The antifungal effect induced by itraconazole in Candida parapsilosis largely depends on the oxidative stress generated at the mitochondria

Lack of Functional Trehalase Activity in Candida parapsilosis Increases Susceptibility to Itraconazole

(2022) Ruth Sánchez-Fresneda et al.   Journal of Fungi

A Candida parapsilosis Overexpression Collection Reveals Genes Required for Pathogenesis

(2021) Sára E. Pál et al.   Journal of Fungi

Interesting antifungal drug targets in the central metabolism of Candida albicans

(2021) Stefanie Wijnants et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Sugar Phosphorylation Controls Carbon Source Utilization and Virulence of Candida albicans

(2020) Stefanie Wijnants et al.   Frontiers in Microbiology

Candida parapsilosis: from Genes to the Bedside

(2019) Renáta Tóth et al.   CLINICAL MICROBIOLOGY REVIEWS

The MAPK Hog1 mediates the response to amphotericin B in Candida albicans

(2019) José Pedro Guirao-Abad et al.   FUNGAL GENETICS AND BIOLOGY

Cooperative Role of MAPK Pathways in the Interaction of Candida albicans with the Host Epithelium

(2019) Inês Correia et al.   Microorganisms

Micafungin Enhances the Human Macrophage Response to Candida albicans through β-Glucan Exposure

(2018) José Pedro Guirao-Abad et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Central Role of the Trehalose Biosynthesis Pathway in the Pathogenesis of Human Fungal Infections: Opportunities and Challenges for Therapeutic Development

(2017) Arsa Thammahong et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Trehalose pathway as an antifungal target

(2016) John R. Perfect et al.   Virulence

Trehalose as antifungal target: The picture is still incomplete

(2016) Juan-Carlos Argüelles   Virulence

Development of fluconazole resistance in a series of Candida parapsilosis isolates from a persistent candidemia patient with prolonged antifungal therapy

(2015) Li Zhang et al.   BMC INFECTIOUS DISEASES

Homozygous deletion of ATC1 and NTC1 genes in Candida parapsilosis abolishes trehalase activity and affects cell growth, sugar metabolism, stress resistance, infectivity and biofilm formation

(2015) Ruth Sánchez-Fresneda et al.   FUNGAL GENETICS AND BIOLOGY

How to bolster the antifungal pipeline

(2015) D. W. Denning et al.   SCIENCE

The Production of Reactive Oxygen Species Is a Universal Action Mechanism of Amphotericin B against Pathogenic Yeasts and Contributes to the Fungicidal Effect of This Drug

(2014) Ana Cecilia Mesa-Arango et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The HOG Pathway Is Critical for the Colonization of the Mouse Gastrointestinal Tract by Candida albicans

(2014) Daniel Prieto et al.   PLoS One

Epidemiology and Outcomes of Invasive Candidiasis Due to Non-albicans Species of Candida in 2,496 Patients: Data from the Prospective Antifungal Therapy (PATH) Registry 2004–2008

(2014) Michael A. Pfaller et al.   PLoS One

Comparative Phenotypic Analysis of the Major Fungal Pathogens Candida parapsilosis and Candida albicans

(2014) Linda M. Holland et al.   PLoS Pathogens

Fungicidal Drugs Induce a Common Oxidative-Damage Cellular Death Pathway

(2013) Peter Belenky et al.   Cell Reports

Relevance of Trehalose in Pathogenicity: Some General Rules, Yet Many Exceptions

(2013) Hélène Tournu et al.   PLoS Pathogens

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Prospective Multicenter Study of the Epidemiology, Molecular Identification, and Antifungal Susceptibility of Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis Isolated from Patients with Candidemia

(2011) Emilia Cantón et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Amphotericin B induces trehalose synthesis and simultaneously activates an antioxidant enzymatic response in Candida albicans

(2011) Pilar González-Párraga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Amphotericin B mediates killing in Cryptococcus neoformans through the induction of a strong oxidative burst

(2011) Fernanda Sangalli-Leite et al.   MICROBES AND INFECTION

Epidemiology of Invasive Mycoses in North America

(2010) Michael A. Pfaller et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Phylogenetic diversity of stress signaling pathways in fungi

(2009) Elissavet Nikolaou et al.   BMC EVOLUTIONARY BIOLOGY

The three trehalases Nth1p, Nth2p and Ath1p participate in the mobilization of intracellular trehalose required for recovery from saline stress in Saccharomyces cerevisiae

(2009) E. Garre et al.   MICROBIOLOGY-SGM

Candida parapsilosis, an Emerging Fungal Pathogen

(2008) D. Trofa et al.   CLINICAL MICROBIOLOGY REVIEWS

Renal impairment and Amphotericin B formulations in patients with invasive fungal infections

(2008) Faouzi Saliba et al.   MEDICAL MYCOLOGY