Physiological, pathological, and structural implications of non-enzymatic protein–protein interactions of the multifunctional human transglutaminase 2

Tissue Transglutaminase Activation Modulates Inflammation in Cystic Fibrosis via PPAR  Down-Regulation

(2014) L. Maiuri et al.   JOURNAL OF IMMUNOLOGY

GPR56 Inhibits Melanoma Growth by Internalizing and Degrading Its Ligand TG2

(2013) L. Yang et al.   CANCER RESEARCH

Transglutaminase 2-Specific Autoantibodies in Celiac Disease Target Clustered, N-Terminal Epitopes Not Displayed on the Surface of Cells

(2013) R. Iversen et al.   JOURNAL OF IMMUNOLOGY

The eukaryotic linear motif resource ELM: 10 years and counting

(2013) Holger Dinkel et al.   NUCLEIC ACIDS RESEARCH

Phosphorylation of transglutaminase 2 (TG2) at serine-216 has a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of PTEN

(2012) Yi Wang et al.   BMC CANCER

Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins

(2012) M D'Eletto et al.   CELL DEATH AND DIFFERENTIATION

Transglutaminase-2 Interaction with Heparin

(2012) Hugues Lortat-Jacob et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Heparin-binding Site of Tissue Transglutaminase

(2012) Zhuo Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transglutaminase 2 interaction with small heat shock proteins mediate cell survival upon excitotoxic stress

(2011) Daniela Caccamo et al.   AMINO ACIDS

Autoantibodies from patients with celiac disease inhibit transglutaminase 2 binding to heparin/heparan sulfate and interfere with intestinal epithelial cell adhesion

(2011) Kaupo Teesalu et al.   AMINO ACIDS

Bcr is a substrate for Transglutaminase 2 cross-linking activity

(2011) Sun-Ju Yi et al.   BMC BIOCHEMISTRY

Syndecan-4 signalling inhibits apoptosis and controls NFAT activity during myocardial damage and remodelling

(2011) Frank Echtermeyer et al.   CARDIOVASCULAR RESEARCH

Protein transamidation by transglutaminase 2 in cells: a disputed Ca2+-dependent action of a multifunctional protein

(2011) Róbert Király et al.   FEBS Journal

New insights into the functions and localization of nuclear transglutaminase 2

(2011) Ting-Fang Kuo et al.   FEBS Journal

Extracellular TG2: emerging functions and regulation

(2011) Alexey M. Belkin   FEBS Journal

Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

(2011) Lise Munsie et al.   HUMAN MOLECULAR GENETICS

A Unique Role for Heat Shock Protein 70 and Its Binding Partner Tissue Transglutaminase in Cancer Cell Migration

(2011) Lindsey K. Boroughs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isoaspartate-dependent molecular switches for integrin-ligand recognition

(2011) A. Corti et al.   JOURNAL OF CELL SCIENCE

Attributes of short linear motifs

(2011) Norman E. Davey et al.   Molecular BioSystems

A single conformational transglutaminase 2 epitope contributed by three domains is critical for celiac antibody binding and effects

(2011) Z. Simon-Vecsei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Significance of the Syndecan-4-Transglutaminase-2 Interaction

(2011) Elisabetta Verderio et al.   TheScientificWorldJOURNAL

Transglutaminase-2: a new endostatin partner in the extracellular matrix of endothelial cells

(2010) Clément Faye et al.   BIOCHEMICAL JOURNAL

Transglutaminase 2: A multi-tasking protein in the complex circuitry of inflammation and cancer

(2010) Kapil Mehta et al.   BIOCHEMICAL PHARMACOLOGY

Coeliac disease-specific autoantibodies targeted against transglutaminase 2 disturb angiogenesis

(2010) E. Myrsky et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease

(2010) Stephen J. McConoughey et al.   EMBO Molecular Medicine

Importance of syndecan-4 and syndecan -2 in osteoblast cell adhesion and survival mediated by a tissue transglutaminase−fibronectin complex

