Assessing the robustness of COVID-19 vaccine efficacy trials: systematic review and meta-analysis, January 2023
出版年份 2023 全文链接
标题
Assessing the robustness of COVID-19 vaccine efficacy trials: systematic review and meta-analysis, January 2023
作者
关键词
-
出版物
Eurosurveillance
Volume 28, Issue 22, Pages -
出版商
European Centre for Disease Control and Prevention (ECDC)
发表日期
2023-06-03
DOI
10.2807/1560-7917.es.2023.28.22.2200706
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial
- (2022) Lulu Bravo et al. LANCET
- Initial analysis of viral dynamics and circulating viral variants during the mRNA-1273 Phase 3 COVE trial
- (2022) Rolando Pajon et al. NATURE MEDICINE
- Final Analysis of Efficacy and Safety of Single-Dose Ad26.COV2.S
- (2022) Jerald Sadoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy, safety, and immunogenicity of the DNA SARS-CoV-2 vaccine (ZyCoV-D): the interim efficacy results of a phase 3, randomised, double-blind, placebo-controlled study in India
- (2022) Akash Khobragade et al. LANCET
- Impact of previous exposure to SARS-CoV-2 and of S-Trimer (SCB-2019) COVID-19 vaccination on the risk of reinfection: a randomised, double-blinded, placebo-controlled, phase 2 and 3 trial
- (2022) Igor Smolenov et al. LANCET INFECTIOUS DISEASES
- Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine
- (2022) Karen J. Hager et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and Safety of the RBD-Dimer–Based Covid-19 Vaccine ZF2001 in Adults
- (2022) Lianpan Dai et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of a Third Dose of BNT162b2 Covid-19 Vaccine
- (2022) Edson D. Moreira et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and Effectiveness of SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis
- (2022) Ramy Mohamed Ghazy et al. Vaccines
- The Fragility of Statistically Significant Results in Randomized Clinical Trials for COVID-19
- (2022) Takahiro Itaya et al. JAMA Network Open
- Thresholds for interpreting the fragility index derived from sample of randomised controlled trials in cardiology: a meta-epidemiologic study
- (2022) Mohammad Hassan Murad et al. BMJ Evidence-Based Medicine
- Efficacy of heterologous boosting against SARS-CoV-2 using a recombinant interferon-armed fusion protein vaccine (V-01): a randomized, double-blind and placebo-controlled phase III trial
- (2022) Xuan-Yi Wang et al. Emerging Microbes & Infections
- An exploratory analysis of the response to ChAdOx1 nCoV-19 (AZD1222) vaccine in males and females
- (2022) Natalie Gabrielle Marchevsky et al. EBioMedicine
- Safety and Efficacy of the NVX-CoV2373 COVID-19 Vaccine at Completion of the Placebo-Controlled Phase of a Randomized Controlled Trial
- (2022) Paul T Heath et al. CLINICAL INFECTIOUS DISEASES
- Evaluating the efficacy and safety of SpikoGen®, an Advax-CpG55.2–adjuvanted severe acute respiratory syndrome coronavirus 2 spike protein vaccine: a phase 3 randomized placebo-controlled trial
- (2022) Payam Tabarsi et al. CLINICAL MICROBIOLOGY AND INFECTION
- Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial
- (2022) Karin Hardt et al. LANCET INFECTIOUS DISEASES
- Efficacy, Immunogenicity, and Safety of the Two-Dose Schedules of TURKOVAC versus CoronaVac in Healthy Subjects: A Randomized, Observer-Blinded, Non-Inferiority Phase III Trial
- (2022) Mine Durusu Tanriover et al. Vaccines
- Meta-analyses in paediatric surgery are often fragile: implications and consequences
- (2021) Arne Schröder et al. PEDIATRIC SURGERY INTERNATIONAL
- The Statistical Fragility of Platelet-Rich Plasma in Rotator Cuff Surgery: A Systematic Review and Meta-analysis
- (2021) Robert L. Parisien et al. AMERICAN JOURNAL OF SPORTS MEDICINE
- The Fragility Index of Hip Arthroscopy Randomized Controlled Trials: A Systematic Survey
- (2021) David R. Maldonado et al. ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
- Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials
- (2021) Merryn Voysey et al. LANCET
- Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia
- (2021) Denis Y Logunov et al. LANCET
- Fragility of results from randomized controlled trials supporting the guidelines for the treatment of osteoporosis: a retrospective analysis
- (2021) X. Huang et al. OSTEOPOROSIS INTERNATIONAL
- Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial
- (2021) Katherine R W Emary et al. LANCET
- Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
- (2021) Nina H. Schultz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant
- (2021) Shabir A. Madhi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19
- (2021) Jerald Sadoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant
- (2021) Vivek Shinde et al. NEW ENGLAND JOURNAL OF MEDICINE
- PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews
- (2021) Matthew J Page et al. BMJ-British Medical Journal
- The PRISMA 2020 statement: an updated guideline for reporting systematic reviews
- (2021) Matthew J Page et al. BMJ-British Medical Journal
- The Fragility of Statistical Significance in Cartilage Restoration of the Knee: A Systematic Review of Randomized Controlled Trials
- (2021) Robert L. Parisien et al. Cartilage
- Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults
- (2021) Nawal Al Kaabi et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey
- (2021) Mine Durusu Tanriover et al. LANCET
- Safety, Immunogenicity, and Efficacy of the BNT162b2 Covid-19 Vaccine in Adolescents
- (2021) Robert W. Frenck et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine
- (2021) Paul T. Heath et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase
- (2021) Hana M. El Sahly et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine through 6 Months
- (2021) Stephen J. Thomas et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Phase III, Observer-blind, Randomized, Placebo-controlled Study of the Efficacy, Safety, and Immunogenicity of SARS-CoV-2 Inactivated Vaccine in Healthy Adults Aged 18–59 Years: An Interim Analysis in Indonesia
- (2021) Eddy Fadlyana et al. VACCINE
- Final efficacy analysis, interim safety analysis, and immunogenicity of a single dose of recombinant novel coronavirus vaccine (adenovirus type 5 vector) in adults 18 years and older: an international, multicentre, randomised, double-blinded, placebo-controlled phase 3 trial
- (2021) Scott A Halperin et al. LANCET
- Efficacy, safety, and lot-to-lot immunogenicity of an inactivated SARS-CoV-2 vaccine (BBV152): interim results of a randomised, double-blind, controlled, phase 3 trial
- (2021) Raches Ella et al. LANCET
- Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine
- (2021) Ann R. Falsey et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico
- (2021) Lisa M. Dunkle et al. NEW ENGLAND JOURNAL OF MEDICINE
- Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age
- (2021) Emmanuel B. Walter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Fragility indices for only sufficiently likely modifications
- (2021) Benjamin R. Baer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil
- (2021) Sue Ann Costa Clemens et al. Nature Communications
- Comparing the clinical efficacy of COVID-19 vaccines: a systematic review and network meta-analysis
- (2021) Victoria Rotshild et al. Scientific Reports
- Fragility Index and Fragility Quotient in Randomized Controlled Trials on Corticosteroids in ARDS Due to COVID-19 and Non-COVID-19 Etiology
- (2021) Maria Vargas et al. Journal of Clinical Medicine
- Efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate in ten countries in Europe and Latin America (HERALD): a randomised, observer-blinded, placebo-controlled, phase 2b/3 trial
- (2021) Peter G Kremsner et al. LANCET INFECTIOUS DISEASES
- Efficacy and safety of the BNT162b2 mRNA COVID-19 vaccine in participants with a history of cancer: subgroup analysis of a global phase 3 randomized clinical trial
- (2021) Stephen J. Thomas et al. VACCINE
- Evaluation of the fragility of pivotal trials used to support US Food and Drug Administration approval for plaque psoriasis
- (2020) Sophia Z. Shalhout et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Factors that impact fragility index and their visualizations
- (2020) Lifeng Lin JOURNAL OF EVALUATION IN CLINICAL PRACTICE
- Application of the Reverse Fragility Index to Statistically Nonsignificant Randomized Clinical Trial Results
- (2020) Muhammad Shahzeb Khan et al. JAMA Network Open
- The Fragility Index and Trial Significance
- (2020) Alexander Chaitoff et al. JAMA Internal Medicine
- Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
- (2020) Merryn Voysey et al. LANCET
- Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
- (2020) Lindsey R. Baden et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
- (2020) Fernando P. Polack et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Fragility Index—P Values Reimagined, Flaws and All
- (2019) Sergio A. Acuna et al. JAMA Surgery
- Over-reliance on p values in Urology: Fragility of findings in the hydronephrosis literature calls for systematic reporting of robustness indicators
- (2019) Mandy Rickard et al. UROLOGY
- The fragility index of practice changing clinical trials is low and highly correlated with P-values
- (2019) Joshua D. Niforatos et al. JOURNAL OF CLINICAL EPIDEMIOLOGY
- Fragility Index in Cardiovascular Randomized Controlled Trials
- (2019) Muhammad Shahzeb Khan et al.
- The Fragility Index in Randomized Clinical Trials as a Means of Optimizing Patient Care
- (2018) Christopher J. Tignanelli et al. JAMA Surgery
- The ASA's Statement onp-Values: Context, Process, and Purpose
- (2016) Ronald L. Wasserstein et al. AMERICAN STATISTICIAN
- Does Sample Size Matter When Interpreting the Fragility Index?
- (2016) Wael Ahmed et al. CRITICAL CARE MEDICINE
- Statistical tests, P values, confidence intervals, and power: a guide to misinterpretations
- (2016) Sander Greenland et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index
- (2014) Michael Walsh et al. JOURNAL OF CLINICAL EPIDEMIOLOGY
- Statistics in Brief: The Importance of Sample Size in the Planning and Interpretation of Medical Research
- (2008) David Jean Biau et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started