Review
Oncology
Giorgio Bogani, Giuseppe Sarpietro, Gabriella Ferrandina, Valerio Gallotta, Violante Di Donato, Antonino Ditto, Ciro Pinelli, Jvan Casarin, Fabio Ghezzi, Giovanni Scambia, Francesco Raspagliesi
Summary: ERAS is a pathway designed to promote early recovery for patients undergoing major surgery, with three important components: preoperative, intraoperative, postoperative program. Adoption of ERAS can lead to lower complication rates, shorter hospital stays, improved patient outcomes, and reduced overall cost of care.
Review
Oncology
S. P. Bisch, C. A. Jago, E. Kalogera, H. Ganshorn, L. A. Meyer, P. T. Ramirez, S. C. Dowdy, G. Nelson
Summary: ERAS implementation in gynecologic oncology surgery leads to decreased length of stay, complications, and cost, without increasing readmission or mortality rates.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Oncology
Stephanie Alimena, Parisa Fallah, Briana Stephenson, Colleen Feltmate, Sarah Feldman, Kevin M. Elias
Summary: The study aimed to compare differences in ERAS implementation and outcomes by race. It found that fewer non-white women received preadmission education, possibly due to language barriers. However, there were no differences in ERAS compliance, postoperative complications, readmissions, reoperations, and ICU transfers between different races.
GYNECOLOGIC ONCOLOGY
(2023)
Article
Clinical Neurology
Bertrand Debono, Thomas W. Wainwright, Michael Y. Wang, Freyr G. Sigmundsson, Michael M. H. Yang, Henriette Smid-Nanninga, Aurelien Bonnal, Jean -Charles Le Huec, William J. Fawcett, Olle Ljungqvist, Guillaume Lonjon, Hans D. de Boer
Summary: ERAS protocols have shown significant improvements in outcomes by optimizing patient care pathways, reducing complications, enhancing patient experience, and shortening hospital stays. A multidisciplinary consensus review on lumbar fusion surgery with ERAS program was conducted, resulting in 28 recommendations covering various aspects of preoperative, intraoperative, and postoperative care.
Review
Medicine, General & Internal
Janita Pak Chun Chau, Xu Liu, Suzanne Hoi Shan Lo, Wai Tong Chien, Sze Ki Hui, Kai Chow Choi, Jie Zhao
Summary: Based on the analysis of 7 randomized controlled trials, the study found that perioperative enhanced recovery after surgery (ERAS) programs in gynecological cancer care may reduce length of postoperative hospital stay, decrease readmission rates, and facilitate postoperative bowel function recovery without compromising participant safety. However, due to limited methodological quality, further research is required to validate the reliability of these findings.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2022)
Article
Oncology
Steven P. Bisch, Gregg Nelson
Summary: Enhanced Recovery After Surgery (ERAS) is a global surgical quality improvement program that has been shown to improve clinical outcomes and reduce costs by implementing evidence-based recommendations in various specialties.
Article
Immunology
Raffaele Brustia, Antoine Monsel, Stefano Skurzak, Eduardo Schiffer, Francois Martin Carrier, Damiano Patrono, Abdourahamane Kaba, Olivier Detry, Luiz Malbouisson, Wellington Andraus, Franck Vandenbroucke-Menu, Gianni Biancofiore, Toshimi Kaido, Philippe Compagnon, Shinji Uemoto, Gonzalo Rodriguez Laiz, Marieke De Boer, Susan Orloff, Paola Melgar, Carlijn Buis, Miriam Zeillemaker-Hoekstra, Helen Usher, Koen Reyntjens, Emily Baird, Nicolas Demartines, Stephen Wigmore, Olivier Scatton
Summary: This study presents the specific ERAS Society recommendations for liver transplantation (LT) based on the best available evidence and expert consensus. Screening and treatment for malnutrition in patients are recommended. Prophylactic nasogastric intubation and abdominal drainage may be omitted, and early extubation should be considered. Early oral intake, mobilization, and multimodal-balanced analgesia are also recommended.
Review
Oncology
Christa Aubrey, Gregg Nelson
Summary: Enhanced recovery after surgery (ERAS) has established benefits in minimally invasive gynecologic oncology surgery, including decreased length of stay, cost-savings, decreased opioid use, and increased patient satisfaction.
Review
Oncology
Javier Ripolles-Melchor, Ane Abad-Motos, Andres Zorrilla-Vaca
Summary: This review focuses on the rationale and oncologic outcomes of the application of Enhanced Recovery After Surgery (ERAS) protocols in adult patients undergoing major surgery. It was found that the implementation of ERAS protocols is associated with fewer postoperative complications and decreased return to intended oncologic treatment (RIOT). However, there is limited research on the influence of ERAS application on long-term oncologic outcomes.
CURRENT ONCOLOGY REPORTS
(2022)
Article
Obstetrics & Gynecology
Natalia R. Gomez-Hidalgo, Andrei Pletnev, Zoia Razumova, Nicolo Bizzarri, Ilker Selcuk, Charalampos Theofanakis, Kamil Zalewski, Tanja Nikolova, Maximilian Lanner, Joanna Kacperczyk-Bartnik, Houssein El Hajj, Assumpcio Perez-Benavente, Gregg Nelson, Antonio Gil-Moreno, Christina Fotopoulou, Jose Luis Sanchez-Iglesias
Summary: The survey revealed widespread implementation of ERAS protocols across Europe, but with varying degrees of adherence to different aspects of the protocol items.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Oncology
Alon D. Altman, Alexandre Rozenholc, Lana Saciragic, Xiao-qing Liu, Gregg Nelson
Summary: This study surveyed the implementation of Enhanced Recovery After Surgery (ERAS) guidelines among gynecologic oncology providers in Canada. The results showed an increased uptake of 10 ERAS guideline recommendations, indicating potential improvements in clinical outcomes and healthcare system-level benefits.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2022)
Review
Medicine, General & Internal
Ting Chen, Huaping Wei, Weigang Yue, Yan Su, Xiaoyan Fu
Summary: This study aims to evaluate the efficacy and safety of ERAS in patients with lung cancer. A systematic review will be conducted by searching eight databases and conducting a meta-analysis. The results of this study will be published in a peer-reviewed journal.
Review
Oncology
Gregg Nelson
Summary: The purpose of this review is to provide an overview of the current state of research on enhanced recovery after surgery (ERAS) in gynecologic oncology. Over the past 5 years, there has been increasing evidence supporting the use of ERAS in gynecologic oncology surgery. However, surveys have shown that ERAS uptake is not optimal, and implementing ERAS can be challenging. This review discusses the core components necessary for successful ERAS implementation, as well as specific developments in gynecologic oncology, such as same-day discharge initiatives and the use of telemedicine.
CURRENT ONCOLOGY REPORTS
(2023)
Review
Surgery
Erik Stenberg, Luiz Fernando dos Reis Falcao, Mary O'Kane, Ronald Liem, Dimitri J. Pournaras, Paulina Salminen, Richard D. Urman, Anupama Wadhwa, Ulf O. Gustafsson, Anders Thorell
Summary: This article presents the second updated guideline from the Enhanced Recovery After Surgery (ERAS) Society, providing a consensus and recommendations for optimal perioperative care in bariatric surgery. Through a comprehensive evaluation of literature, evidence-based consensus was achieved.