(2010) Z. Wang et al.   EXPERIMENTAL CELL RESEARCH

Redox Regulation of Transglutaminase 2 Activity

(2010) Jorunn Stamnaes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

(2010) Alessandro Luciani et al.   NATURE CELL BIOLOGY

Thermodynamics of binding of regulatory ligands to tissue transglutaminase

(2009) Carlo M. Bergamini et al.   AMINO ACIDS

HSP27: Mechanisms of Cellular Protection Against Neuronal Injury

(2009) R. Stetler et al.   CURRENT MOLECULAR MEDICINE

The interaction of angiocidin with tissue transglutaminase

(2009) Darryl Z. L’Heureux et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis

(2009) Róbert Király et al.   FEBS Journal

Transglutaminase 2 is expressed and active on the surface of human monocyte-derived dendritic cells and macrophages

(2009) Judit Hodrea et al.   IMMUNOLOGY LETTERS

Transglutaminase 2 Regulates the GTPase-activating Activity of Bcr

(2009) Sun-Ju Yi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Platelet-derived Growth Factor Receptor Function by Integrin-associated Cell Surface Transglutaminase

(2009) Evgeny A. Zemskov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparan Sulfate Proteoglycans Are Receptors for the Cell-surface Trafficking and Biological Activity of Transglutaminase-2

(2009) Alessandra Scarpellini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUMOylation of Tissue Transglutaminase as Link between Oxidative Stress and Inflammation

(2009) A. Luciani et al.   JOURNAL OF IMMUNOLOGY

Transglutaminase 2 Is Needed for the Formation of an Efficient Phagocyte Portal in Macrophages Engulfing Apoptotic Cells

(2009) B. Toth et al.   JOURNAL OF IMMUNOLOGY

Deamidated Gliadin Peptides Form Epitopes That Transglutaminase Antibodies Recognize

(2009) Ilma R Korponay-Szabó et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Transglutaminase II interacts with rac1, regulates production of reactive oxygen species, expression of snail, secretion of Th2 cytokines and mediates in vitro and in vivo allergic inflammation

(2009) Youngmi Kim et al.   MOLECULAR IMMUNOLOGY

Tissue specificity and the human protein interaction network

(2009) Alice Bossi et al.   Molecular Systems Biology

Enhanced osteoblast adhesion on transglutaminase 2-crosslinked fibronectin

(2008) J. Forsprecher et al.   AMINO ACIDS

Transdab wiki: the interactive transglutaminase substrate database on web 2.0 surface

(2008) Éva Csősz et al.   AMINO ACIDS

Tissue transglutaminase-induced down-regulation of matrix metalloproteinase-9

(2008) Jun-Seok Ahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transglutaminases and Transglutaminase-Catalyzed Cross-Links Colocalize with the Pathological Lesions in Alzheimer's Disease Brain

(2008) Micha M.M. Wilhelmus et al.   BRAIN PATHOLOGY

Tissue Transglutaminase Regulates Focal Adhesion Kinase/AKT Activation by Modulating PTEN Expression in Pancreatic Cancer Cells

(2008) A. Verma et al.   CLINICAL CANCER RESEARCH

The role of integrin binding sites in fibronectin matrix assembly in vivo

(2008) Michael Leiss et al.   CURRENT OPINION IN CELL BIOLOGY

Transglutaminase 2 protects against ischemic insult, interacts with HIF1β, and attenuates HIF1 signaling

(2008) Anthony J. Filiano et al.   FASEB JOURNAL

Extracellular transglutaminase 2 activates β-catenin signaling in calcifying vascular smooth muscle cells

(2008) Lidia Faverman et al.   FEBS LETTERS

Fibronectin-Tissue Transglutaminase Matrix Rescues RGD-impaired Cell Adhesion through Syndecan-4 and β1Integrin Co-signaling

(2008) Dilek Telci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronic acid targets CD44 and inhibits FcɛRI signaling involving PKCδ, Rac1, ROS, and MAPK to exert anti-allergic effect

(2008) Youngmi Kim et al.   MOLECULAR IMMUNOLOGY

The Monoclonal Antibody 6B9 Recognizes CD44 and Not Cell Surface Transglutaminase 2

(2008) J. Stamnaes et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY