Article
Geriatrics & Gerontology
Yawen Yang, Huijuan Pan, Wenxiu Pan, Yang Liu, Xiaohui Song, Chuanxin M. Niu, Wuwei Feng, Jixian Wang, Qing Xie
Summary: The study showed that the combination of rTMS and hand grip training resulted in significant improvements in neurobehavioral and hand functional recovery compared to rTMS alone or hand grip training alone. However, there were no significant differences in neurophysiologic outcomes between intra-groups and inter-groups.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Rehabilitation
Yan Gong, Xian-Ming Long, Ying Xu, Xiu-Ying Cai, Ming Ye
Summary: The study demonstrated that 1Hz rTMS combined with anodal tDCS stimulation protocol showed significant effects on motor function and cortex excitability in subacute stroke patients, making it a potential preferred rehabilitative strategy for motor recovery.
CLINICAL REHABILITATION
(2021)
Article
Clinical Neurology
Jongwook Kim, Byoungwoo Cha, Doyoung Lee, Jong Moon Kim, MinYoung Kim
Summary: High-frequency rTMS over the ipsilesional DLPFC has beneficial effects on cognition and mood recovery in patients with subacute stroke. The improvement in cognitive abilities is more significant in patients with left hemispheric lesions, while patients with right hemispheric lesions show greater improvement in cognition.
FRONTIERS IN NEUROLOGY
(2022)
Review
Geriatrics & Gerontology
Abdulhameed Tomeh, Abdul Hanif Khan Yusof Khan, Wan Aliaa Wan Sulaiman
Summary: Stroke is a major cause of disability and death among the elderly population. Restoring blood circulation in the early phase of stroke is crucial for protecting neurons. Rehabilitation techniques can help stroke survivors regain their affected functions, and transcranial magnetic stimulation (TMS) has emerged as a novel method to aid in this process. TMS can be used to assess and modulate cortical excitability non-invasively, and repetitive TMS (rTMS) of the primary motor cortex (M1) shows promising results in post-stroke motor rehabilitation. It has also been found to have potential therapeutic uses in treating other symptoms such as dysphagia, speech impairments, central post-stroke pain, depression, and cognitive dysfunction.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Clinical Neurology
Hee-Mun Cho, Seungwoo Cha, Min Kyun Sohn, Sungju Jee, Won Kee Chang, Won-Seok Kim, Nam-Jong Paik
Summary: This study aims to investigate the efficacy of low-frequency rTMS in the motor function recovery of the upper limb in patients with subcortical and brainstem ischemic stroke. The study design is a multi-center, double-blind, randomized controlled trial comparing real rTMS with sham stimulation. The efficacy will be evaluated using various assessment measures, including BBT and UE-FMA.
FRONTIERS IN NEUROLOGY
(2023)
Article
Neurosciences
Xiaofang Wu, Rui Wang, Qunqiang Wu, Chunhua Liao, Jianshe Zhang, Huiduo Jiao, Baolin Chen, Shuyan Wang, Rui Liu
Summary: Upper limb motor impairments after stroke severely impact the quality of life of patients and their families. Transcranial magnetic stimulation (TMS) has been shown to be effective in promoting upper limb motor recovery. This study investigated the combined effect of high frequency repetitive TMS and cervical nerve root magnetic stimulation on functional improvement in stroke patients.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Clinical Neurology
Yu-Ting Hu, Xi-Wen Hu, Jin-Fang Han, Jian-Feng Zhang, Ying-Ying Wang, Annemarie Wolff, Sara Tremblay, Dusan Hirjak, Zhong-Lin Tan, Georg Northoff
Summary: This study compared the therapeutic efficacy of rTMS at the left motor cortex (lMC) and left dorsolateral prefrontal cortex (lDLPFC) in MDD patients. The results showed no significant difference in treatment outcomes and tolerability between the two groups. The findings suggest that lMC can be a potential and easily accessible rTMS target.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Jessica Borges Kroth, Benjamim Handfas, Glaucia Rodrigues, Francisco Zepeda, Marco Aurelio Oliveira, Danny J. J. Wang, Raymundo Machado de Azevedo Neto, Gisele Sampaio Silva, Edson Amaro, Isaac Olubunmi Sorinola, Adriana Bastos Conforto
Summary: This study aims to compare the effects of RPSS on upper limb motor performance and learning in stroke patients at different stages, as well as investigate its impact on brain perfusion, functional imaging activation, and GABA levels. The results will inform future clinical trials on tailoring RPSS for patients who are more likely to benefit from this intervention.
