & Technology
Weiping Zhang, Hui Liu, Yong Zhou, Kaixing Liao, Ying Huang
Summary: This paper employs molecular dynamics simulations to study the volume change and elastic property variation of aggregate-forming minerals in concrete. The results show that the densities of minerals with similar atomic structure and chemical composition vary in a similar trend with deposited energy due to the similar amorphization mechanism. After saturated irradiation, the elastic tensors of all silicate minerals are almost isotropic, while those of irradiated carbonate minerals remain anisotropic. Moreover, the elastic modulus ratio versus density ratio of irradiated minerals roughly follows the density-modulus scaling relationship. These findings can provide a basis for predicting the volume and elastic properties of irradiated concrete aggregates in nuclear facilities.
NUCLEAR ENGINEERING AND TECHNOLOGY
(2023)
Article
Physics, Multidisciplinary
Wenfeng Huang, Xinyun Liang, Baiqiang Zhu, Yuhan Yan, Chun-Hua Yuan, Weiping Zhang, L. Q. Chen
Summary: Interferometers play a crucial role in precision measurements and can be enhanced using quantum states to break the standard quantum limit (SQL). However, quantum states are easily degraded by losses. In this study, we designed a quantum interferometer with a variable beam splitter to protect the quantum resource from environmental impacts and achieved optimal phase sensitivity close to the quantum Cramer-Rao bound. This strategy can greatly reduce the quantum source requirements in quantum measurements and retain quantum advantages in lossy environments.
PHYSICAL REVIEW LETTERS
(2023)
Article
Computer Science, Information Systems
Sheng Ming, Jinxian Guo, Yuan Wu, Guzhi Bao, Shuhe Wu, Minwei Shi, Liqing Chen, Weiping Zhang
Summary: Optical quantum memory is a crucial component in the field of quantum technologies. In this study, the researchers demonstrated the optimization of Raman quantum memory using a new method called phase modulation. By applying this method, they achieved a total memory efficiency of 52.7%, which is a 13.3% improvement compared to the best case without phase modulation. The researchers also demonstrated a hybrid method combining phase and intensity modulations, which achieved a memory efficiency of 87.3%.
SCIENCE CHINA-INFORMATION SCIENCES
(2023)
Article
Chemistry, Physical
Panpan Gao, Yunyi He, Shihuan Lu, Mengfan He, Zhiqun Liu, Yang Deng, Zhiquan Liu, Ting Xu, Hangjun Zhang
Summary: A novel perovskite-type catalyst was developed for emergency removal of harmful algae in water. The results showed that La2CuO4/PMS system achieved significant removal efficiency of Microcystis aeruginosa cells (97%) and chlorophyll-a (100%) within 20 minutes without significant release of dissolved organic carbon and metals in water. The generation of & BULL;OH, SO4 & BULL;-, 1O2, and & BULL;O2- was responsible for algae inactivation and subsequent algal organic matters removal. The proposed heterogeneous catalytic mechanism suggested that La portion in La2CuO4 destabilized the cells by increasing zeta potential of algae suspension, while Cu portion facilitated electron transfer to improve the yields of & BULL;OH and SO4 & BULL;-. This study demonstrates that the new catalytic PMS process promises viable and effective control of harmful algal bloom impacts in water treatment.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2023)
Article
Engineering, Environmental
Hangjun Zhang, Yunyi He, Mengfan He, Qiyue Yang, Guoyi Ding, Yuanshuai Mo, Zhiquan Liu, Panpan Gao
Summary: This study constructed highly dispersed cobalt-modified cubic CaTiO3 perovskite for peroxymonosulfate (PMS) activation. The results showed that the surface Co2+/Co3+ redox couple and lattice oxygen were responsible for PMS activation, generating center dot OH, SO4 center dot-, and O-1(2). The study provides a novel strategy for catalyst synthesis in PMS activation for water treatment.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Plant Sciences
Rui-Peng Yu, Ye Su, Hans Lambers, Jasper van Ruijven, Ran An, Hao Yang, Xiao-Tong Yin, Yi Xing, Wei-Ping Zhang, Long Li
Summary: Resource complementarity enhances ecosystem functioning in diverse plant communities, and the role of facilitation in this process is poorly understood. This study used leaf manganese concentration as a proxy for rhizosheath carboxylate concentration and found that phosphorus facilitation mediated by the plasticity of root traits enhances the relative complementarity effect in low-phosphorus environments. The results support the vital mechanism of interspecific phosphorus facilitation via belowground processes and provide evidence for the pivotal role of phosphorus facilitation in biodiversity research.
Article
Chemistry, Physical
Peipei Xiao, Yong Wang, Kengo Nakamura, Yao Lu, Trees De Baerdemaeker, Andrei-Nicolae Parvulescu, Ulrich Muller, Dirk De Vos, Xiangju Meng, Feng-Shou Xiao, Weiping Zhang, Bernd Marler, Ute Kolb, Ryota Osuga, Maiko Nishibori, Hermann Gies, Toshiyuki Yokoi
Summary: The synthesis of efficient Cu-exchanged AEI zeolite catalyst is a crucial prerequisite for achieving continuous and efficient production of methanol from methane.
Article
Chemistry, Multidisciplinary
Ning Wei, Weiping Zhang, Dazhi Zhang, Shengjun Huang
Summary: The synergistic effect between hierarchical zeolites and alumina in the preparation of active Mo catalysts for the cross-metathesis reaction between ethene and 2-butene was demonstrated. The metathesis activity, as indicated by ethene conversion, increased from 24.1% to 49.2% with increasing alumina content in the composites from 10 wt% to 30 wt%. However, a further increase in alumina content led to a reduction in metathesis activity.
Article
Optics
Keye Zhang, Weijie Liang, Pierre Meystre, Weiping Zhang
Summary: Quantum particles performing Bloch oscillations in a spatially periodic potential can be used as accurate detectors of constant forces. Floquet-Bloch oscillations in the absence of a periodic lattice potential provide added flexibility and have various precision metrology applications, such as tachometers and magnetometers.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
