Review
Biochemistry & Molecular Biology
Codrin-Constantin Burlacu, Daniela Ciobanu, Andrei-Vlad Badulescu, Vlad-Florin Chelaru, Andrei-Otto Mitre, Bogdan Capitanescu, Dirk M. Hermann, Aurel Popa-Wagner
Summary: Stroke is the second leading cause of death and disability, with limited therapeutic strategies. Blood-based biomarkers, such as microRNAs and exosomes, are recognized as useful tools to predict prognosis in patients with stroke. This systematic review identified 72 circulating biomarkers with prognostic value in stroke recovery, including 68 miRNAs predictive for motor recovery and seven biomarkers predictive for cognitive recovery. The most significant correlations were found with miR-21, miR-29b, miR-125b-5p, miR-126, and miR-335. Serum miR-9 and neutrophil miR-29b were identified as promising biomarkers for further studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Medicine, General & Internal
Yang Wang, Xianwei Su, Geoffrey Ho Duen Leung, Baohua Ren, Qiang Zhang, Zhiqiang Xiong, Jingye Zhou, Ling Yang, Gang Lu, Wai-Yee Chan, Lijie Ren
Summary: This study conducted comprehensive analysis and real-world validation to assess the association between circulating miRNAs and ischemic stroke (IS). The results showed that 4 miRNAs exhibited significant expression levels in IS patients, suggesting potential circulating diagnostic or therapeutic targets for IS patients.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
(2023)
Article
Neurosciences
Liyun Wang, Xiaoxing Xiong, Luyuan Zhang, Jian Shen
Summary: Ischemic stroke, resulting from sudden blockage of brain blood vessels, has a significant impact on health. Recent studies have highlighted the influence of the neurovascular unit on stroke outcomes, providing new strategies for treatment. The pathophysiology and neurovascular repair processes of IS are closely linked to the homeostatic state of the NVU, suggesting potential expansions in treatment options.
CNS NEUROSCIENCE & THERAPEUTICS
(2021)
Review
Neurosciences
Xiao Zhang, Mengyao Wan, Xiaoli Min, Guanglei Chu, Yumin Luo, Ziping Han, Wei Li, Ran Xu, Jichang Luo, Wenjing Li, Yutong Yang, Yan Ma, Liqun Jiao, Tao Wang
Summary: This study aims to identify circRNAs as potential biomarkers for acute ischemic stroke (AIS) by analyzing published literature. The researchers found that circRNAs have potential discriminative ability in the diagnosis of AIS and identified several circRNAs that may serve as biomarkers for AIS.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Review
Endocrinology & Metabolism
Josie L. Fullerton, Josephine M. Thomas, Laura Gonzalez-Trueba, Cara Trivett, Josie C. van Kralingen, Stuart M. Allan, Terence J. Quinn, Lorraine M. Work
Summary: This systematic review aimed to assess the range and quality of clinical and preclinical evidence supporting the association of individual microRNAs and their use in the diagnosis and prognosis of ischaemic or haemorrhagic stroke. The findings highlighted specific microRNAs that consistently showed differential expression in both clinical and preclinical samples following stroke. However, further studies with larger populations and consistent methodologies are needed to confirm the clinical value of circulating microRNAs as biomarkers for stroke.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2022)
Review
Biochemistry & Molecular Biology
Oscar Salvador Barrera-Vazquez, Juan Carlos Gomez-Verjan, Ricardo Ramirez-Aldana, Paola Garcia-dela Torre, Nadia Alejandra Rivero-Segura
Summary: This study conducted a systematic review of literature from 2015-2021 to analyze and identify the most common microRNAs expressed during acute ischemic stroke (AIS), as well as the pathways, genes, and compounds that influence their expression. The study identified two sets of microRNAs associated with AIS and revealed a network of toxicants and drugs related to AIS for the first time.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Clinical Neurology
Zhengbao Zhu, Daoxia Guo, Kaixin Zhang, Pinni Yang, Yiming Jia, Mengyao Shi, Yanbo Peng, Jing Chen, Aili Wang, Tan Xu, Yonghong Zhang, Jiang He
Summary: Plasma osteoprotegerin is associated with poor prognosis of ischemic stroke. High levels of plasma osteoprotegerin are associated with increased risk of death and major disability. Genetically determined high plasma osteoprotegerin is associated with an increased risk of primary outcome.
Article
Oncology
Yuwei Xie, Yixiu Wang, Weijie Xue, Hao Zou, Kun Li, Kui Liu, Wei Zhao, Chengzhan Zhu, Jingyu Cao
Summary: This study investigated differentially expressed RNA profiles in hepatocellular carcinoma (HCC) and identified several miRNAs, such as Hsa-miR-1269a and Hsa-miR-421, that are associated with the development and prognosis of HCC.
FRONTIERS IN ONCOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Timea Forro, Zoltan Bajko, Adrian Balasa, Rodica Balasa
Summary: Ischemic stroke is a severe global cerebral vascular disease with high disability and mortality rates, where the neurovascular unit (NVU) plays a crucial role. Exosomes mediate cell-to-cell communication within the NVU, with clinical trials showing significant diagnostic and prognostic roles of exosomes in stroke patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Chemistry, Medicinal
Dan Luo, Baili Yu, Shoukai Sun, Bonan Chen, Harsh Vivek Harkare, Longlong Wang, Jie Pan, Bin Huang, Yang Song, Tianhong Ma, Shihua Shi
Summary: We conducted a meta-analysis on the clinical efficacy of berberine (BBR) in treating acute ischemic stroke (AIS) and its anti-inflammatory effects. The analysis included 17 clinical trials involving 1670 AIS patients. The results showed that BBR in combination with conventional treatment significantly reduced inflammatory markers and improved outcomes compared to conventional treatment alone.
PHYTOTHERAPY RESEARCH
(2023)
Article
Clinical Neurology
Sauson Soldozy, Kaan Yagmurlu, Pedro Norat, Mazin Elsarrag, John Costello, Faraz Farzad, Jennifer D. Sokolowski, Khadijeh A. Sharifi, Turki Elarjani, Joshua Burks, Petr Tvrdik, Mark E. Shaffrey, Min S. Park, Robert M. Starke, Errol Gordon, M. Yashar S. Kalani
Summary: This study systematically reviewed the usefulness of serum biomarkers in predicting long-term outcome after ischemic stroke (IS). The analysis identified C-reactive protein, albumin, copeptin, and D-dimer to be significantly associated with long-term outcome. These serum biomarkers, combined with imaging biomarkers and used in artificial intelligence algorithms, can provide refined predictive outcomes.
WORLD NEUROSURGERY
(2022)
Article
Cell Biology
Jiali Tao, Xiaochen Xie, Man Luo, Qingsong Sun
Summary: By using various methods including dimensionality reduction cluster analysis, differential expression analysis, and protein-protein interaction network analysis, this study identified cell heterogeneity and key pathogenic genes in ischemic stroke. Immunomicroenvironment analysis was used to explore the immune landscape and immune associations of these genes. PCR experiments confirmed the expression of key genes. These findings provide a reference for the study of pathogenesis and key targets in ischemic stroke.
Article
Neurosciences
Miao Lv, Wanting He, Tian Liang, Jialei Yang, Xiaolan Huang, Shengying Liu, Xueying Liang, Jianxiong Long, Li Su
Summary: Through bioinformatics analysis, we identified potential diagnostic biomarkers and gene-drug interactions associated with ischemic stroke, which can contribute to the diagnosis and treatment of stroke.
Review
Biochemistry & Molecular Biology
Lazzaro di Biase, Adriano Bonura, Pasquale Maria Pecoraro, Simona Paola Carbone, Vincenzo Di Lazzaro
Summary: Stroke, a complex and heterogeneous disease, poses challenges for early diagnosis and treatment due to the lack of specific diagnostic biomarkers. This review identifies four promising biomarkers for early diagnosis, differentiation between ischemic and hemorrhagic stroke, and prediction of hemorrhagic transformation. Integration of these biomarkers could significantly improve stroke patients' detection and treatment. However, further research and validation are needed to demonstrate their clinical utility in routine stroke treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Clinical Neurology
Jiejie Li, Yuesong Pan, Jie Xu, Shiyu Li, Mengxing Wang, Kehua Quan, Xia Meng, Hao Li, Jinxi Lin, Yilong Wang, Xingquan Zhao, Liping Liu, Yongjun Wang
Summary: Residual inflammatory risk only may predict recurrent stroke and poor functional outcome in patients with acute ischemic stroke or transient ischemic attack, especially in those with large-artery atherosclerosis.