FRONTIERS IN NEUROLOGY
(2022)
Article
Medicine, General & Internal
Ji Hye Kang, Min-Wook Kim, Kyoung Ha Park, Young-Ah Choi
Summary: The study showed that LF rTMS + MI combined with additional ES led to greater improvement in upper extremity motor function after stroke. The change in FMA scores was significantly higher in the experimental group compared to the control group.
Article
Clinical Neurology
Masahito Mihara, Hiroaki Fujimoto, Noriaki Hattori, Hironori Otomune, Yuta Kajiyama, Kuni Konaka, Yoshiyuki Watanabe, Yuichi Hiramatsu, Yoshihide Sunada, Ichiro Miyai, Hideki Mochizuki
Summary: SMA facilitation using fNIRS neurofeedback may improve poststroke gait and balance recovery.
Review
Medicine, General & Internal
Michal Starosta, Natalia Cichon, Joanna Saluk-Bijak, Elzbieta Miller
Summary: This review examines the current evidence of the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in post-stroke rehabilitation and discusses the effects of different stimulation types on motor function, cognitive function, depression, and aphasia. The findings suggest that rTMS is safe and can modulate cortical excitability to improve overall performance. However, the methodological problem of conducting double-blinding studies in stroke rehabilitation research is highlighted.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Clinical Neurology
Nan Chen, Xiao Qiu, Yan Hua, Jian Hu, Yulong Bai
Summary: This study aimed to observe the efficacy and explore the possible neurophysiological mechanism of applying sequential inhibitory and facilitatory rTMS for upper limb motor dysfunction post-stroke. The results showed that this therapy significantly promoted motor recovery in the patient, possibly by enhancing excitability in the ipsilesional hemisphere, restoring interhemispheric balance, and inducing cortical reorganization through neuroplasticity.
FRONTIERS IN NEUROLOGY
(2023)
Review
Neurosciences
Gengbin Chen, Manfeng Wu, Tuo Lin, Guiyuan Cai, Jiayue Xu, Qian Ding, Wanqi Li, Cheng Wu, Hongying Chen, Yue Lan
Summary: This systematic review and meta-analysis examined the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in helping chronic stroke patients recover from sequelae. The results showed that rTMS significantly improved upper limb function, hand function, and muscle tone. However, caution should be taken due to the small sample size of the meta-analysis.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Medicine, General & Internal
Yu-Chi Su, Yao-Hong Guo, Pei-Chun Hsieh, Yu-Ching Lin
Summary: The study suggests that repetitive transcranial magnetic stimulation (rTMS) is safe and effective in managing fibromyalgia-related symptoms, especially showing stronger effects in older patients. Reductions in pain, depression, and anxiety persisted for at least two weeks post-treatment, while effects on pain and depression remained significant up to one and a half months.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Immunology
Rongjun Sheng, Changchun Chen, Huan Chen, Peipei Yu
Summary: Stroke is a major cause of death and disability globally, and survivors often experience various dysfunctions. Repetitive transcranial magnetic stimulation (rTMS), as a noninvasive brain stimulation technique, has been shown to have positive effects on the recovery of motor, sensory, and cognitive functions in stroke patients.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Neurosciences
Tetsuo Koyama, Kohei Marumoto, Yuki Uchiyama, Hiroji Miyake, Kazuhisa Domen
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2015)
Article
Neurosciences
Ayano Nagano, Yoshitaka Yamada, Hiroji Miyake, Kazuhisa Domen, Tetsuo Koyama
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2016)
Article
Neurosciences
Ayano Nagano, Yoshitaka Yamada, Hiroji Miyake, Kazuhisa Domen, Tetsuo Koyama
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2016)
Article
Neurosciences
Koichi Hosomi, Shayne Morris, Tomosaburo Sakamoto, Junji Taguchi, Tomoyuki Maruo, Yu Kageyama, Yusuke Kinoshita, Yuko Goto, Toshio Shimokawa, Tetsuo Koyama, Youichi Saitoh
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2016)
Article
Neurosciences
Tetsuo Koyama, Kazuhisa Domen
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2017)
Article
Neurosciences
Tetsuo Koyama, Kazuhisa Domen
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2017)
Article
Neurosciences
Tetsuo Koyama, Masatoshi Koumo, Yuki Uchiyama, Kazuhisa Domen
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2018)
Article
Neurosciences
Yuki Uchiyama, Tetsuo Koyama, Yosuke Wada, Masashi Katsutani, Norihiko Kodama, Kazuhisa Domen
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2018)
Article
Neurosciences
Tetsuo Koyama, Masatoshi Koumo, Yuki Uchiyama, Kazuhisa Domen
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2018)
Article
Neurosciences
Yuki Uchiyama, Tetsuo Koyama, Yosuke Wada, Masashi Katsutani, Norihiko Kodama, Kazuhisa Domen
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2018)
Article
Neurosciences
Tetsuo Koyama, Yuki Uchiyama, Kazuhisa Domen
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2018)
Article
Neurosciences
Tetsuo Koyama, Yuki Uchiyama, Kazuhisa Domen
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2019)
Article
Rehabilitation
Kensaku Uchida, Yuki Uchiyama, Kazuhisa Domen, Tetsuo Koyama
Summary: The study developed a new predictive model by combining independence in eating and bladder management functions, and found that this three-level model is useful for predicting treatment outcomes of patients with ischemic stroke in acute care.
ANNALS OF REHABILITATION MEDICINE-ARM
(2021)
Article
Rehabilitation
Jun Saito, Tetsuo Koyama, Kazuhisa Domen
ANNALS OF REHABILITATION MEDICINE-ARM
(2018)
Article
Neurosciences
Adam Vacek, Grant Mair, Philip White, Philip M. Bath, Keith W. Muir, Rustam Al-Shahi Salman, Chloe Martin, David Dye, Francesca M. Chappell, Ruediger von Kummer, Malcolm Macleod, Nikola Sprigg, Joanna M. Wardlaw
Summary: This study evaluated the performance of e-ASPECTS software in delineating the extent of intracranial hemorrhage (ICH) on brain CT scans. The results showed that the software achieved excellent or good delineation of ICH extent in 71% of cases. However, it was more likely to over- or under-estimate the extent when ICH was more extensive, intraventricular, or extra-axial.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Mathias Jacobsen Bach, Audrone Jakubauskaite, Ian Law, Otto Molby Henriksen, Inger Havsteen, Alexander Cuculiza Henriksen, Sverre Rosenbaum, Lisbeth Marner
Summary: This study found that the rCBFacz value after ACZ challenge can serve as an important indicator for predicting future cerebrovascular events, with high accuracy and prognostic value.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Tak Kyu Oh, Saeyeon Kim, In-Ae Song
Summary: The study found that many survivors of nontraumatic intracranial hemorrhage in South Korea experience unemployment, decreased household income, and newly acquired disability after intensive care unit admission. However, these changes are not associated with 2-year all-cause mortality.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Eduardo Sousa de Melo, Rodrigo de Paiva Bezerra, Arthur Cesario de Holanda, Maria Junia Lira e Silva, Paloma Peter Travassos, Tayne Fernanda Lemos da Silva, Genova Maria de Azevedo Oliveira, Silvia Marinho Martins Alves, Carolina de Araujo Medeiros, Maria das Neves Dantas da Silveira Barros, Wilson Alves de Oliveira, Gisele Sampaio Silva, Luciana Patrizia Alves de Andrade Valenca
Summary: Cardiac involvement has been found to be the predominant factor correlated with stroke in Chagas disease. While atherosclerosis-related risk factors are prevalent, their influence on ischemic stroke in Chagas disease appears limited.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Pingping Zheng, Ning Zhang, Zixi Chen
Summary: This case presents a rare infectious cause of stroke and air embolism involving a pulmonary abscess and pulmonary vein thrombosis. Early detection, diagnosis, and appropriate treatment of infected systemic embolism in young patients are crucial to prevent serious complications.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Filippo Luca Gurgoglione, Luigi Vignali, Maria Alberta Cattabiani, Emilia Solinas, Giorgio Benatti, Iacopo Tadonio, Federico Barocelli, Chiara Dizdari, Domenico Tuttolomondo, Diego Ardissino, Francesco Nicolini, Giampaolo Niccoli
Summary: The incidence of recurrent ischemic neurological events after transcatheter patent foramen ovale closure is relatively low. Obesity, Risk of Paradoxical Embolism score < 7, and migraine are independent positive predictors of recurrent stroke or transient ischemic attack.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Angelo Cascio Rizzo, Ghil Schwarz, Amedeo Cervo, Giuditta Giussani, Chiara Ceresa, Antonella Gatti, Fausto De Angeli, Cristina Motto, Angelo Guccione, Rachele Tortorella, Giuseppe Granata, Claudia Rollo, Antonio Macera, Mariangela Piano, Guglielmo Pero, Elio Clemente Agostoni
Summary: This study aimed to evaluate the efficacy and safety of endovascular treatment (EVT) in primary and EVT-induced secondary medium-vessel occlusions (MeVO). The results showed that primary MeVO had poorer outcomes in terms of complications, EVT efficacy, and the proportion of patients with a modified Rankin Scale (mRS) of 0-2 at 3 months compared to exclusive large-vessel occlusion (LVO). However, EVT-induced secondary MeVO showed similar safety and efficacy outcomes as exclusive LVO and had better outcomes in terms of mRS 0-2 compared to primary MeVO.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jing Zhang, Chenming Wei, Jian Wu
