Interactions of glial cells with neuronal synapses, from astrocytes to microglia and oligodendrocyte lineage cells

Inhibition of glial D‐serine release rescues synaptic damage after brain injury

(2022) Stephen A. Tapanes et al.   GLIA

The S1PR2‐CCL2‐BDNF‐TrkB pathway mediates neuroinflammation and motor incoordination in hyperammonaemia

(2022) Yaiza M. Arenas et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior

(2022) Li-Pao Fang et al.   Nature Communications

Astrocytes in Post-traumatic Stress Disorder

(2022) Baoman Li et al.   Neuroscience Bulletin

Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development

(2022) Yajun Xie et al.   Cell Reports

Oligodendrocyte precursor cells engulf synapses during circuit remodeling in mice

(2022) Yohan S. S. Auguste et al.   NATURE NEUROSCIENCE

Hippocampal astrocytes modulate anxiety-like behavior

(2022) Woo-Hyun Cho et al.   Nature Communications

Astrocytes in Chronic Pain: Cellular and Molecular Mechanisms

(2022) Huan-Jun Lu et al.   Neuroscience Bulletin

Reconstruction of motor control circuits in adult Drosophila using automated transmission electron microscopy

(2021) Jasper S. Phelps et al.   CELL

Microglial deletion and inhibition alleviate behavior of post-traumatic stress disorder in mice

(2021) Shuoshuo Li et al.   Journal of Neuroinflammation

Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea

(2021) Yunfeng Hua et al.   Cell Reports

Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cells

(2021) Xitiz Chamling et al.   Nature Communications

Microglial MERTK eliminates phosphatidylserine‐displaying inhibitory post‐synapses

(2021) Jungjoo Park et al.   EMBO JOURNAL

Hippocampal astrocytic neogenin regulating glutamate uptake, a critical pathway for preventing epileptic response

(2021) Dong Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration

(2021) Xin Ding et al.   Nature Communications

Oligodendroglial GABAergic Signaling: More Than Inhibition!

(2021) Xianshu Bai et al.   Neuroscience Bulletin

Co-targeting myelin inhibitors and CSPGs markedly enhances regeneration of GDNF-stimulated, but not conditioning-lesioned, sensory axons into the spinal cord

(2021) Jinbin Zhai et al.   eLife

PSD-93 up-regulates the synaptic activity of corticotropin-releasing hormone neurons in the paraventricular nucleus in depression

(2021) Xin-Ya Qin et al.   ACTA NEUROPATHOLOGICA

GABA-receptive microglia selectively sculpt developing inhibitory circuits

(2021) Emilia Favuzzi et al.   CELL

Astrocyte-neuron metabolic cooperation shapes brain activity

(2021) Gilles Bonvento et al.   Cell Metabolism

Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS

(2021) Travis E. Faust et al.   NATURE REVIEWS NEUROSCIENCE

Impaired calcium signaling in astrocytes modulates autism spectrum disorder-like behaviors in mice

(2021) Qian Wang et al.   Nature Communications

Obesity-induced astrocyte dysfunction impairs heterosynaptic plasticity in the orbitofrontal cortex

(2021) Benjamin K. Lau et al.   Cell Reports

Astrocytes Render Memory Flexible by Releasing D-Serine and Regulating NMDA Receptor Tone in the Hippocampus

(2021) Wuhyun Koh et al.   BIOLOGICAL PSYCHIATRY

Astrocyte Ca 2+ -evoked ATP release regulates myelinated axon excitability and conduction speed

(2021) Jonathan Lezmy et al.   SCIENCE

Voltage compartmentalization in dendritic spines in vivo

(2021) Victor Hugo Cornejo et al.   SCIENCE

Extrasynaptic therapeutic targets in substance use and stress disorders

(2021) Ritchy Hodebourg et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety

(2021) Xiao Zhang et al.   Nature Communications

Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation

(2020) Roberta Marisca et al.   NATURE NEUROSCIENCE

Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity

(2020) Michelle Corkrum et al.   NEURON

Microglia mediate forgetting via complement-dependent synaptic elimination

(2020) Chao Wang et al.   SCIENCE

Structural basis of astrocytic Ca2+ signals at tripartite synapses

(2020) Misa Arizono et al.   Nature Communications

Astroglia-specific contributions to the regulation of synapses, cognition and behaviour

(2020) Marcus Augusto-Oliveira et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Neuroinflammatory inhibition of synaptic long‐term potentiation requires immunometabolic reprogramming of microglia

(2020) Elisa M. York et al.   GLIA

Astrocytes Control Sensory Acuity via Tonic Inhibition in the Thalamus

(2020) Hankyul Kwak et al.   NEURON

LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia

(2020) Christian Henneberger et al.   NEURON

Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development

(2020) Rafael Falcón-Moya et al.   Nature Communications

Light microscopy based approach for mapping connectivity with molecular specificity

(2020) Fred Y. Shen et al.   Nature Communications

Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits

(2020) Najate Benamer et al.   Nature Communications

Activation of astrocytes in hippocampus decreases fear memory through adenosine A1 receptors

(2020) Yulan Li et al.   eLife

Glia-selective deletion of complement C1q prevents radiation-induced cognitive deficits and neuroinflammation

(2020) Mineh Markarian et al.   CANCER RESEARCH

Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis

(2020) Joon-Hyuk Lee et al.   NATURE

Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age

(2019) Sonia Olivia Spitzer et al.   NEURON

Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer’s disease

(2019) Jong-Hyun Park et al.   Science Advances

Region- and cell type-specific facilitation of synaptic function at destination synapses induced by oligodendrocyte depolarization

(2019) Yoshihiko Yamazaki et al.   JOURNAL OF NEUROSCIENCE

Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue

(2019) Jun Nagai et al.   CELL

Glutamate versus GABA in neuron–oligodendroglia communication

(2019) Chloé Habermacher et al.   GLIA

Diversity in the oligodendrocyte lineage: Plasticity or heterogeneity?

(2019) Sarah Foerster et al.   GLIA

Glutamate-Releasing SWELL1 Channel in Astrocytes Modulates Synaptic Transmission and Promotes Brain Damage in Stroke

(2019) Junhua Yang et al.   NEURON

Oligodendrocytes regulate presynaptic properties and neurotransmission through BDNF signaling in the mouse brainstem

(2019) Miae Jang et al.   eLife

The Emerging Nature of Astrocyte Diversity

(2019) Baljit S. Khakh et al.   Annual Review of Neuroscience

Neuron-Glia Signaling in Synapse Elimination

(2019) Daniel K. Wilton et al.   Annual Review of Neuroscience

Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling

(2019) Georgia Gunner et al.   NATURE NEUROSCIENCE

Microglia-Triggered Plasticity of Intrinsic Excitability Modulates Psychomotor Behaviors in Acute Cerebellar Inflammation

(2019) Masamichi Yamamoto et al.   Cell Reports

Microglia Biology: One Century of Evolving Concepts

(2019) Marco Prinz et al.   CELL

Epigenetic regulation of microglial phosphatidylinositol 3‐kinase pathway involved in long‐term potentiation and synaptic plasticity in rats

(2019) Genevieve Saw et al.   GLIA

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

(2018) Fabia Filipello et al.   IMMUNITY

Gliotransmission: Beyond Black-and-White

(2018) Iaroslav Savtchouk et al.   JOURNAL OF NEUROSCIENCE

Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

(2018) Yubin Huang et al.   NATURE NEUROSCIENCE

Control of motor coordination by astrocytic tonic GABA release through modulation of excitation/inhibition balance in cerebellum

(2018) Junsung Woo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal activity determines distinct gliotransmitter release from a single astrocyte

(2018) Ana Covelo et al.   eLife

Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau

(2018) Silvia S. Kang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cholecystokinin switches the plasticity of GABA synapses in the dorsomedial hypothalamus via astrocytic ATP release

(2018) Karen M Crosby et al.   JOURNAL OF NEUROSCIENCE

Reducing Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior

(2018) Xinzhu Yu et al.   NEURON

Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors

(2018) Elena Blanco-Suarez et al.   NEURON

Glia as architects of central nervous system formation and function

(2018) Nicola J. Allen et al.   SCIENCE

Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells

(2018) Marco Matos et al.   Nature Communications

Recognition and Treatment of Cognitive Dysfunction in Major Depressive Disorder

(2018) Hannah Zuckerman et al.   Frontiers in Psychiatry

Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease

(2017) Angela Gomez-Arboledas et al.   GLIA

Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury

(2017) Enmanuel J. Perez et al.   JOURNAL OF CLINICAL INVESTIGATION

Microglia-derived IL-1β contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats

(2017) Qianpeng Han et al.   Journal of Neuroinflammation

Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain

(2017) Maria I. Fonseca et al.   Journal of Neuroinflammation

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways

(2017) Yvonne Schwarz et al.   NATURE NEUROSCIENCE

Cell Biology of Astrocyte-Synapse Interactions

(2017) Nicola J. Allen et al.   NEURON

Astroglial Versus Neuronal D-Serine: Check Your Controls!

