Article
Medicine, General & Internal
Federico Mazzacane, Valentina Mazzoleni, Elisa Scola, Sara Mancini, Ivano Lombardo, Giorgio Busto, Elisa Rognone, Anna Pichiecchio, Alessandro Padovani, Andrea Morotti, Enrico Fainardi
Summary: Cerebrovascular diseases are a leading cause of disability and death worldwide. Vessel wall magnetic resonance imaging (VW-MRI) can directly visualize intracranial arteries walls and their pathological alterations, providing important value in etiology, differential diagnosis, and risk assessment.
Article
Clinical Neurology
H. Kang, J. Liang, Y. Zhang, Z. Li, X. Yang, B. Sui
Summary: In this study, it was found that middle-aged and elderly patients with MCA stenosis were more likely to have hypertension and diabetes. Young patients tended to have longer lesions and more circular wall involvement and circular enhancement compared with the middle-aged and elderly group.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2021)
Article
Clinical Neurology
Mingming Lu, Hongtao Zhang, Shitong Liu, Dongqing Liu, Peng Peng, Fangbin Hao, Fei Yuan, Yuan Liu, Fugeng Sheng, Lichen Zhang, Xihai Zhao, Yao He, Cong Han, Jianming Cai
Summary: This study compared the long-term outcomes and surgical benefits between moyamoya disease (MMD) and atherosclerosis-associated moyamoya vasculopathy (AS-MMV) using high-resolution MRI (HRMRI). The findings showed that patients treated with encephaloduroarteriosynangiosis (EDAS) had a lower incidence of events, and MMD patients were more prone to ischemic stroke compared to AS-MMV patients. Therefore, HRMRI could be used to identify patients at a higher risk of future cerebrovascular events.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Review
Clinical Neurology
Yu Sakai, Vance T. Lehman, Laura B. Eisenmenger, Emmanuel C. Obusez, G. Abbas Kharal, Jiayu Xiao, Grace J. Wang, Zhaoyang Fan, Brett L. Cucchiara, Jae W. Song
Summary: Despite advancements in multi-modal imaging techniques, a significant portion of ischemic stroke patients remain undiagnosed. Vessel wall MRI (VW-MRI) has emerged as a promising tool for identifying culprit plaques and potential biomarkers in key anatomical areas. This review summarizes the existing evidence on the advantages of utilizing VW-MRI in ischemic stroke patients, particularly in identifying vulnerable plaques in the cervical carotid arteries, intracranial arteries, and the aortic arch. Future research directions and emerging techniques are also discussed.
FRONTIERS IN NEUROLOGY
(2022)
Article
Neurosciences
Lei Zhang, Yanjie Zhu, Yulong Qi, Liwen Wan, Lijie Ren, Yi Zhu, Na Zhang, Dong Liang, Ye Li, Hairong Zheng, Xin Liu
Summary: The study proposed a T-2-prepared sequence for whole-brain intracranial vessel wall imaging with cerebrospinal fluid (CSF) suppression. Evaluation on healthy volunteers and stroke patients suggested that T2IR-SPACE is a potential alternative T-2-weighted sequence for assessing intracranial vascular diseases.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Fang Wu, Miao Zhang, Zhigang Qi, Qingfeng Ma, Zhipeng Yu, Jie Lu
Summary: The purpose of this study was to use vessel wall magnetic resonance imaging (VW-MRI) to clarify vessel wall changes in vertebrobasilar dolichoectasia (VBD) associated with ischemic stroke. By comparing the vessel wall features between VBD patients with stroke and without stroke, it was found that the frequency of plaques was higher in VBD patients with stroke. Additionally, VBD patients with stroke had lower degree of stenosis, normalized wall index (NWI), and remodeling index (RI) compared to non-VBD stroke patients. These findings suggest that atherosclerosis may be an important cause of stroke in VBD patients.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Article
Multidisciplinary Sciences
Kang-Li Zhu, Zi-Yang Shang, Bai-jun Liu, Ying Wang, Jing Li, Ben-Qiang Yang, George Ntaios, Hui-Sheng Chen
Summary: This study aimed to investigate the association between intracranial non-stenotic atherosclerotic plaque and cerebral small vessel disease (CSVD) imaging markers, validated in embolic stroke of undetermined source (ESUS) patients. The results showed that intracranial non-stenotic atherosclerotic plaque, especially complicated plaque, was closely associated with CSVD imaging markers such as white matter hyperintensity, lacunes, and enlarged perivascular space.