WORLD JOURNAL OF SURGERY
(2022)
Article
Oncology
Emily M. Ko, Diego Aviles, Nathanael C. Koelper, Mark A. Morgan, Lori Cory
Summary: This study found that past abdominopelvic surgeries are associated with worse perioperative outcomes in women undergoing hysterectomy. Previous surgeries likely to cause adhesive disease were linked to longer hospital stays, increased blood loss, and higher readmission rates.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Oncology
Eun-Young Kang, Ashley Weir, Nicola S. Meagher, Kyo Farrington, Gregg S. Nelson, Prafull Ghatage, Cheng-Han Lee, Marjorie J. Riggan, Adelyn Bolithon, Gordana Popovic, Betty Leung, Katrina Tang, Neil Lambie, Joshua Millstein, Jennifer Alsop, Michael S. Anglesio, Beyhan Ataseven, Ellen Barlow, Matthias W. Beckmann, Jessica Berger, Christiani Bisinotto, Hans Boesmueller, Jessica Boros, Alison H. Brand, Angela Brooks-Wilson, Sara Y. Brucker, Michael E. Carney, Yovanni Casablanca, Alicia Cazorla-Jimenez, Paul A. Cohen, Thomas P. Conrads, Linda S. Cook, Penny Coulson, Madeleine Courtney-Brooks, Daniel W. Cramer, Philip Crowe, Julie M. Cunningham, Cezary Cybulski, Kathleen M. Darcy, Mona A. El-Bahrawy, Esther Elishaev, Ramona Erber, Rhonda Farrell, Sian Fereday, Anna Fischer, Maria J. Garcia, Simon A. Gayther, Aleksandra Gentry-Maharaj, C. Blake Gilks, Marcel Grube, Paul R. Harnett, Shariska Petersen Harrington, Philipp Harter, Arndt Hartmann, Jonathan L. Hecht, Sebastian Heikaus, Alexander Hein, Florian Heitz, Joy Hendley, Brenda Y. Hernandez, Susanna Hernando Polo, Sabine Heublein, Akira Hirasawa, Estrid Hogdall, Claus K. Hogdall, Hugo M. Horlings, David G. Huntsman, Tomasz Huzarski, Andrea Jewell, Mercedes Jimenez-Linan, Michael E. Jones, Scott H. Kaufmann, Catherine J. Kennedy, Dineo Khabele, Felix K. F. Kommoss, Roy F. P. M. Kruitwagen, Diether Lambrechts, Nhu D. Le, Marcin Lener, Jenny Lester, Yee Leung, Anna Linder, Liselore Loverix, Jan Lubinski, Rashna Madan, G. Larry Maxwell, Francesmary Modugno, Susan L. Neuhausen, Alexander Olawaiye, Siel Olbrecht, Sandra Orsulic, Jose Palacios, Celeste Leigh Pearce, Malcolm C. Pike, Carmel M. Quinn, Ganendra Raj Mohan, Cristina Rodriguez-Antona, Matthias Ruebner, Andy Ryan, Stuart G. Salfinger, Naoko Sasamoto, Joellen M. Schildkraut, Minouk J. Schoemaker, Mitul Shah, Raghwa Sharma, Yurii B. Shvetsov, Naveena Singh, Gabe S. Sonke, Linda Steele, Colin J. R. Stewart, Karin Sundfeldt, Anthony J. Swerdlow, Aline Talhouk, Adeline Tan, Sarah E. Taylor, Kathryn L. Terry, Aleksandra Toloczko, Nadia Traficante, Koen K. Van de Vijver, Maaike A. van der Aa, Toon Van Gorp, Els Van Nieuwenhuysen, Lilian Van-Wagensveld, Ignace Vergote, Robert A. Vierkant, Chen Wang, Lynne R. Wilkens, Stacey J. Winham, Anna H. Wu, Javier Benitez, Andrew Berchuck, Francisco J. Candido Dos Reis, Anna DeFazio, Peter A. Fasching, Ellen L. Goode, Marc T. Goodman, Jacek Gronwald, Beth Y. Karlan, Stefan Kommoss, Usha Menon, Hans-Peter Sinn, Annette Staebler, James D. Brenton, David D. Bowtell, Paul D. P. Pharoah, Susan J. Ramus, Martin Kobel
Summary: This study validates that high-level amplification of CCNE1 is associated with shorter survival in tubo-ovarian high-grade serous carcinoma (HGSC), supporting its use as a prognostic biomarker in this disease.
