Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis

GPR35 promotes neutrophil recruitment in response to serotonin metabolite 5-HIAA

(2022) Marco De Giovanni et al.   CELL

Structure–Activity Relationship Studies of Coumarin-like Diacid Derivatives as Human G Protein-Coupled Receptor-35 (hGPR35) Agonists and a Consequent New Design Principle

(2021) Lai Wei et al.   JOURNAL OF MEDICINAL CHEMISTRY

Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment

(2021) Ester Pagano et al.   GUT

GPR35 in Intestinal Diseases: From Risk Gene to Function

(2021) Berna Kaya et al.   Frontiers in Immunology

Enhancing the Signaling of GPCRs via Orthosteric Ions

(2020) H. C. Stephen Chan et al.   ACS Central Science

Advances in therapeutic peptides targeting G protein-coupled receptors

(2020) Anthony P. Davenport et al.   NATURE REVIEWS DRUG DISCOVERY

Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1+ Macrophages Regulates Intestinal Homeostasis

(2020) Berna Kaya et al.   Cell Reports

Functional Metabolomics Reveal the Role of AHR/GPR35 Mediated Kynurenic acid Gradient Sensing in Chemotherapy-induced Intestinal Damage

(2020) Di Wang et al.   Acta Pharmaceutica Sinica B

Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation

(2018) Leandro Z. Agudelo et al.   Cell Metabolism

G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?

(2018) Krishna Sriram et al.   MOLECULAR PHARMACOLOGY

Disruption of GPR35 Exacerbates Dextran Sulfate Sodium-Induced Colitis in Mice

(2018) Shukkur M. Farooq et al.   DIGESTIVE DISEASES AND SCIENCES

COX-2–PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis

(2018) Yuan Li et al.   EBioMedicine

G protein-coupled receptor 35 contributes to mucosal repair in mice via migration of colonic epithelial cells

(2017) Takuya Tsukahara et al.   PHARMACOLOGICAL RESEARCH

Evaluation of chemical mediators and cellular response during acute and chronic gut inflammatory response induced by dextran sodium sulfate in mice

(2012) Allisson Freire Bento et al.   BIOCHEMICAL PHARMACOLOGY

Genome-wide association analysis in Primary sclerosing cholangitis and ulcerative colitis identifies risk loci atGPR35andTCF4

(2012) David Ellinghaus et al.   HEPATOLOGY

Mesalamine in the treatment and maintenance of remission of ulcerative colitis

(2012) Maggie Ham et al.   Expert Review of Clinical Pharmacology

Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα13 and β-arrestin-2

(2010) Laura Jenkins et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and  -Arrestin2 with Antinociceptive Activity

(2010) P. Zhao et al.   MOLECULAR PHARMACOLOGY

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY