Regulation and function of the NFE2 transcription factor in hematopoietic and non-hematopoietic cells

Rho kinase inhibition drives megakaryocyte polyploidization and proplatelet formation throughMYCandNFE2downregulation

(2014) Mauro P. Avanzi et al.   BRITISH JOURNAL OF HAEMATOLOGY

NFE2 regulates transcription of multiple enzymes in the heme biosynthesis pathway

(2014) L. Rheinemann et al.   HAEMATOLOGICA

Mechanisms underlying platelet function defect in a pedigree with familial platelet disorder with a predisposition to acute myelogenous leukemia: potential role for candidate RUNX1 targets

(2014) A. C. Glembotsky et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The Up-Regulation of miR-199b-5p in Erythroid Differentiation Is Associated with GATA-1 and NF-E2

(2014) Yuxia Li et al.   MOLECULES AND CELLS

Interferon-γ suppresses activin A/NF-E2 induction of erythroid gene expression through the NF-κB/c-Jun pathway

(2013) Wei-Hwa Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling

(2013) K. Kapralova et al.   BLOOD

Subcellular mislocalization of the transcription factor NF-E2 in erythroid cells discriminates prefibrotic primary myelofibrosis from essential thrombocythemia

(2013) K. Aumann et al.   BLOOD

The effects of GATA-1 and NF-E2 deficiency on bone biomechanical, biochemical, and mineral properties

(2013) Melissa A. Kacena et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MPN patients harbor recurrent truncating mutations in transcription factor NF-E2

(2013) Jonas S. Jutzi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcription factors in late megakaryopoiesis and related platelet disorders

(2013) M. R. Tijssen et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A role of NF-E2 in chronic inflammation and clonal evolution in essential thrombocythemia, polycythemia vera and myelofibrosis?

(2013) Hans C. Hasselbalch   LEUKEMIA RESEARCH

NF-E2 p45 Is Important for Establishing Normal Function of Platelets

(2013) R. Fujita et al.   MOLECULAR AND CELLULAR BIOLOGY

Novel Hematopoietic Target Genes in the NRF2-Mediated Transcriptional Pathway

(2013) Michelle R. Campbell et al.   Oxidative Medicine and Cellular Longevity

Elevated Nuclear Factor Erythroid-2 Levels Promote Epo-Independent Erythroid Maturation and Recapitulate the Hematopoietic Stem Cell and Common Myeloid Progenitor Expansion Observed in Polycythemia Vera Patients

(2013) Ruzhica Bogeska et al.   Stem Cells Translational Medicine

Efficacy of vorinostat in a murine model of polycythemia vera

(2012) H. Akada et al.   BLOOD

Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf

(2012) Y. Ono et al.   BLOOD

The HDAC inhibitor Givinostat modulates the hematopoietic transcription factors NFE2 and C-MYB in JAK2V617F myeloproliferative neoplasm cells

(2012) Ariel Amaru Calzada et al.   EXPERIMENTAL HEMATOLOGY

Abnormal differentiation of erythroid precursors in p45 NF-E2−/− mice

(2012) Jadwiga J. Gasiorek et al.   EXPERIMENTAL HEMATOLOGY

A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2

(2012) Kai B. Kaufmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phosphorylation-Dependent SUMOylation of the Transcription Factor NF-E2

(2012) Yee-Fun Su et al.   PLoS One

p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth

(2011) M. Kashif et al.   DEVELOPMENT

Nuclear Factor Erythroid-derived 2 (Nfe2) Regulates JunD DNA-binding Activity via Acetylation

(2011) Muhammed Kashif et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The distinctive roles of erythroid specific activator GATA-1 and NF-E2 in transcription of the human fetal γ-globin genes

(2011) Yea Woon Kim et al.   NUCLEIC ACIDS RESEARCH

AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2

(2010) W. Wang et al.   BLOOD

USF and NF-E2 Cooperate to Regulate the Recruitment and Activity of RNA Polymerase II in the β-Globin Gene Locus

(2010) Zhuo Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A monopartite sequence is essential for p45 NF-E2 nuclear translocation, transcriptional activity and platelet production

(2010) J. PERDOMO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Genetic Analysis of Hierarchical Regulation for Gata1 and NF-E2 p45 Gene Expression in Megakaryopoiesis

(2010) Mariko Takayama et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular Determinants for Small Maf Protein Control of Platelet Production

(2010) H. Motohashi et al.   MOLECULAR AND CELLULAR BIOLOGY

NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation

(2009) H. Motohashi et al.   BLOOD

NF-E2 overexpression delays erythroid maturation and increases erythrocyte production

(2009) Manuel Mutschler et al.   BRITISH JOURNAL OF HAEMATOLOGY

JNK-mediated turnover and stabilization of the transcription factor p45/NF-E2 during differentiation of murine erythroleukemia cells

(2009) T.-L. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual role for the methyltransferase G9a in the maintenance of  -globin gene transcription in adult erythroid cells

(2009) C.-P. Chaturvedi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Itch regulates p45/NF-E2 in vivo by Lys63-linked ubiquitination

(2008) Tung-Liang Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NF-E2-mediated enhancement of megakaryocytic differentiation and platelet production in vitro and in vivo

(2007) Ee-ling Fock et al.   EXPERIMENTAL HEMATOLOGY

Small Maf Proteins in Mammalian Gene Control: Mere Dimerization Partners or Dynamic Transcriptional Regulators?

(2007) Volker Blank   JOURNAL OF MOLECULAR BIOLOGY