GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis

Oncogene-regulated release of extracellular vesicles

(2021) Seda Kilinc et al.   DEVELOPMENTAL CELL

ALIX- and ESCRT-III–dependent sorting of tetraspanins to exosomes

(2020) Jorge Larios et al.   JOURNAL OF CELL BIOLOGY

Glutamine deprivation alters the origin and function of cancer cell exosomes

(2020) Shih‐Jung Fan et al.   EMBO JOURNAL

An Interferon-Driven Oxysterol-Based Defense against Tumor-Derived Extracellular Vesicles

(2019) Angelica Ortiz et al.   CANCER CELL

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

Exosome-Mediated Metastasis: Communication from a Distance

(2019) Inbal Wortzel et al.   DEVELOPMENTAL CELL

Tetraspanin blockage reduces exosome-mediated HIV-1 entry

(2018) Brian Sims et al.   ARCHIVES OF VIROLOGY

Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation

(2018) Eva Maria Wenzel et al.   Nature Communications

The interplay between exosomes and autophagy – partners in crime

(2018) Jing Xu et al.   JOURNAL OF CELL SCIENCE

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

(2018) Gang Chen et al.   NATURE

Clinical Significance of Extracellular Vesicles in Plasma from Glioblastoma Patients

(2018) Daniela Osti et al.   CLINICAL CANCER RESEARCH

Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23

(2017) Yao Wei et al.   Nature Communications

QuPath: Open source software for digital pathology image analysis

(2017) Peter Bankhead et al.   Scientific Reports

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

Non-coding RNA profiling of the developing murine lens

(2016) Shahid Y. Khan et al.   EXPERIMENTAL EYE RESEARCH

Malignant messengers

(2016) J. Kaiser   SCIENCE

KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

(2016) Andrew J. McKenzie et al.   Cell Reports

Expression of ocular albinism 1 (OA1), 3, 4- dihydroxy- L-phenylalanine (DOPA) receptor, in both neuronal and non-neuronal organs

(2015) Nobuhiko Fukuda et al.   BRAIN RESEARCH

Heparanase activates the syndecan-syntenin-ALIX exosome pathway

(2015) Bart Roucourt et al.   CELL RESEARCH

Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct

(2015) Rong Xu et al.   METHODS

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway

(2015) Alejandra Tomas et al.   Nature Communications

Directional cell movement through tissues is controlled by exosome secretion

(2015) Bong Hwan Sung et al.   Nature Communications

The coordinated action of the MVB pathway and autophagy ensures cell survival during starvation

(2015) Martin Müller et al.   eLife

KRAS-dependent sorting of miRNA to exosomes

(2015) Diana J Cha et al.   eLife

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2

(2014) Rania Ghossoub et al.   Nature Communications

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Melanosomal Dynamics Assessed with a Live-Cell Fluorescent Melanosomal Marker

(2012) Jan M. Bruder et al.   PLoS One

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis

(2011) Guillaume van Niel et al.   DEVELOPMENTAL CELL

The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) function

(2011) F. Giordano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling pathways in melanosome biogenesis and pathology

(2010) Maria Vittoria Schiaffino   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

(2010) Chieh Hsu et al.   JOURNAL OF CELL BIOLOGY

Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes

(2010) Jung Eun Park et al.   MOLECULAR & CELLULAR PROTEOMICS

SRC-3Δ4 Mediates the Interaction of EGFR with FAK to Promote Cell Migration

(2010) Weiwen Long et al.   MOLECULAR CELL

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE