Review
Biochemistry & Molecular Biology
Chinmay Sharma, Tejas P. Singh, Shivshankar Thanigaimani, Domenico Nastasi, Jonathan Golledge
Summary: This study assessed the incidence rate of major adverse cardiovascular events (MACE) in patients with unrepaired abdominal aortic aneurysm (AAA) and their association with modifiable risk factors (diabetes, hypertension) and medication use (aspirin, statins). The study found a high incidence of cardiovascular death, myocardial infarction (MI), and stroke in patients with unrepaired AAA, but the prescription rate of preventive medication was suboptimal. Therefore, greater emphasis should be placed on secondary prevention measures in this population.
Review
Cardiac & Cardiovascular Systems
Adam Kramer, Leo E. Akioyamen, Seohyuk Lee, Alexandre Belanger, Isabelle Ruel, Lindsay Hales, Jacques Genest, Liam R. Brunham
Summary: This study aimed to assess the prevalence and age-of-onset of major adverse cardiovascular events (MACE) among patients with Homozygous Familial Hypercholesterolaemia (HoFH). The findings showed that atherosclerotic cardiovascular disease is common among HoFH patients and occurs at a young age. The age-of-onset of myocardial infarction was delayed by more than a decade from pre-1990 to post-1990, reflecting substantial progress in the management of this rare but severe disorder.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Dae Young Cheon, Kyungdo Han, Ye Seul Yang, Yerim Kim, Sang-Hwa Lee, Chulho Kim, Jong-Hee Sohn, Mi Sun Oh, Byung-Chul Lee, Minwoo Lee, Kyung-Ho Yu
Summary: This study found a significant association between migraines and major cardiovascular events, including myocardial infarction, ischemic stroke, and cardiovascular death, in individuals with type 2 diabetes. The presence of aura symptoms in migraines further increased the risk of myocardial infarction.
CARDIOVASCULAR DIABETOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Carlos Munoz-Bravo, Eva Soler-Iborte, Macarena Lozano-Lorca, Malak Kouiti, Carla Gonzalez-Palacios Torres, Rocio Barrios-Rodriguez, Jose Juan Jimenez-Moleon
Summary: The study aimed to investigate the association between serum copper levels (S-Cu) and the risk of major adverse cardiovascular events (MACE), and identify potential sources of results heterogeneity. The findings showed that high S-Cu levels were associated with an increased risk of total stroke, myocardial infarction, and cardiovascular mortality. Hybrid studies seemed to modify the strength of the association between S-Cu and the risk of cardiovascular mortality and ischemic stroke.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Medicine, General & Internal
Michael Nolde, Nayeon Ahn, Tobias Dreischulte, Evamaria Krause, Florian Guentner, Alexander Guenter, Roman Gerlach, Martin Tauscher, Ute Amann, Jakob Linseisen, Christa Meisinger, Sebastian-Edgar Baumeister, Ina-Maria Rueckert-Eheberg
Summary: This study evaluated the effect of proton pump inhibitors (PPIs) monotherapy on the risk of incident cardiovascular events and cardiovascular mortality. The results indicate that there is no significant association between PPI use and the risk of cardiovascular events and cardiovascular mortality after adjusting for observational study design bias and publication bias.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Dirk von Lewinski, Ewald Kolesnik, Faisal Aziz, Martin Benedikt, Norbert J. Tripolt, Markus Wallner, Peter N. Pferschy, Friederike von Lewinski, Nora Schwegel, Rury R. Holman, Abderrahim Oulhaj, Deddo Moertl, Jolanta Siller-Matula, Harald Sourij
Summary: Very early administration of SGLT2 inhibitors after acute myocardial infarction appears to be safe and effective in reducing NT-proBNP, as well as improving structural and functional left ventricular markers. There is no significant difference in severe adverse event rate between different initiation time groups.
CARDIOVASCULAR DIABETOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Yifang Zhou, Yidan Liu, Ruixiang Zeng, Wenjie Qiu, Yunhong Zhao, Yuanshen Zhou
Summary: This study found that early low-dose long-term colchicine can reduce the risk of major adverse cardiovascular events (MACE) in patients with acute myocardial infarction (AMI) through anti-inflammation, without leading to more gastrointestinal adverse events.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Clinical Neurology
Fardin Nabizadeh, Parya Valizadeh, Parisa Sharifi, Rasa Zafari, Omid Mirmosayyeb
Summary: This systematic review and meta-analysis suggest that Parkinson's disease is associated with a reduced risk of myocardial infarction, although the exact mechanism is unclear.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Raffaele Piccolo, Angelo Oliva, Marisa Avvedimento, Anna Franzone, Stephan Windecker, Marco Valgimigli, Giovanni Esposito, Peter Juni
Summary: Studies have shown that major and late bleeding in patients with coronary artery disease is associated with a similar increase in mortality compared to myocardial infarction, while early bleeding may have a stronger association with mortality.
Editorial Material
Physiology
Lixin Du, Jiao Qin, Dengchuan Wang, Yunhui Zhao, Ning Xu, Chaowen Wu, Jianpeng Yuan
Summary: The combination therapy of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1RA) shows significant benefits in reducing cardiovascular and death events among patients with type 2 diabetes.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Nutrition & Dietetics
Jiaqi Yang, Yulin Zhang, Xiaona Na, Ai Zhao
Summary: This study conducted a systematic review and meta-analysis on the associations between beta-carotene supplementation and cardiovascular disease (CVD) risk. The results showed that beta-carotene supplementation had no beneficial effects on CVD incidence and could potentially increase cardiovascular mortality. Smoking behavior was also found to be associated with increased cardiovascular incidence and mortality in the beta-carotene intervention group.
Article
Cardiac & Cardiovascular Systems
Zhongxing Cai, Haoyu Wang, Sheng Yuan, Dong Yin, Weihua Song, Kefei Dou
Summary: In patients with coronary artery ectasia, a high plasma big Endothelin-1 level is associated with an increased risk of major adverse cardiovascular events (MACE), improving risk stratification.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Medicine, General & Internal
Daniele Pastori, Danilo Menichelli, Arianna Di Rocco, Alessio Farcomeni, Angela Sciacqua, Pasquale Pignatelli, Laurent Fauchier, Gregory Y. H. Lip
Summary: Atrial fibrillation (AF) patients with cancer have a higher risk of bleeding, but the risk of cardiovascular events is not significant.
INTERNAL AND EMERGENCY MEDICINE
(2022)
Article
Medicine, General & Internal
Marco Pasi, Gregoire Boulouis, Arnaud Bisson, Julien Herbert, Alexandre Bodin, Charlotte Cordonnier, Gregory Y. H. Lip, Laurent Fauchier
Summary: Adverse cardiovascular events are more frequent in survivors of non-traumatic intracranial hemorrhage (ICrH) compared to survivors of ischemic stroke (IS), especially in those with atrial fibrillation (AF).
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Samuel S. Gidding, Laura A. Colangelo, Chike C. Nwabuo, Cora E. Lewis, David R. Jacobs, Pamela J. Schreiner, Joao A. C. Lima, Norrina B. Allen
Summary: The PDAY risk score based on post-mortem measurements was found to be highly predictive of future ASCVD events in young adults. The presence of coronary artery calcium improved risk prediction only if the score was 0. Cumulative risk exposure and PDAY score at age 18-30 were also significant factors for predicting ASCVD.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Gabriela Lima de Melo Ghisi, Andree-Anne Hebert, Paul Oh, Tracey Colella, Crystal Aultman, Carolina Carvalho, Rajni Nijhawan, Marie-Kristelle Ross, Sherry L. Grace
Summary: This study aimed to co-design women-focused cardiac rehabilitation (CR) education to meet their specific needs. Through literature review, needs assessment, and content development, the research team created open-access educational resources including videos and slide decks. These resources will be used to support women in reducing their risk of cardiovascular sequelae.
Article
Cardiac & Cardiovascular Systems
Hannah Spielmann, Wolfgang Albert, Sandra Semmig-Koenze, Volker Lauenroth, Christine Spitz-Koeberich, Paulina Staus, Katharina Tigges-Limmer, Christiane Kugler, S. E. L. M. A. Study SELMA Study Grp
Summary: This study investigated the construct of psychosocial adjustment and the role of social support in patients with durable VAD support. The results showed that the majority of the participants reported high levels of perceived social support and good psychosocial adjustment. Higher levels of perceived social support were associated with lower levels of anxiety and depression, and higher levels of quality of life.
Article
Cardiac & Cardiovascular Systems
Tania T. Von Visger, Ji Won Shin, Mary Beth Happ
Summary: This study explores the perspectives of Urban Zen Integrative Therapy interventionists on the delivery of the therapy, aiming to gain a deeper understanding of subjective variables that may influence intervention fidelity. The results reveal several key themes related to adherence to the intervention delivery, such as balancing between tailoring and standardization, challenges faced during delivery, the need for teamwork, and clients' application of the therapy.
Review
Cardiac & Cardiovascular Systems
Dejina Thapa, Sek Ying Chair, Mei Sin Chong, Rishi Ram Poudel, Tenaw Gualau Melesse, Kai Chow Choi, Hon Lon Tam
Summary: The ventilator bundle has been found to effectively reduce the incidence of ventilator-associated pneumonia and improve related outcomes. However, caution should be exercised in interpreting these findings due to the low-to-moderate certainty of evidence and high heterogeneity.