Summary: This case report describes a patient with Bloom syndrome who developed acute cerebral infarction along with elevated antiphospholipid antibodies, suggesting a possible association between immune and coagulation abnormalities caused by Bloom syndrome and the development of acute cerebral infarction.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Yunxia Zhou, Shenglan He, Yanhong Hu
Summary: Compared with clopidogrel, DAPT with ticagrelor plus aspirin was associated with significantly lower thromboembolic events without an increase in hemorrhagic events in the treatment of intracranial aneurysms, according to the one-year clinical outcome analysis. However, larger upcoming trials are needed to confirm the effectiveness and safety of ticagrelor-associated DAPT.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Edvania Andrade de Moura Silva, Ludmilla Ribeiro Batista, Marcela Aline Fernandes Braga, Luci Fuscaldi Teixeira-Salmela, Christina Danielli Coelho de Morais Faria, Iza Faria-Fortini
Summary: The study found that stroke severity is the best predictor of self-perceived manual ability at both three and six months after stroke. Age, although significant, contributes little to the prediction of manual ability.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Sidarrth Prasad, Erica M. Jones, Mehari Gebreyohanns, Veronica Aguilera, DaiWai M. Olson, Jane A. Anderson, Sean I. Savitz, Salvador C. Flores, Steven J. Warach, Charlotte E. Rhodes, Mark P. Goldberg, Nneka L. Ifejika
Summary: This study identified the barriers and facilitators to adopting tenecteplase (TNK) as a thrombolytic treatment for acute ischemic stroke (AIS) by conducting qualitative research with stroke clinicians in Texas. The findings suggest that providing evidence and identifying key change processes can help clinicians achieve consensus on adopting TNK for AIS treatment.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jeshma Jayan, Sunil K. Narayan, Yasmin Nesha Haniffa, Navin Kumar
Summary: This study investigated the effects of transcranial electrical and magnetic stimulation on somatosensory evoked potentials in chronic ischemic stroke patients, finding that the real tDCS and rTMS combination results in significant improvement and is safe for use.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Phoebe M. Tran, Cenjing Zhu, William T. Harris II, Sajeesh K. Kamala Raghavan, Agricola Odoi, Liem Tran
Summary: This study assessed the geographic accessibility of stroke rehabilitation facilities in Tennessee. The study found that rural counties had significantly longer travel distances and times compared to urban counties. Counties with high and medium stroke prevalence also had higher travel times and distances compared to low stroke prevalence counties. Therefore, addressing transportation barriers and implementing tele-rehabilitation are crucial for improving access to stroke aftercare in these areas.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Lili Xu, Shuaiyu Chen, Jing Xu, Yanyan Shi, Zhihang Huang, Meng Wang, Ziqiao Wei, Hui Cao, Junshan Zhou, Wei Wang, Mingyang Du
Summary: This study found that the Chinese Visceral Adiposity Index (CVAI) is positively correlated with 90-day poor outcome in Chinese ischemic stroke patients after endovascular thrombectomy (EVT).
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Guangying Wu, Shuhua Li, Min Luo, Xiaotian Li, Xinghua Zhu, Junhuai Zhang, Qian He, Qian Yang, Guojiang Zhao, Shasha Luo, Zhijie Yang
Summary: The study aimed to investigate the relationship between serum alkaline phosphatase (ALP) levels and the severity and prognosis of intracerebral hemorrhage (ICH). The results showed that serum ALP levels in ICH patients were significantly elevated and correlated with hematoma volume and Glasgow coma scale (GCS) score. High serum ALP levels may serve as a potential predictor for the severity and unfavorable prognosis of ICH.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)