Review
Dermatology
Claudio Conforti, Roberta Giuffrida, Sara Fadda, Annatonia Fai, Paolo Romita, Iris Zalaudek, Caterina Dianzani
Summary: This review highlights the importance of choosing the most suitable topical dermocosmetics for different skin types, along with the effective timing and method of combining them with standard acne treatment. Although there is a lack of clinical studies on cleansers, the daily use of moisturizers, cleansers, and sunscreens can help reduce both inflammatory and non-inflammatory acne lesions.
DERMATOLOGIC THERAPY
(2021)
Review
Dermatology
Ichiro Kurokawa, Miwa Kobayashi, Yuko Nomura, Masatoshi Abe, Delphine Kerob, Brigitte Dreno
Summary: In Japan and other countries, acne vulgaris is a common disease and a frequent reason for consultation with dermatologists. Dermocosmetics, which contain dermatologically active ingredients, play a role in managing acne either as monotherapy or in combination with prescription therapy. These products target specific aspects of acne pathophysiology and also have beneficial effects on skin barrier function. Additionally, dermocosmetics may positively impact the skin microbiome.
DERMATOLOGY AND THERAPY
(2023)
Review
Dermatology
Elena Araviiskaia, Jose Luis Lopez Estebaranz, Carlo Pincelli
Summary: Dermocosmetics are increasingly recognized as an important adjunct in acne management, helping to minimize side effects of medications, improve efficacy of treatments, and limit exposure to environmental factors. Active ingredients in dermocosmetics for acne, such as sebum-controlling and anti-inflammatory agents, can modulate the pathogenic pathways in acne, leading to improved clinical signs and reduced side effects of pharmacological treatments. Overall, dermocosmetics have shown to be beneficial in clinical practice, improving patient satisfaction and treatment adherence.
JOURNAL OF DERMATOLOGICAL TREATMENT
(2021)
Article
Medicine, General & Internal
Ewelina Firlej, Wioleta Kowalska, Karolina Szymaszek, Jacek Rolinski, Joanna Bartosinska
Summary: Acne vulgaris is a common skin disease caused by multiple factors and inflammation. Recent studies have found that skin immune cells play a significant role in the course of the disease.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Dermatology
Melissa A. Nickles, Eden Lake
Summary: Dapsone gel shows promise in treating acne, with a success rate of 40.1-69.4% for monotherapy and a greater reduction in inflammatory lesions compared to noninflammatory lesions. Treatments combining dapsone gel with other acne medications were also studied, showing mild adverse effects and promising results.
INTERNATIONAL JOURNAL OF DERMATOLOGY
(2022)
Article
Dermatology
Dong Hyo Kim, Ji Hoon Yang, Soo Ick Cho, Ji Young Yoon, Ji Won Kim, Sungjun Choi, Dae Hun Suh
Summary: The clinical efficacy of epidermal growth factor ointment (EGFO) on acne and acne scars was evaluated in this study. The results indicated that EGFO significantly improved acne lesions and scars. Treatment with EGFO altered the expression of various factors related to acne and scarring.
Article
Health Care Sciences & Services
Karolina Chilicka, Aleksandra M. Rogowska, Renata Szygula
Summary: This study examined the effectiveness of hydrogen purification treatment for women with acne vulgaris, showing that the treatment significantly improved skin parameters, reduced sebum levels, and increased skin moisture. Therefore, topical hydrogen purification is an effective and safe treatment for acne vulgaris.
Article
Microbiology
Giovanna Mosaico, Giulia Artuso, Mara Pinna, Gloria Denotti, Germano Orru, Cinzia Casu
Summary: This study aims to investigate the effect of L. reuteri on facial skin in orthodontic patients. Two case reports showed that the use of L. reuteri as a probiotic during fixed orthodontic treatment significantly improved gum hypertrophy and acne vulgaris.