SCIENTIFIC REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Dongye Li, Huiyu Qiao, Xieqing Yang, Jin Li, Wei Dai, Xiaoyi Chen, Jun Shen, Xihai Zhao
Summary: Co-existing hypertension and hyperhomocysteinemia (H-Hcy) are associated with carotid vulnerable plaque features, and the combination of the two has a stronger predictive value for subsequent vascular events than each measurement alone.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Neurosciences
Laura B. Eisenmenger, Jacqueline C. Junn, Daniel Cooke, Steven Hetts, Chengcheng Zhu, Kevin M. Johnson, Jesse M. Manunga, David Saloner, Christopher Hess, Helen Kim
Summary: High-resolution vessel wall MRI can help identify high-risk features in arteriovenous malformations (AVMs). This pilot study found vessel wall enhancement in most cases of clinically unruptured AVMs, suggesting the need for further investigation into the implications of these findings.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Konstanze Guggenberger, Axel J. Krafft, Ute Ludwig, Esther Raithel, Christoph Forman, Stephan Meckel, Juergen Hennig, Thorsten A. Bley, Patrick Vogel
Summary: An optimal framework for intracranial vessel wall imaging was demonstrated, utilizing a specially designed post-processing tool and a CS-accelerated MRI sequence to achieve high-resolution 3D black-blood data in under 10 minutes, allowing for the visualization of tortuous vessel structures. This approach enables simplified and optimized assessment of intracranial arteries in vascular disorders, particularly suspected vasculitis, with a processing time of approximately 15-20 minutes per patient, making it suitable for integration into clinical routine.
MAGNETIC RESONANCE IMAGING
(2021)
Review
Rheumatology
Serdar Arslan, Bora Korkmazer, Osman Kizilkilic
Summary: Vessel wall imaging (VWI) is a valuable noninvasive imaging method for distinguishing various intracranial vascular diseases by directly visualizing the vessel wall, especially in the differentiation of vasculitis, atherosclerosis, and dissection.
CURRENT OPINION IN RHEUMATOLOGY
(2021)
Article
Neurosciences
Jiayu Xiao, Matthew M. Padrick, Shlee S. Song, Zhaoyang Fan, Konrad H. Schlick
Summary: Intracranial atherosclerotic disease (ICAD) is a dynamic process leading to ischemic stroke, and symptomatic patients may have a high recurrent rate even with standard treatment. Serial MR imaging can help to understand the response of patients to medication, and early identification of poor responders is crucial in preventing recurrence of cardiovascular events in ICAD patients.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yasutaka Fushimi, Kazumichi Yoshida, Masakazu Okawa, Takakuni Maki, Satoshi Nakajima, Akihiko Sakata, Sachi Okuchi, Takuya Hinoda, Mitsunori Kanagaki, Yuji Nakamoto
Summary: Vessel wall MR imaging (VW-MRI) has been widely used in clinical practice for the diagnosis and evaluation of arterial diseases, venous diseases, vasculitis, and leptomeningeal diseases.
Article
Radiology, Nuclear Medicine & Medical Imaging
Weiwei Xie, Chen Wang, Song Liu, Ruowei Tang, Shengting Chai, Yu Guo, Tianyi Qian, Binge Chang, Qi Yang, Zhaoyang Fan, Shuang Xia
Summary: There is a close relationship between LSAs and LIs in the basal ganglia, with the number and length of LSAs being statistically different in basal ganglias with and without LIs. The total number of LSAs and ipsilateral MCA-M1 plaques were independently related to LIs, and the mean length of LSAs was negatively correlated with the number and volume of LIs. Age, drinking history, and mean length of LSAs were associated with LI occurrence in the basal ganglia, with shorter LSAs correlated with larger volume of LIs.