(2017) Herman Wolosker et al.   TRENDS IN NEUROSCIENCES

Astroglial versus Neuronal D-Serine: Fact Checking

(2017) Thomas Papouin et al.   TRENDS IN NEUROSCIENCES

TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice

(2017) Maria Cristina Marrone et al.   Nature Communications

The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting

(2016) Christopher S. von Bartheld et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Sphingosine-1-Phosphate (S1P) Impacts Presynaptic Functions by Regulating Synapsin I Localization in the Presynaptic Compartment

(2016) L. Riganti et al.   JOURNAL OF NEUROSCIENCE

TNF-α Differentially Regulates Synaptic Plasticity in the Hippocampus and Spinal Cord by Microglia-Dependent Mechanisms after Peripheral Nerve Injury

(2016) Yong Liu et al.   JOURNAL OF NEUROSCIENCE

Deficient autophagy in microglia impairs synaptic pruning and causes social behavioral defects

(2016) H-J Kim et al.   MOLECULAR PSYCHIATRY

Integrins in synapse regulation

(2016) Yun Kyung Park et al.   NATURE REVIEWS NEUROSCIENCE

Extracellular vesicles round off communication in the nervous system

(2016) Vivian Budnik et al.   NATURE REVIEWS NEUROSCIENCE

Microglial TNF-α Suppresses Cocaine-Induced Plasticity and Behavioral Sensitization

(2016) Gil M. Lewitus et al.   NEURON

IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline

(2016) Amy K. Y. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

(2016) S. Marques et al.   SCIENCE

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

The Rise and Fall of the d -Serine-Mediated Gliotransmission Hypothesis

(2016) Herman Wolosker et al.   TRENDS IN NEUROSCIENCES

Astrocytes gate Hebbian synaptic plasticity in the striatum

(2016) Silvana Valtcheva et al.   Nature Communications

Astrocytic GABA transporter activity modulates excitatory neurotransmission

(2016) Kim Boddum et al.   Nature Communications

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Active endocannabinoids are secreted on extracellular membrane vesicles

(2015) M. Gabrielli et al.   EMBO REPORTS

NG2-glia and their functions in the central nervous system

(2015) L. Dimou et al.   GLIA

Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes

(2015) Sébastien Sultan et al.   NEURON

Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2

(2015) Fikri Birey et al.   NEURON

Neuroglial Transmission

(2015) Vidar Gundersen et al.   PHYSIOLOGICAL REVIEWS

Brain extracellular matrix retains connectivity in neuronal networks

(2015) Arthur Bikbaev et al.   Scientific Reports

Microglia Development and Function

(2014) Debasis Nayak et al.   Annual Review of Immunology

d-Serine and Serine Racemase are Localized to Neurons in the Adult Mouse and Human Forebrain

(2014) Darrick T. Balu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Activity-Dependent Structural Plasticity of Perisynaptic Astrocytic Domains Promotes Excitatory Synapse Stability

(2014) Yann Bernardinelli et al.   CURRENT BIOLOGY

The glia/neuron ratio: How it varies uniformly across brain structures and species and what that means for brain physiology and evolution

(2014) Suzana Herculano-Houzel   GLIA

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

(2014) Seonmi Jo et al.   NATURE MEDICINE

Activity-dependent regulation of astrocyte GAT levels during synaptogenesis

(2014) Allie K Muthukumar et al.   NATURE NEUROSCIENCE

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

(2014) Yang Zhan et al.   NATURE NEUROSCIENCE

Microglial phagocytosis of live neurons

(2014) Guy C. Brown et al.   NATURE REVIEWS NEUROSCIENCE

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Astrocytes revisited: concise historic outlook on glutamate homeostasis and signaling

(2013) Vladimir Parpura et al.   CROATIAN MEDICAL JOURNAL

D-Serine in Glia and Neurons Derives from 3-Phosphoglycerate Dehydrogenase

(2013) J. T. Ehmsen et al.   JOURNAL OF NEUROSCIENCE

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

(2013) Won-Suk Chung et al.   NATURE

TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement

(2013) Allison R Bialas et al.   NATURE NEUROSCIENCE

Microglia: Multiple roles in surveillance, circuit shaping, and response to injury

(2013) E. E. Benarroch   NEUROLOGY

Cell adhesion and homeostatic synaptic plasticity

(2013) Agnes Thalhammer et al.   NEUROPHARMACOLOGY

Microglia Actively Regulate the Number of Functional Synapses

(2013) Kyungmin Ji et al.   PLoS One

Cell Selective Conditional Null Mutations of Serine Racemase Demonstrate a Predominate Localization in Cortical Glutamatergic Neurons

(2012) Michael A. Benneyworth et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism

(2012) Flavia Antonucci et al.   EMBO JOURNAL

Heterosynaptic long-term depression mediated by ATP released from astrocytes

(2012) Jiadong Chen et al.   GLIA

Artifact versus reality-How astrocytes contribute to synaptic events

(2012) Maiken Nedergaard et al.   GLIA

Astrocyte-Originated ATP Protects A 1-42-Induced Impairment of Synaptic Plasticity

(2012) E. S. Jung et al.   JOURNAL OF NEUROSCIENCE

Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors

(2012) Nicola J. Allen et al.   NATURE

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Genetically Encoded Calcium Indicators and Astrocyte Calcium Microdomains

(2012) Xiaoping Tong et al.   NEUROSCIENTIST

BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus

(2012) F. D. Jeanneteau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunogold Detection of L-glutamate and D-serine in Small Synaptic-Like Microvesicles in Adult Hippocampal Astrocytes

(2011) L.H. Bergersen et al.   CEREBRAL CORTEX

Molecular signals of plasticity at the tetrapartite synapse

(2011) Alexander Dityatev et al.   CURRENT OPINION IN NEUROBIOLOGY

Synapses between NG2 glia and neurons

(2011) Dominik Sakry et al.   JOURNAL OF ANATOMY

The Relative Roles of Diffusion and Uptake in Clearing Synaptically Released Glutamate Change during Early Postnatal Development

(2011) C. G. Thomas et al.   JOURNAL OF NEUROSCIENCE

CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity

(2011) J. T. Rogers et al.   JOURNAL OF NEUROSCIENCE

Astrocyte Calcium Signaling Transforms Cholinergic Modulation to Cortical Plasticity In Vivo

(2011) N. Takata et al.   JOURNAL OF NEUROSCIENCE

Contribution of astrocytic glutamate and GABA uptake to corticostriatal information processing

(2011) Valérie Goubard et al.   JOURNAL OF PHYSIOLOGY-LONDON

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

(2011) Eiji Shigetomi et al.   NATURE NEUROSCIENCE

NG2-glia as Multipotent Neural Stem Cells: Fact or Fantasy?

(2011) William D. Richardson et al.   NEURON

Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC

(2011) Hakan Kucukdereli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fear Erasure in Mice Requires Synergy Between Antidepressant Drugs and Extinction Training

(2011) N. N. Karpova et al.   SCIENCE

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Postnatal Switch from Synaptic to Extrasynaptic Transmission between Interneurons and NG2 Cells

(2010) M. Velez-Fort et al.   JOURNAL OF NEUROSCIENCE

Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke

(2010) Andrew N. Clarkson et al.   NATURE

Long-term potentiation depends on release of d-serine from astrocytes

(2010) Christian Henneberger et al.   NATURE

Enhanced synaptic connectivity and epilepsy in C1q knockout mice

(2010) Yunxiang Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Channel-Mediated Tonic GABA Release from Glia

(2010) S. Lee et al.   SCIENCE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

Axons and astrocytes release ATP and glutamate to evoke calcium signals in NG2-glia

(2009) Nicola Hamilton et al.   GLIA

The principal neurons of the medial nucleus of the trapezoid body and NG2+glial cells receive coordinated excitatory synaptic input

(2009) Jochen Müller et al.   JOURNAL OF GENERAL PHYSIOLOGY

Astrocyte secreted proteins selectively increase hippocampal GABAergic axon length, branching, and synaptogenesis

(2009) Ethan G. Hughes et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Astrocyte-Mediated Distributed Plasticity at Hypothalamic Glutamate Synapses

(2009) Grant R.J. Gordon et al.   NEURON

NG2-expressing cells in the nervous system revealed by the NG2-EYFP-knockin mouse

(2008) Khalad Karram et al.   GENESIS

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Spiking and nonspiking classes of oligodendrocyte precursor glia in CNS white matter

(2008) Ragnhildur Káradóttir et al.   NATURE NEUROSCIENCE