Review
Pharmacology & Pharmacy
Parisa Ghasemiyeh, Soliman Mohammadi-Samani, Kiarash Noorizadeh, Ouriel Zadmehr, Shiva Rasekh, Shiva Mohammadi-Samani, Dorsa Dehghan
Summary: Acne vulgaris is a chronic inflammatory skin disorder that requires early management due to its harmful consequences. The severity of acne determines the suitable pharmacotherapy regimens. Topical treatment options are preferred for patients with mild to moderate acne due to their lower adverse reactions. Nanotechnology and novel drug delivery systems can enhance skin penetration and targeted delivery.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Giorgia Condro, Marta Guerini, Michela Castello, Paola Perugini
Summary: The skin microbiota plays an important role in maintaining healthy skin, but its balance can be disrupted by various factors, leading to the development of skin diseases. The correlation between diseases like acne vulgaris, atopic dermatitis, rosacea and the skin microbiota is still unclear, and more research is needed to explore the specific subspecies and strains involved.
Review
Pharmacology & Pharmacy
Christopher R. Piszczatoski, Jason Powell
Summary: This article reviews the clinical data of topical clascoterone for the treatment of acne vulgaris, showing that it may be an effective and safe option with similar efficacy rates to current medications through a novel mechanism of action.
CLINICAL THERAPEUTICS
(2021)
Review
Infectious Diseases
Ana M. Martins, Joana M. Marto, Jodi L. Johnson, Emmy M. Graber
Summary: Minocycline, a semisynthetic tetracycline-derived antibiotic, shows promise in treating dermatological disorders like acne with its anti-inflammatory properties. However, systemic administration of minocycline may lead to more serious adverse effects compared to other tetracyclines.
Article
Dermatology
Parvathy Santhosh, Mamatha George
Summary: Clascoterone is a topical drug approved by the FDA for the treatment of acne vulgaris, with a mechanism of action involving androgen receptor inhibition. It shows promising results in reducing acne symptoms with mild and infrequent adverse effects, and long-term safety studies have not shown systemic antiandrogenic effects in male participants.
INTERNATIONAL JOURNAL OF DERMATOLOGY
(2021)
Article
Dermatology
Yong-Deok Lee, Jin-Kyoung Yang, Sunmi Han, Bo Ri Kim, Jung-Won Shin, Joona Bang, Sehoon Kim
Summary: Acne vulgaris, a common skin disease, can be effectively treated by topical photodynamic therapy (PDT) using a new biocompatible nanoformulation, MBSD, which shows antimicrobial activity against Cutibacterium acnes and reduces acne lesions and sebum production. The PDT procedure is painless and safe.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Medicine, General & Internal
Yvonne Nong, Nimrit Gahoonia, Julianne Rizzo, Waqas Burney, Raja K. Sivamani, Jessica Maloh
Summary: In this 8-week open-label study, a botanical skin care regimen was found to be well-tolerated and effective in reducing facial and truncal acne lesion counts, increasing skin hydration, reducing sebum production, and improving positive effects and moods in individuals with mild to moderate acne.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Dermatology
B. Dreno, E. Araviiskaia, E. Berardesca, G. Gontijo, M. Sanchez Viera, L. F. Xiang, R. Martin, T. Bieber
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2016)
Review
Dermatology
H. P. Gollnick, V. Bettoli, J. Lambert, E. Araviiskaia, I. Binic, C. Dessinioti, I. Galadari, R. Ganceviciene, N. Ilter, M. Kaegi, L. Kemeny, J. L. Lopez-Estebaranz, A. Massa, C. Oprica, W. Sinclair, J. C. Szepietowski, B. Dreno
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2016)
Article
Dermatology
J. Tan, H. Schoefer, E. Araviiskaia, F. Audibert, N. Kerrouche, M. Berg
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2016)
Article
Dermatology
Diane M. Thiboutot, Brigitte Dreno, Abdullah Abanmi, Andrew F. Alexis, Elena Araviiskaia, Maria Isabel Barona Cabal, Vincenzo Bettoli, Flordeliz Casintahan, Steven Chow, Adilson da Costa, Tam El Ouazzani, Chee-Leok Goh, Harald P. M. Gollnick, Minerva Gomez, Nobukazu Hayashi, Maria Isabel Herane, Juan Honeyman, Sewon Kang, Lajos Kemeny, Raj Kubba, Julien Lambert, Alison M. Layton, James J. Leyden, Jose Luis Lopez-Estebaranz, Nopadon Noppakun, Falk Ochsendorf, Cristina Oprica, Beatriz Orozco, Montserrat Perez, Jaime Piquero-Martin, Jo-Ann See, Dae Hun Suh, Jerry Tan, Vicente Torres Lozada, Patricia Troielli, Leihong Flora Xiang
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2018)
Article
Dermatology
B. Dreno, V. Bettoli, E. Araviiskaia, M. Sanchez Viera, A. Bouloc
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2018)
Review
Dermatology
B. Dreno, E. Araviiskaia, E. Berardesca, T. Bieber, J. Hawk, M. Sanchez-Viera, P. Wolkenstein
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2014)
Review
Dermatology
E. Araviiskaia, E. Berardesca, T. Bieber, G. Gontijo, M. Sanchez Viera, L. Marrot, B. Chuberre, B. Dreno
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2019)
Review
Dermatology
Elena Araviiskaia, Jose Luis Lopez Estebaranz, Carlo Pincelli
Summary: Dermocosmetics are increasingly recognized as an important adjunct in acne management, helping to minimize side effects of medications, improve efficacy of treatments, and limit exposure to environmental factors. Active ingredients in dermocosmetics for acne, such as sebum-controlling and anti-inflammatory agents, can modulate the pathogenic pathways in acne, leading to improved clinical signs and reduced side effects of pharmacological treatments. Overall, dermocosmetics have shown to be beneficial in clinical practice, improving patient satisfaction and treatment adherence.
JOURNAL OF DERMATOLOGICAL TREATMENT
(2021)
Review
Dermatology
B. Chuberre, E. Araviiskaia, T. Bieber, A. Barbaud
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2019)
Article
Dermatology
Jerry Tan, Julieta Spada, Cecilia Orlandi, Martina Kerscher, Maryna Anfilova, Sonya Abdulla, Adriana Florianova, Klaudia Preisz, Anita Altmayer, Catherine Delva, Delphine Kerob, Maiia Goldobina, Monika Arenbergerova, Svyatoslav Tuz, Elena Araviiskaia
JOURNAL OF COSMETIC DERMATOLOGY
(2020)
Article
Dermatology
Lesia Kirsanova, Elena Araviiskaia, Margarita Rybakova, Evgeny Sokolovsky, Alexey Bogantenkov, Firas Al-Niaimi
DERMATOLOGIC THERAPY
(2020)
Review
Dermatology
Brigitte Dreno, Elena Araviiskaia, Delphine Kerob, Anneke Andriessen, Maryna Anfilova, Monika Arenbergerova, Olga L. Forero Barrios, Zrinka Bukvic Mokos, Merete Haedersdal, Maja A. Hofmann, Ziad Khamaysi, Marita Kosmadaki, Aleksandra Lesiak, Elia Roo, Anca Zbranca-Toporas, Marni C. Wiseman, Sameer Zimmo, Lucie Guerin, Gabriella Fabbrocini
JOURNAL OF COSMETIC DERMATOLOGY
(2020)
Article
Dermatology
Firas Al-Niaimi, Ekaterina Glagoleva, Elena Araviiskaia
DERMATOLOGIC THERAPY
(2020)
Review
Dermatology
Elena Araviiskaia, Carlo Pincelli, Adele Sparavigna, Thomas Luger
Summary: Emollients are the mainstay treatment for atopic dermatitis. A new generation of emollients, called "emollients plus", contains active non-medicated substances and has both emollient and topical drug effects. The composition and modes of action of emollients plus can vary greatly, which may significantly affect their clinical efficacy. Studies have shown that emollients plus can restore and maintain skin barrier function at multiple levels.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
(2022)