Article
Biotechnology & Applied Microbiology
Dong Cao, Fahui Ye, Caixia Zhao, Jicheng Shen, Ruijuan Liu, Bo Zhang, Yuhu Shen, Huaigang Zhang, Baolong Liu, Wenjie Chen
Summary: Avenin-like storage proteins have a significant impact on the rheological properties and processing quality of common wheat. The study on variability in avenin-like b genes in T. urartu revealed high levels of polymorphism, resulting in the discovery of 18 novel TuALPb7A alleles. These alleles can improve the functional properties of dough and provide breeding materials for wheat quality improvement.
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
(2021)
Article
Gastroenterology & Hepatology
Morteza Hafezi, Meiyin Lin, Adeline Chia, Alicia Chua, Zi Zong Ho, Royce Fam, Damien Tan, Joey Aw, Andrea Pavesi, Thinesh Lee Krishnamoorthy, Wan Cheng Chow, Wenjie Chen, Qi Zhang, Lu-En Wai, Sarene Koh, Anthony T. Tan, Antonio Bertoletti
Summary: The study engineered TCR-T cells of desired specificities that transiently resist the immunosuppressive effects of TAC and MMF, providing a new clinical application for treating HBV-HCC relapses and other pathologies occurring in organ transplanted patients.
Article
Engineering, Multidisciplinary
Xiantao Sun, Wenjie Chen, Weihai Chen, Ying Zhang, Jun Jiang, Cungang Hu, Jun Tao
Summary: This paper presents a design method for a large-range torque sensor with variable resolutions based on the principle of variable stiffness. The sensor, constructed by multiple radial flexures with different stiffness in series, can provide variable resolutions in different ranges. Additionally, a passive eddy current damper is designed to suppress mechanical vibration, and experimental results show excellent vibration suppression performance of the sensor.
Article
Environmental Sciences
Bo Shao, Xu Tan, Ju-Long Li, Mei He, Lei Tian, Wen-Jie Chen, Yan Lin
Summary: The synergistic effects of plant-microbial treatment significantly enhance the removal of pollutants in shale gas fracturing waste fluid. The combination of 201.24g water dropwort and 435mg/L activated sludge under illumination of 450-495 nm (blue) at 25 degrees Celsius showed the best treatment condition. The microbial community composition varied significantly with illumination wavelength and temperature under plant-microbial synergism.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Medicine, General & Internal
Wen Li, Yunfu Deng, Qiang Wu, Wenjie Chen, Zhengkun Liu, Ting Wang, Cheng Ai, Fang Chen, Zhu Wang, Guangzhi Ma, Qinghua Zhou
Summary: Younger age, PR negative status, tumor grade, and advanced lymph nodes postsurgery are independent prognostic factors of disease-free survival (DFS) and overall survival (OS) in young patients with resected breast cancer. In hormone receptor-positive patients, those with ER+ or PR+ and HER2-/+ status showed poorer prognosis. Risk factor grouping based on certain factors can identify patients with poorer prognosis in young breast cancer cases.
Article
Agriculture, Multidisciplinary
Ruijuan Liu, Mingze Xia, Demei Liu, Liling Jiang, Jicheng Shen, Wenjie Chen
Summary: This study reported the complete chloroplast genome sequences of Elymus nutans and Pseudoroegneria species, revealing their parental relationships, genome size, and composition characteristics. Through chloroplast genome analysis and Bayesian inference phylogenetic tree, it was determined that Pseudoroegneria cognata might be the main maternal genome donor of E. nutans in the Qinghai-Tibet Plateau.
Article
Automation & Control Systems
Jia Liu, Zhitao Liu, Wenjie Chen, Hongye Su, Liyan Zhang
Summary: This article investigates current sharing based on incremental passivity control for multilevel connected dc-dc converters. By combining passivity-based control with a finite-time estimator, a linear control law is proposed despite the bilinear nature of the system. Analysis shows that stability and current sharing are independent of inductor parameters. Simulation and experiments validate the proposed control scheme's fast transit response and antidisturbance performance.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2022)
Article
Engineering, Electrical & Electronic
Jia Liu, Zhitao Liu, Wenjie Chen, Xuhui Sun, Hongye Su
Summary: In this paper, a new magnetic coupler array is proposed to implement dynamic wireless charging and reduce power pulsation. By adjusting the transmitter spacing and designing a larger receiver coil, power pulsation and null power phenomenon are successfully mitigated. Furthermore, a multilevel connected DC-DC converter is designed to regulate transfer power, and a passivity-based control method and current sharing compensator are developed.
IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY
(2022)
Article
Automation & Control Systems
Haiyue Zhu, Xiong Li, Wenjie Chen, Xiaocong Li, Jun Ma, Chek Sing Teo, Tat Joo Teo, Wei Lin
Summary: This study presents a grasping control framework based on category-aware force regulation, utilizing a convolutional neural network for object classification and enabling a variable stiffness gripper to handle objects with diverse properties. The vision-based force sensing module allows for accurate force regulation without the need for additional force sensors.
IEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING
(2022)
Article
Multidisciplinary Sciences
Chen-Han Lin, Bhagyashree Senapati, Wen-Jie Chen, Sonia Bansal, Suewei Lin
Summary: The assembly process of extrinsic neurons in the Drosophila mushroom body (MB) is not well understood. In this study, the authors followed the development of DANs and MBONs in the adult MB and found that these neurons innervate the lobes sequentially and their neurite arborizations in the lobes are independent of each other. The dendrites of MBONs show a hierarchical organization of guidance signals.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Engineering, Multidisciplinary
Weihai Chen, Xiantao Sun, Wenjie Chen, Gang Xie, Shasha Chen, Jianhua Wang
Summary: Roll-to-roll printed electronics is a low-cost and high-efficiency manufacturing method that requires stable web tension control. Traditional control methods struggle to guarantee control accuracy due to uncertainties, hence a nonlinear model predictive control scheme is proposed to eliminate disturbances. The effectiveness of the proposed control scheme is validated through MATLAB simulations and performance tests.
PRECISION ENGINEERING-JOURNAL OF THE INTERNATIONAL SOCIETIES FOR PRECISION ENGINEERING AND NANOTECHNOLOGY
(2022)
Article
Automation & Control Systems
Weihai Chen, Libo Zhou, Jianhua Wang, Zheng Zhao, Wenjie Chen, Shaoping Bai
Summary: The article presents a novel hysteresis modeling method for a nonlinear stiffness compliant actuator, which can adjust the shape of torque curves according to different amplitudes. By adopting the concept of virtual deformation to transform the nonlinearity curve into a polyline-based model, it achieves reduced root-mean-square error and computation cost compared to the nonlinear backlash model.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2022)
Article
Automation & Control Systems
Xiantao Sun, Wenjie Chen, Xiaoyu Xiong, Weihai Chen, Yan Jin
Summary: This article presents a novel variable configuration approach to develop an adjustable-resolution force sensor with a compact force-sensitive structure. By measuring the displacement of the deformed structure using a precision optical linear encoder, the external force can be detected. The variable measuring range and force resolution are achieved through the continuous adjustment of structural stiffness.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2023)
Proceedings Paper
Automation & Control Systems
Xiaoyu Xiong, Xiantao Sun, Wenjie Chen, Yali Zhi, Xiaohan Fang
Summary: This paper proposes a variable stiffness actuator that can adjust the stiffness by regulating the spring stiffness and joint radius. Different from traditional antagonistic actuators, this approach decouples the stiffness control and position control, achieving a larger range of stiffness adjustment.
2022 IEEE/ASME INTERNATIONAL CONFERENCE ON ADVANCED INTELLIGENT MECHATRONICS (AIM)
(2022)
Article
Thermodynamics
Yanhong Sun, Wenjie Chen, Jinli Lu, Changlong Wang
Summary: In this study, experimental investigation on the flow and heat transfer characteristics of a thin liquid film in micro circular tubes with an inner diameter of 0.5 mm was conducted. The results showed that the temperature and pressure fluctuation was consistent with the generation of bubble clusters, providing insights into the mechanism of flow boiling instability. The characteristics of void fraction, such as the duration of bubbles and liquid slugs, were obtained from the dynamic distribution diagram of the liquid film thickness, and the experimental data showed a good agreement with the homogeneous model. The temporary variation of the thin liquid film offered an opportunity to probe the physics of bubble dynamics and instability during flow boiling.
THERMAL SCIENCE AND ENGINEERING PROGRESS
(2022)
Article
Neurosciences
Adam Vacek, Grant Mair, Philip White, Philip M. Bath, Keith W. Muir, Rustam Al-Shahi Salman, Chloe Martin, David Dye, Francesca M. Chappell, Ruediger von Kummer, Malcolm Macleod, Nikola Sprigg, Joanna M. Wardlaw
Summary: This study evaluated the performance of e-ASPECTS software in delineating the extent of intracranial hemorrhage (ICH) on brain CT scans. The results showed that the software achieved excellent or good delineation of ICH extent in 71% of cases. However, it was more likely to over- or under-estimate the extent when ICH was more extensive, intraventricular, or extra-axial.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Mathias Jacobsen Bach, Audrone Jakubauskaite, Ian Law, Otto Molby Henriksen, Inger Havsteen, Alexander Cuculiza Henriksen, Sverre Rosenbaum, Lisbeth Marner
Summary: This study found that the rCBFacz value after ACZ challenge can serve as an important indicator for predicting future cerebrovascular events, with high accuracy and prognostic value.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Tak Kyu Oh, Saeyeon Kim, In-Ae Song
Summary: The study found that many survivors of nontraumatic intracranial hemorrhage in South Korea experience unemployment, decreased household income, and newly acquired disability after intensive care unit admission. However, these changes are not associated with 2-year all-cause mortality.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Eduardo Sousa de Melo, Rodrigo de Paiva Bezerra, Arthur Cesario de Holanda, Maria Junia Lira e Silva, Paloma Peter Travassos, Tayne Fernanda Lemos da Silva, Genova Maria de Azevedo Oliveira, Silvia Marinho Martins Alves, Carolina de Araujo Medeiros, Maria das Neves Dantas da Silveira Barros, Wilson Alves de Oliveira, Gisele Sampaio Silva, Luciana Patrizia Alves de Andrade Valenca
Summary: Cardiac involvement has been found to be the predominant factor correlated with stroke in Chagas disease. While atherosclerosis-related risk factors are prevalent, their influence on ischemic stroke in Chagas disease appears limited.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Pingping Zheng, Ning Zhang, Zixi Chen
Summary: This case presents a rare infectious cause of stroke and air embolism involving a pulmonary abscess and pulmonary vein thrombosis. Early detection, diagnosis, and appropriate treatment of infected systemic embolism in young patients are crucial to prevent serious complications.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Filippo Luca Gurgoglione, Luigi Vignali, Maria Alberta Cattabiani, Emilia Solinas, Giorgio Benatti, Iacopo Tadonio, Federico Barocelli, Chiara Dizdari, Domenico Tuttolomondo, Diego Ardissino, Francesco Nicolini, Giampaolo Niccoli
Summary: The incidence of recurrent ischemic neurological events after transcatheter patent foramen ovale closure is relatively low. Obesity, Risk of Paradoxical Embolism score < 7, and migraine are independent positive predictors of recurrent stroke or transient ischemic attack.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Angelo Cascio Rizzo, Ghil Schwarz, Amedeo Cervo, Giuditta Giussani, Chiara Ceresa, Antonella Gatti, Fausto De Angeli, Cristina Motto, Angelo Guccione, Rachele Tortorella, Giuseppe Granata, Claudia Rollo, Antonio Macera, Mariangela Piano, Guglielmo Pero, Elio Clemente Agostoni
Summary: This study aimed to evaluate the efficacy and safety of endovascular treatment (EVT) in primary and EVT-induced secondary medium-vessel occlusions (MeVO). The results showed that primary MeVO had poorer outcomes in terms of complications, EVT efficacy, and the proportion of patients with a modified Rankin Scale (mRS) of 0-2 at 3 months compared to exclusive large-vessel occlusion (LVO). However, EVT-induced secondary MeVO showed similar safety and efficacy outcomes as exclusive LVO and had better outcomes in terms of mRS 0-2 compared to primary MeVO.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jing Zhang, Chenming Wei, Jian Wu
Summary: This case report describes a patient with Bloom syndrome who developed acute cerebral infarction along with elevated antiphospholipid antibodies, suggesting a possible association between immune and coagulation abnormalities caused by Bloom syndrome and the development of acute cerebral infarction.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Yunxia Zhou, Shenglan He, Yanhong Hu
Summary: Compared with clopidogrel, DAPT with ticagrelor plus aspirin was associated with significantly lower thromboembolic events without an increase in hemorrhagic events in the treatment of intracranial aneurysms, according to the one-year clinical outcome analysis. However, larger upcoming trials are needed to confirm the effectiveness and safety of ticagrelor-associated DAPT.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Edvania Andrade de Moura Silva, Ludmilla Ribeiro Batista, Marcela Aline Fernandes Braga, Luci Fuscaldi Teixeira-Salmela, Christina Danielli Coelho de Morais Faria, Iza Faria-Fortini
Summary: The study found that stroke severity is the best predictor of self-perceived manual ability at both three and six months after stroke. Age, although significant, contributes little to the prediction of manual ability.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Sidarrth Prasad, Erica M. Jones, Mehari Gebreyohanns, Veronica Aguilera, DaiWai M. Olson, Jane A. Anderson, Sean I. Savitz, Salvador C. Flores, Steven J. Warach, Charlotte E. Rhodes, Mark P. Goldberg, Nneka L. Ifejika
Summary: This study identified the barriers and facilitators to adopting tenecteplase (TNK) as a thrombolytic treatment for acute ischemic stroke (AIS) by conducting qualitative research with stroke clinicians in Texas. The findings suggest that providing evidence and identifying key change processes can help clinicians achieve consensus on adopting TNK for AIS treatment.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jeshma Jayan, Sunil K. Narayan, Yasmin Nesha Haniffa, Navin Kumar
Summary: This study investigated the effects of transcranial electrical and magnetic stimulation on somatosensory evoked potentials in chronic ischemic stroke patients, finding that the real tDCS and rTMS combination results in significant improvement and is safe for use.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Phoebe M. Tran, Cenjing Zhu, William T. Harris II, Sajeesh K. Kamala Raghavan, Agricola Odoi, Liem Tran
Summary: This study assessed the geographic accessibility of stroke rehabilitation facilities in Tennessee. The study found that rural counties had significantly longer travel distances and times compared to urban counties. Counties with high and medium stroke prevalence also had higher travel times and distances compared to low stroke prevalence counties. Therefore, addressing transportation barriers and implementing tele-rehabilitation are crucial for improving access to stroke aftercare in these areas.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Lili Xu, Shuaiyu Chen, Jing Xu, Yanyan Shi, Zhihang Huang, Meng Wang, Ziqiao Wei, Hui Cao, Junshan Zhou, Wei Wang, Mingyang Du
Summary: This study found that the Chinese Visceral Adiposity Index (CVAI) is positively correlated with 90-day poor outcome in Chinese ischemic stroke patients after endovascular thrombectomy (EVT).
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Guangying Wu, Shuhua Li, Min Luo, Xiaotian Li, Xinghua Zhu, Junhuai Zhang, Qian He, Qian Yang, Guojiang Zhao, Shasha Luo, Zhijie Yang
Summary: The study aimed to investigate the relationship between serum alkaline phosphatase (ALP) levels and the severity and prognosis of intracerebral hemorrhage (ICH). The results showed that serum ALP levels in ICH patients were significantly elevated and correlated with hematoma volume and Glasgow coma scale (GCS) score. High serum ALP levels may serve as a potential predictor for the severity and unfavorable prognosis of ICH.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)