Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein

Testosterone Replacement Therapy in Older Male Subjective Memory Complainers: Double-Blind Randomized Crossover Placebo-Controlled Clinical Trial of Physiological Assessment and Safety

(2015) Prita Asih et al.   CNS & Neurological Disorders-Drug Targets

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

Oophorectomy, estrogen, and dementia: A 2014 update

(2014) Walter A. Rocca et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Parkinsonian syndrome in familial frontotemporal dementia

(2014) Joanna Siuda et al.   PARKINSONISM & RELATED DISORDERS

Actions of 17β-estradiol and testosterone in the mitochondria and their implications in aging

(2013) Andrea Vasconsuelo et al.   AGEING RESEARCH REVIEWS

The global prevalence of dementia: A systematic review and metaanalysis

(2013) Martin Prince et al.   Alzheimers & Dementia

The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives

(2013) Russell H. Swerdlow et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Estradiol and Testosterone Regulate Arginine-Vasopressin Expression in SH-SY5Y Human Female Neuroblastoma Cells Through Estrogen Receptors-α and -β

(2013) Daniela Grassi et al.   ENDOCRINOLOGY

Ligand for Translocator Protein Reverses Pathology in a Mouse Model of Alzheimer's Disease

(2013) A. M. Barron et al.   JOURNAL OF NEUROSCIENCE

In vivo functional brain mapping in a conditional mouse model of human tauopathy (taup301l) reveals reduced neural activity in memory formation structures

(2013) Pablo D Perez et al.   Molecular Neurodegeneration

17β-Estradiol and Progesterone Regulate Expression of β-Amyloid Clearance Factors in Primary Neuron Cultures and Female Rat Brain

(2012) Anusha Jayaraman et al.   ENDOCRINOLOGY

Gender, sex steroid hormones, and Alzheimer's disease

(2012) Rebekah S. Vest et al.   HORMONES AND BEHAVIOR

Sex Steroid Levels and AD-Like Pathology in 3xTgAD Mice

(2012) C. R. Overk et al.   JOURNAL OF NEUROENDOCRINOLOGY

A New Link to Mitochondrial Impairment in Tauopathies

(2012) Kathrin L. Schulz et al.   MOLECULAR NEUROBIOLOGY

Alzheimer's Disease, Oestrogen and Mitochondria: an Ambiguous Relationship

(2012) Amandine Grimm et al.   MOLECULAR NEUROBIOLOGY

Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer’s disease

(2012) G Verdile et al.   MOLECULAR PSYCHIATRY

Insights into Mitochondrial Dysfunction: Aging, Amyloid-β, and Tau–A Deleterious Trio

(2011) Karen Schmitt et al.   ANTIOXIDANTS & REDOX SIGNALING

Brain aging, Alzheimer's disease, and mitochondria

(2011) Russell H. Swerdlow   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Modes of Aβ toxicity in Alzheimer’s disease

(2011) Jürgen Götz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice

(2011) Magali Dumont et al.   FASEB JOURNAL

Milestones on Steroids and the Nervous System: 10 Years of Basic and Translational Research

(2011) G. C. Panzica et al.   JOURNAL OF NEUROENDOCRINOLOGY

Estrogen induces neurite outgrowth via Rho family GTPases in neuroblastoma cells

(2011) Kazuhiro Takahashi et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid

(2011) Jia Yao et al.   NEUROBIOLOGY OF AGING

Allopregnanolone Promotes Regeneration and Reduces β-Amyloid Burden in a Preclinical Model of Alzheimer's Disease

(2011) Shuhua Chen et al.   PLoS One

Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity

(2011) Anne Eckert et al.   Alzheimers Research & Therapy

Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease

(2010) Lisa Mosconi et al.   Annals of the New York Academy of Sciences

Women Live Longer than Men: Understanding Molecular Mechanisms Offers Opportunities to Intervene by Using Estrogenic Compounds

(2010) Jose Viña et al.   ANTIOXIDANTS & REDOX SIGNALING

Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways

(2010) Emily R. Rosario et al.   BRAIN RESEARCH

Sex differences in β-amyloid accumulation in 3xTg-AD mice: Role of neonatal sex steroid hormone exposure

(2010) Jenna C. Carroll et al.   BRAIN RESEARCH

Neuroprotective mechanism conferred by 17beta-estradiol on the biochemical basis of Alzheimer's disease

(2010) Z. Amtul et al.   NEUROSCIENCE

Ginkgo Biloba Extract Ameliorates Oxidative Phosphorylation Performance and Rescues Aβ-Induced Failure

(2010) Virginie Rhein et al.   PLoS One

Aβ and human amylin share a common toxicity pathwayviamitochondrial dysfunction

(2010) Yun-An Lim et al.   PROTEOMICS

Amyloid-beta Leads to Impaired Cellular Respiration, Energy Production and Mitochondrial Electron Chain Complex Activities in Human Neuroblastoma Cells

(2009) V. Rhein et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Protective actions of sex steroid hormones in Alzheimer’s disease

(2009) Christian J. Pike et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimer's disease

(2009) Emily R. Rosario et al.   NEUROBIOLOGY OF AGING

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-  and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

(2009) V. Rhein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Refining Frontotemporal Dementia With Parkinsonism Linked to Chromosome 17

(2008) Bradley F. Boeve et al.   ARCHIVES OF NEUROLOGY

Progesterone and Estrogen Regulate Oxidative Metabolism in Brain Mitochondria

(2008) Ronald W. Irwin et al.   ENDOCRINOLOGY

Estradiol Attenuates Tau Hyperphosphorylation Induced by Upregulation of Protein Kinase-A

(2008) Xin-An Liu et al.   NEUROCHEMICAL RESEARCH

Mitochondria in Neuroplasticity and Neurological Disorders

(2008) Mark P. Mattson et al.   NEURON