Evidence in support of the bone marrow as the primary lesion in axial spondyloarthritis

Characterization of Blood Mucosal Associated Invariant T ( MAIT ) cells in Axial Spondyloarthritis and of resident MAITs from control axial enthesis

(2022) Nicolas Rosine et al.   Arthritis & Rheumatology

IL-17A and TNF Modulate Normal Human Spinal Entheseal Bone and Soft Tissue Mesenchymal Stem Cell Osteogenesis, Adipogenesis, and Stromal Function

(2021) Tobias Russell et al.   Cells

TNF-α-mediated m6A modification of ELMO1 triggers directional migration of mesenchymal stem cell in ankylosing spondylitis

(2021) Zhongyu Xie et al.   Nature Communications

Integrative analysis of long non-coding RNA and messenger RNA expression in toll-like receptor 4-primed mesenchymal stem cells of ankylosing spondylitis

(2021) Yu-Xi Li et al.   Annals of Translational Medicine

GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis

(2020) Daniel Regan-Komito et al.   Nature Communications

GM-CSF Primes Proinflammatory Monocyte Responses in Ankylosing Spondylitis

(2020) Hui Shi et al.   Frontiers in Immunology

IL‐17A expressed on neutrophil extracellular traps promotes mesenchymal stem cell differentiation toward bone‐forming cells in ankylosing spondylitis

(2020) Charalampos Papagoras et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

SNP-adjacent super enhancer network mediates enhanced osteogenic differentiation of MSCs in ankylosing spondylitis

(2020) Wenhui Yu et al.   HUMAN MOLECULAR GENETICS

Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation

(2019) Triantafyllos Chavakis et al.   NATURE IMMUNOLOGY

IL-17A Inhibition Diminishes Inflammation and New Bone Formation In Experimental Spondyloarthritis

(2018) Melissa N. van Tok et al.   Arthritis & Rheumatology

Type 3 innate lymphoid cells producing IL-17 and IL-22 are expanded in the gut, in the peripheral blood, synovial fluid and bone marrow of patients with ankylosing spondylitis

(2015) Francesco Ciccia et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells

(2012) Jonathan P Sherlock et al.   NATURE MEDICINE

Analysis of IL-17+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response

(2011) Heiner Appel et al.   ARTHRITIS RESEARCH & THERAPY