A transmembrane C-terminal fragment of syndecan-1 is generated by the metalloproteinase ADAM17 and promotes lung epithelial tumor cell migration and lung metastasis formation

Methods for detection of circulating cells in non-small cell lung cancer

(2014) Yi Han   Frontiers in Bioscience-Landmark

Cytoplasmic Domain Interactions of Syndecan-1 and Syndecan-4 with α6β4 Integrin Mediate Human Epidermal Growth Factor Receptor (HER1 and HER2)-dependent Motility and Survival

(2014) Haiyao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping of matrix metalloproteinase cleavage sites on syndecan-1 and syndecan-4 ectodomains

(2013) Tina Manon-Jensen et al.   FEBS Journal

Syndecan-1 modulates β-integrin-dependent and interleukin-6-dependent functions in breast cancer cell adhesion, migration, and resistance to irradiation

(2013) Hebatallah Hassan et al.   FEBS Journal

Trimeric Tn Antigen on Syndecan 1 Produced by ppGalNAc-T13 Enhances Cancer Metastasis via a Complex Formation with Integrin α5β1 and Matrix Metalloproteinase 9

(2013) Yasuyuki Matsumoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen

(2012) Yasuyuki Matsumoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Syndecans play dual roles as cell adhesion receptors and docking receptors

(2012) Mi-Jung Kwon et al.   FEBS LETTERS

Sdc1 Overexpression Inhibits the p38 MAPK Pathway and Lessens Fibrotic Ventricular Remodeling in MI Rats

(2012) Juan Lei et al.   INFLAMMATION

Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism

(2012) Sherif A. Ibrahim et al.   INTERNATIONAL JOURNAL OF CANCER

Syndecan-1 Enhances Proliferation, Migration and Metastasis of HT-1080 Cells in Cooperation with Syndecan-2

(2012) Bálint Péterfia et al.   PLoS One

Molecular functions of syndecan-1 in disease

(2011) Yvonne Hui-Fang Teng et al.   MATRIX BIOLOGY

Cannabinoid Receptors, CB1 and CB2, as Novel Targets for Inhibition of Non-Small Cell Lung Cancer Growth and Metastasis

(2010) A. Preet et al.   Cancer Prevention Research

Proteoglycans in health and disease: the multiple roles of syndecan shedding

(2010) Tina Manon-Jensen et al.   FEBS Journal

ADAM17 Activity and Other Mechanisms of Soluble L-selectin Production during Death Receptor-Induced Leukocyte Apoptosis

(2010) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

The Tiam1 PDZ Domain Couples to Syndecan1 and Promotes Cell–Matrix Adhesion

(2010) Tyson R. Shepherd et al.   JOURNAL OF MOLECULAR BIOLOGY

Syndecans as cell surface receptors: Unique structure equates with functional diversity

(2010) Youngsil Choi et al.   MATRIX BIOLOGY

ADAM17-mediated shedding of the IL6R induces cleavage of the membrane stub by γ-secretase

(2009) Athena Chalaris et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Disintegrin and Metalloproteinase 17 (ADAM17) Mediates Inflammation-induced Shedding of Syndecan-1 and -4 by Lung Epithelial Cells

(2009) Jessica Pruessmeyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Syndecan-1 regulates αvβ3and αvβ5integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor

(2009) DeannaLee M. Beauvais et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ADAM10 Regulates Endothelial Permeability and T-Cell Transmigration by Proteolysis of Vascular Endothelial Cadherin

(2008) Beate Schulz et al.   CIRCULATION RESEARCH

A Genecentric Human Protein Atlas for Expression Profiles Based on Antibodies

(2008) Lisa Berglund et al.   MOLECULAR & CELLULAR PROTEOMICS