Article
Oncology
Citadel J. J. Cabasag, Melina Arnold, Mark Rutherford, Jacques Ferlay, Aude Bardot, Eileen Morgan, John Butler, Dianne L. L. O'Connell, Gregg Nelson, Claus Hogdall, Tine Schnack, Anna Gavin, Mark Elwood, Louise Hanna, Charlie Gourley, Prithwish De, Nathalie Saint-Jacques, Lina Steinrud Morch, Ryan R. Woods, Alon D. D. Altman, Peter Sykes, Paul A. A. Cohen, Orla McNally, Bjorn Moller, Paul Walsh, David S. S. Morrison, Freddie Bray, Isabelle Soerjomataram
Summary: The aim of this study was to assess the incidence and survival trends of epithelial ovarian cancer (EOC) by histological subtype across seven high-income countries. Data from 1995 to 2014 were obtained from 20 cancer registries, and results showed that there was a significant increase in serous carcinoma incidence among women aged 65 to 99 years. On the other hand, the incidence of adenocarcinoma not otherwise specified showed a marked decrease in women aged 15 to 64 years. The overall survival of EOC has improved over the 20-year study period in all countries.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Oncology
Jenna Shirley, Pascal Lambert, Mark W. Nachtigal, Alon D. Altman
Summary: This study assesses the documentation of elements in the OCPCDE checklist in synoptic reports (SRs) and dictated reports (DRs) for suspected epithelial ovarian cancer surgery. The SRs were found to include more data elements, indicating their completeness and importance. It is recommended to continue using SRs in our department and implement synoptic reporting in other gynecologic oncology centers.
GYNECOLOGIC ONCOLOGY
(2023)
Article
Genetics & Heredity
Selina Casalino, Sharon Bruce, Kim Serfas, Alon D. Altman, Sarah Kean, Pascal Lambert, Kirk J. McManus, Jessica N. Hartley, Mark W. Nachtigal
Summary: Individuals with pathogenic variants in BRCA1 or BRCA2 have an increased risk of developing high-grade serous ovarian cancer. Risk-reducing salpingo-oophorectomy (RRSO) is recommended for these individuals to preventatively remove their ovaries and fallopian tubes. The Hereditary Gynecology Clinic (HGC) in Winnipeg, Canada provides specialized care for BRCA-positive individuals. A study was conducted to explore the decision-making processes and experiences of these individuals at the HGC. The study found that the HGC played a supporting role in decision-making, and a novel framework was proposed to consolidate the various influences and implications of RRSO in the context of the HGC.
JOURNAL OF GENETIC COUNSELING
(2023)
Review
Surgery
Tamir N. Sholklapper, Jorge Ballon, Aref S. Sayegh, Anibal La Riva, Laura C. Perez, Sherry Huang, Michael Eppler, Gregg Nelson, Giovanni Marchegiani, Robert Hinchliffe, Luca Gordini, Marc Furrer, Michael J. Brenner, Salome Dell-Kuster, Chandra Shekhar Biyani, Nader Francis, Haytham M. A. Kaafarani, Matthias Siepe, Des Winter, Julie A. Sosa, Francesco Bandello, Robert Siemens, Jochen Walz, Alberto Briganti, Christian Gratzke, Andre L. Abreu, Mihir M. Desai, Rene Sotelo, Riaz Agha, Keith D. Lillemoe, Steven Wexner, Gary S. Collins, Inderbir Gill, Giovanni E. Cacciamani
Summary: This study assesses the prevalence and typology of perioperative adverse event reporting guidelines among surgery and anesthesiology journals. Results show that 46.5% of the queried journals recommend surgical adverse event reporting. Journals in the surgery, urology, and anesthesia categories are most likely to recommend reporting; those in the top SJR quartiles and based in Western Europe, North America, and the Middle East are also more likely to recommend.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Article
Surgery
Claire Temple-Oberle, Spencer Yakaback, Carmen Webb, Golpira Elmi Assadzadeh, Gregg Nelson
Summary: This randomized clinical trial compared the quality of recovery and patient satisfaction between conventional in-person follow-up and smartphone app-assisted follow-up for patients undergoing breast reconstruction and gynecologic oncology surgery. The results showed that smartphone app-assisted follow-up led to improved quality of recovery compared to conventional in-person follow-up, with equal patient satisfaction.