EUROPEAN RADIOLOGY
(2021)
Article
Clinical Neurology
Neha Choudhary, Sameer Vyas, Manish Modi, Shashank Raj, Ajay Kumar, Naveen Sankhyan, Renu Suthar, Arushi Gahlot Saini, Manoj Kumar Goyal, Chirag Kamal Ahuja, Paramjeet Singh
Summary: Tubercular vasculitis can be detected by VWI in the form of nodular or smooth segmental enhancement of vessel wall with or without stenosis. Incorporation of VWI in routine MR imaging can play a greater role in early detection and management of cerebrovascular complications which can help to improve prognosis of the disease.
Article
Clinical Neurology
S. Narumi, M. Sasaki, T. Natori, M. Yamaguchi Oura, K. Ogasawara, M. Kobayashi, Y. Sato, Y. Ogasawara, J. Hitomi, Y. Terayama
AMERICAN JOURNAL OF NEURORADIOLOGY
(2015)
Article
Clinical Neurology
Y. Sato, K. Ogasawara, S. Narumi, M. Sasaki, A. Saito, E. Tsushima, T. Namba, M. Kobayashi, K. Yoshida, Y. Terayama, A. Ogawa
AMERICAN JOURNAL OF NEURORADIOLOGY
(2016)
Article
Neurosciences
Tatsunori Natori, Makoto Sasaki, Mitsuharu Miyoshi, Kohei Ito, Hideki Ohba, Haruna Miyazawa, Shinsuke Narumi, Hiroyuki Kabasawa, Taisuke Harada, Yasuo Terayama
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2016)
Article
Neurosciences
Shinsuke Narumi, Makoto Sasaki, Haruna Miyazawa, Tatsunori Natori, Kohei Ito, Kuniaki Ogasawara, Masakazu Kobayashi, Jiro Hitomi, Yasuo Terayama
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2017)
Article
Neurosciences
Shinsuke Narumi, Makoto Sasaki, Haruna Miyazawa, Tatsunori Natori, Kohei Ito, Kuniaki Ogasawara, Masakazu Kobayashi, Jiro Hitomi, Yasuo Terayama
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2017)
Article
Clinical Neurology
S. Narumi, M. Sasaki, H. Ohba, K. Ogasawara, M. Kobayashi, J. Hitomi, K. Mori, K. Ohura, M. Yamaguchi, K. Kudo, Y. Terayama
AMERICAN JOURNAL OF NEURORADIOLOGY
(2013)
Article
Clinical Neurology
S. Narumi, M. Sasaki, H. Ohba, K. Ogasawara, M. Kobayashi, T. Natori, J. Hitomi, H. Itagaki, T. Takahashi, Y. Terayama
AMERICAN JOURNAL OF NEURORADIOLOGY
(2014)
Article
Clinical Neurology
Takaaki Beppu, Shunrou Fujiwara, Hideaki Nishimoto, Atsuhiko Koeda, Shinsuke Narumi, Kiyoshi Mori, Kuniaki Ogasawara, Makoto Sasaki
JOURNAL OF NEUROLOGY
(2012)
Article
Neurosciences
Mao Yamaguchi Oura, Makoto Sasaki, Hideki Ohba, Shinsuke Narumi, Kazumasa Oura, Ikuko Uwano, Yasuo Terayama
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2014)
Article
Neurosciences
Tatsunori Natori, Makoto Sasaki, Mitsuharu Miyoshi, Hideki Ohba, Mao Yamaguchi Oura, Shinsuke Narumi, Taisuke Harada, Hiroyuki Kabasawa, Yasuo Terayama
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2014)
Article
Neurosciences
Tatsunori Natori, Makoto Sasaki, Mitsuharu Miyoshi, Hideki Ohba, Noriyuki Katsura, Mao Yamaguchi, Shinsuke Narumi, Hiroyuki Kabasawa, Kohsuke Kudo, Kenji Ito, Yasuo Terayama
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2014)
Article
Cardiac & Cardiovascular Systems
Kohki Oikawa, Tadayoshi Kato, Kazumasa Oura, Shinsuke Narumi, Makoto Sasaki, Shunrou Fujiwara, Masakazu Kobayashi, Yoshiyasu Matsumoto, Jun-ichi Nomura, Kenji Yoshida, Yasuo Terayama, Kuniaki Ogasawara
Article
Biochemistry & Molecular Biology
Yasushi Ogasawara, Yuiko Sato, Shinsuke Narumi, Makoto Sasaki, Shunrou Fujiwara, Masakazu Kobayashi, Kenji Yoshida, Yasuo Terayama, Kuniaki Ogasawara
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2016)
Article
Clinical Neurology
Shinsuke Narumi, Tatsunori Natori, Haruna Miyazawa, Tadayoshi Kato, Hisashi Yonezawa, Ichizo Nishino, Masayuki Nakamura, Akira Sano, Yasuo Terayama
NEUROLOGY AND CLINICAL NEUROSCIENCE
(2016)
Article
Neurosciences
Adam Vacek, Grant Mair, Philip White, Philip M. Bath, Keith W. Muir, Rustam Al-Shahi Salman, Chloe Martin, David Dye, Francesca M. Chappell, Ruediger von Kummer, Malcolm Macleod, Nikola Sprigg, Joanna M. Wardlaw
Summary: This study evaluated the performance of e-ASPECTS software in delineating the extent of intracranial hemorrhage (ICH) on brain CT scans. The results showed that the software achieved excellent or good delineation of ICH extent in 71% of cases. However, it was more likely to over- or under-estimate the extent when ICH was more extensive, intraventricular, or extra-axial.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Mathias Jacobsen Bach, Audrone Jakubauskaite, Ian Law, Otto Molby Henriksen, Inger Havsteen, Alexander Cuculiza Henriksen, Sverre Rosenbaum, Lisbeth Marner
Summary: This study found that the rCBFacz value after ACZ challenge can serve as an important indicator for predicting future cerebrovascular events, with high accuracy and prognostic value.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Tak Kyu Oh, Saeyeon Kim, In-Ae Song
Summary: The study found that many survivors of nontraumatic intracranial hemorrhage in South Korea experience unemployment, decreased household income, and newly acquired disability after intensive care unit admission. However, these changes are not associated with 2-year all-cause mortality.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Eduardo Sousa de Melo, Rodrigo de Paiva Bezerra, Arthur Cesario de Holanda, Maria Junia Lira e Silva, Paloma Peter Travassos, Tayne Fernanda Lemos da Silva, Genova Maria de Azevedo Oliveira, Silvia Marinho Martins Alves, Carolina de Araujo Medeiros, Maria das Neves Dantas da Silveira Barros, Wilson Alves de Oliveira, Gisele Sampaio Silva, Luciana Patrizia Alves de Andrade Valenca
Summary: Cardiac involvement has been found to be the predominant factor correlated with stroke in Chagas disease. While atherosclerosis-related risk factors are prevalent, their influence on ischemic stroke in Chagas disease appears limited.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Pingping Zheng, Ning Zhang, Zixi Chen
Summary: This case presents a rare infectious cause of stroke and air embolism involving a pulmonary abscess and pulmonary vein thrombosis. Early detection, diagnosis, and appropriate treatment of infected systemic embolism in young patients are crucial to prevent serious complications.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Filippo Luca Gurgoglione, Luigi Vignali, Maria Alberta Cattabiani, Emilia Solinas, Giorgio Benatti, Iacopo Tadonio, Federico Barocelli, Chiara Dizdari, Domenico Tuttolomondo, Diego Ardissino, Francesco Nicolini, Giampaolo Niccoli
Summary: The incidence of recurrent ischemic neurological events after transcatheter patent foramen ovale closure is relatively low. Obesity, Risk of Paradoxical Embolism score < 7, and migraine are independent positive predictors of recurrent stroke or transient ischemic attack.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Angelo Cascio Rizzo, Ghil Schwarz, Amedeo Cervo, Giuditta Giussani, Chiara Ceresa, Antonella Gatti, Fausto De Angeli, Cristina Motto, Angelo Guccione, Rachele Tortorella, Giuseppe Granata, Claudia Rollo, Antonio Macera, Mariangela Piano, Guglielmo Pero, Elio Clemente Agostoni
Summary: This study aimed to evaluate the efficacy and safety of endovascular treatment (EVT) in primary and EVT-induced secondary medium-vessel occlusions (MeVO). The results showed that primary MeVO had poorer outcomes in terms of complications, EVT efficacy, and the proportion of patients with a modified Rankin Scale (mRS) of 0-2 at 3 months compared to exclusive large-vessel occlusion (LVO). However, EVT-induced secondary MeVO showed similar safety and efficacy outcomes as exclusive LVO and had better outcomes in terms of mRS 0-2 compared to primary MeVO.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jing Zhang, Chenming Wei, Jian Wu
Summary: This case report describes a patient with Bloom syndrome who developed acute cerebral infarction along with elevated antiphospholipid antibodies, suggesting a possible association between immune and coagulation abnormalities caused by Bloom syndrome and the development of acute cerebral infarction.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Yunxia Zhou, Shenglan He, Yanhong Hu
Summary: Compared with clopidogrel, DAPT with ticagrelor plus aspirin was associated with significantly lower thromboembolic events without an increase in hemorrhagic events in the treatment of intracranial aneurysms, according to the one-year clinical outcome analysis. However, larger upcoming trials are needed to confirm the effectiveness and safety of ticagrelor-associated DAPT.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Edvania Andrade de Moura Silva, Ludmilla Ribeiro Batista, Marcela Aline Fernandes Braga, Luci Fuscaldi Teixeira-Salmela, Christina Danielli Coelho de Morais Faria, Iza Faria-Fortini
Summary: The study found that stroke severity is the best predictor of self-perceived manual ability at both three and six months after stroke. Age, although significant, contributes little to the prediction of manual ability.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Sidarrth Prasad, Erica M. Jones, Mehari Gebreyohanns, Veronica Aguilera, DaiWai M. Olson, Jane A. Anderson, Sean I. Savitz, Salvador C. Flores, Steven J. Warach, Charlotte E. Rhodes, Mark P. Goldberg, Nneka L. Ifejika
Summary: This study identified the barriers and facilitators to adopting tenecteplase (TNK) as a thrombolytic treatment for acute ischemic stroke (AIS) by conducting qualitative research with stroke clinicians in Texas. The findings suggest that providing evidence and identifying key change processes can help clinicians achieve consensus on adopting TNK for AIS treatment.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jeshma Jayan, Sunil K. Narayan, Yasmin Nesha Haniffa, Navin Kumar
Summary: This study investigated the effects of transcranial electrical and magnetic stimulation on somatosensory evoked potentials in chronic ischemic stroke patients, finding that the real tDCS and rTMS combination results in significant improvement and is safe for use.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Phoebe M. Tran, Cenjing Zhu, William T. Harris II, Sajeesh K. Kamala Raghavan, Agricola Odoi, Liem Tran
Summary: This study assessed the geographic accessibility of stroke rehabilitation facilities in Tennessee. The study found that rural counties had significantly longer travel distances and times compared to urban counties. Counties with high and medium stroke prevalence also had higher travel times and distances compared to low stroke prevalence counties. Therefore, addressing transportation barriers and implementing tele-rehabilitation are crucial for improving access to stroke aftercare in these areas.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Lili Xu, Shuaiyu Chen, Jing Xu, Yanyan Shi, Zhihang Huang, Meng Wang, Ziqiao Wei, Hui Cao, Junshan Zhou, Wei Wang, Mingyang Du
Summary: This study found that the Chinese Visceral Adiposity Index (CVAI) is positively correlated with 90-day poor outcome in Chinese ischemic stroke patients after endovascular thrombectomy (EVT).
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Guangying Wu, Shuhua Li, Min Luo, Xiaotian Li, Xinghua Zhu, Junhuai Zhang, Qian He, Qian Yang, Guojiang Zhao, Shasha Luo, Zhijie Yang
Summary: The study aimed to investigate the relationship between serum alkaline phosphatase (ALP) levels and the severity and prognosis of intracerebral hemorrhage (ICH). The results showed that serum ALP levels in ICH patients were significantly elevated and correlated with hematoma volume and Glasgow coma scale (GCS) score. High serum ALP levels may serve as a potential predictor for the severity and unfavorable prognosis of ICH.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)