Article
Cardiac & Cardiovascular Systems
Jianxiong Lai, Bin Fang, Lirong Luo, Wenjie Xie, Yuanhui Xu, Jian Li
Summary: This study used two-sample bidirectional mendelian randomization to explore the causal link between asthma and inflammatory bowel disease. The researchers found a negative correlation between asthma and Crohn's disease. However, further research is needed to confirm this finding.
Article
Cardiac & Cardiovascular Systems
Eriadina Alves Lima, Gezabell Rodrigues, Beatriz Carneiro Mota, Shamyr Sulyvan Castro, Rafael Barreto Mesquita, Camila Ferreira Leite
Summary: This study investigated the components of the International Classification of Functioning, Disability and Health (ICF) reflected in the assessment instruments used in cardiac rehabilitation for individuals with heart failure (HF). The results showed that body function was the most frequently detected component, but none of the instruments covered all aspects of the ICF. The Minnesota Living with Heart Failure Questionnaire (MLHFQ) demonstrated the most comprehensive coverage of ICF components.
Review
Cardiac & Cardiovascular Systems
Baolu Yang, Leyi Gao, Zhaohui Tong
Summary: The use of sedative and analgesic medications during non-invasive ventilation can reduce the risk of tracheal intubation and delirium in patients with acute respiratory failure. Among the different medications, dexmedetomidine showed better clinical outcomes, especially when closely monitoring the patients' vital signs.
Article
Cardiac & Cardiovascular Systems
Liu Huang, Mengtao Song, Ling Wang, Qiran Zhang, Xiao Liu, Chunfeng Cai
Summary: This study examines the reliability and validity of the Chinese Interoceptive Awareness Questionnaire (C-IAQ) for Chinese cardiovascular disease (CVD) patients. The results indicate that the C-IAQ has favorable psychometric features and can be used to measure the interoceptive awareness of CVD patients.
Review
Cardiac & Cardiovascular Systems
Qiuxia Zhang, Khuan Lee, Zawiah Mansor, Iskasymar Ismail, Yi Guo, Qiao Xiao, Poh Ying Lim
Summary: This study conducted a systematic review to understand the effect of rapid response teams (RRT) on patient outcomes. The results showed that, despite variation in context and intervention type, most studies demonstrated that RRT positively impacts patient outcomes.
Article
Cardiac & Cardiovascular Systems
Sikandar H. Khan, Anthony J. Perkins, Samreen Jawaid, Sophia Wang, Heidi Lindroth, Rebecca E. Schmitt, Jason Doles, Jason D. True, Sujuan Gao, Gideon A. Caplan, Homer L. Twigg III, Kenneth Kesler, Babar A. Khan
Summary: This study aimed to identify protein pathways associated with delirium post-esophagectomy. The findings revealed that coagulation factor IX and mannosyl-oligosaccharide 1,2-alpha-mannosidase were associated with delirium, while complement C2 and mannosyl-oligosaccharide 1,2-alpha-mannosidase were associated with delirium severity.
Review
Cardiac & Cardiovascular Systems
Hua Li, Tao Dong, Jinling Luan
Summary: Fluticasone propionate and salmeterol (FSC) are viable options for step-up treatment in asthmatic children, as they can reduce the incidence of asthma exacerbations and improve lung function. FSC treatment for more than 12 weeks shows a greater likelihood of reducing asthma exacerbations and decreasing the use of albuterol. There were no significant differences in drug-related adverse events between FSC and fluticasone propionate (FP) alone.
Article
Cardiac & Cardiovascular Systems
Harrison Krebs, Kimberly Crutcher, Yan Su, Marilyn A. Prasun
Summary: During the COVID pandemic, patients experienced increased depression and poorer quality of life. However, significant improvements were observed in all outcomes following completion of Cardiac Rehabilitation (CR).
Article
Cardiac & Cardiovascular Systems
Hong-Lin Wu, Si-Jia Zhou, Xiu-Hua Chen, Hua Cao, Yi-Rong Zheng, Qiang Chen
Summary: This study aimed to evaluate the value of LUS score at VA-ECMO withdrawal in neonatal ARDS patients. The results showed that LUS score significantly improved during VA-ECMO treatment and could be used to evaluate various lung diagnostic signs. Additionally, LUS score was positively correlated with ECMO blood flow and could predict ECMO weaning success.
Article
Cardiac & Cardiovascular Systems
Lingyu Lin, Yanchun Peng, Xizhen Huang, Sailan Li, Liangwan Chen, Yanjuan Lin
Summary: This study aimed to investigate the effects of family intervention on the incidence of postoperative delirium (POD) and ICU prognoses of patients undergoing cardiac valve surgery. The results showed that family intervention could reduce the incidence of POD, shorten ICU stays, reduce the incidence of anxiety and depression in family caregivers, and improve their satisfaction. Therefore, family intervention is of significant importance for patients undergoing cardiac valve surgery.