Article
Oncology
Sabrina Piedimonte, Limor Helpman, Gregory Pond, Gregg Nelson, Janice Kwon, Alon Altman, Tomer Feigenberg, Laurie Elit, Susie Lau, Jeanelle Sabourin, Vanessa Samouelian, Karla Willows, Christa Aubrey, Ji-Hyun Jang, Ly-Ann Teo -Fortin, Norah Cockburn, Nora -Beth Saunders, Sarah Shamiya, Danielle Vicus, Marie Plante
Summary: This study aimed to determine whether close and positive surgical margins are associated with surgical approach and survival. The results showed that the surgical approach was not associated with margin status, but close margins were associated with a higher risk of death. Minimally invasive surgery was also associated with worse survival, suggesting that margin status may not be the main driver of worse survival in these cases.
GYNECOLOGIC ONCOLOGY
(2023)
Article
Oncology
Cristina Mitric, Sarah Daisy Kosa, Soyoun Rachel Kim, Gregg Nelson, Stephane Laframboise, Genevieve Bouchard-Fortier
Summary: The implementation of a peri-operative care program based on enhanced recovery after surgery principles for minimally invasive gynecologic oncology surgery led to an improvement in same day discharge rate and significant reductions in overall costs and some surgical and post-operative visit costs.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2023)
Article
Oncology
Anastasios Pandraklakis, Dimitrios Haidopoulos, Theodoros Lappas, Emmanouil Stamatakis, Dimitrios Valsamidis, Maria D. Oikonomou, Dimitrios Loutradis, Alexandros Rodolakis, Steven P. Bisch, Gregg Nelson, Nikolaos Thomakos
Summary: This study evaluated the safety and effectiveness of thoracic epidural analgesia in gynecologic oncology patients undergoing laparotomy as part of the enhanced recovery after surgery (ERAS) multimodal analgesic protocol. The results showed that thoracic epidural analgesia provided better pain relief and additional benefits during the peri-operative period, improving the overall recovery experience of patients with gynecologic cancer.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2023)
Review
Oncology
Gregg Nelson
Summary: The purpose of this review is to provide an overview of the current state of research on enhanced recovery after surgery (ERAS) in gynecologic oncology. Over the past 5 years, there has been increasing evidence supporting the use of ERAS in gynecologic oncology surgery. However, surveys have shown that ERAS uptake is not optimal, and implementing ERAS can be challenging. This review discusses the core components necessary for successful ERAS implementation, as well as specific developments in gynecologic oncology, such as same-day discharge initiatives and the use of telemedicine.
CURRENT ONCOLOGY REPORTS
(2023)
Article
Oncology
Jose Luis Sanchez-Iglesias, Natalia R. Gomez-Hidalgo, Vicente Bebia, Jose Manuel Ramirez, Asuncion Perez-Benavente, Gregg Nelson, Antonio Gil-Moreno
Summary: A retrospective study found that mechanical bowel preparation (MBP) was not associated with any specific benefit for advanced ovarian cancer surgery, and it is recommended for gynecologic oncologists to consider discontinuing this practice.
CLINICAL & TRANSLATIONAL ONCOLOGY
(2023)
Article
Oncology
Christa Aubrey, Gregory R. Pond, Limor Helpman, Danielle Vicus, Laurie Elit, Marie Plante, Susie Lau, Janice S. Kwon, Alon D. Altman, Karla Willows, Tomer Feigenberg, Jeanelle Sabourin, Vanessa Samouelian, Laurence Bernard, Norah Cockburn, Nora-Beth Saunders, Sabrina Piedimonte, Ly-Ann Teo-Fortin, Soyoun Rachel Kim, Noor Sadeq, Ji-Hyun Jang, Sarah Shamiya, Gregg Nelson
Summary: Minimally invasive surgery for macroscopic cervical cancer leads to worse outcomes than open surgery, but preoperative conization may help mitigate the risk. This retrospective study examined oncologic outcomes in cervical cancer cases treated initially with conization and subsequent hysterectomy using either minimally invasive or open approaches. The study found no significant differences in recurrence-free survival or overall survival between the two surgical approaches. However, further studies are needed to confirm these findings.
Letter
Anesthesiology
Sylvie Bowden, Gabrielle Wagner, Cindy Xue, Gregg Nelson, Amy Metcalfe
CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE
(2023)