The role of nuclear receptors in regulation of Th17/Treg biology and its implications for diseases
出版年份 2015 全文链接
标题
The role of nuclear receptors in regulation of Th17/Treg biology and its implications for diseases
作者
关键词
-
出版物
Cellular & Molecular Immunology
Volume 12, Issue 5, Pages 533-542
出版商
Springer Nature
发表日期
2015-09-07
DOI
10.1038/cmi.2015.21
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Th17 cells in autoimmune diseases
- (2015) Lei Han et al. Frontiers of Medicine
- The Evidence for a Beneficial Role of Vitamin A in Multiple Sclerosis
- (2014) Yara Dadalti Fragoso et al. CNS DRUGS
- Retinoic Acid Increases Foxp3+ Regulatory T Cells and Inhibits Development of Th17 Cells by Enhancing TGF- -Driven Smad3 Signaling and Inhibiting IL-6 and IL-23 Receptor Expression
- (2014) S. Xiao et al. JOURNAL OF IMMUNOLOGY
- Vitamin D as a novel therapy in inflammatory bowel disease: new hope or false dawn?
- (2014) Maria O'Sullivan PROCEEDINGS OF THE NUTRITION SOCIETY
- Phenotype and functions of memory Tfh cells in human blood
- (2014) Nathalie Schmitt et al. TRENDS IN IMMUNOLOGY
- The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3
- (2013) Zuojia Chen et al. IMMUNITY
- Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity
- (2013) Jorg van Loosdregt et al. IMMUNITY
- Metabolic control of the Treg/Th17 axis
- (2013) Joseph Barbi et al. IMMUNOLOGICAL REVIEWS
- Retinoid X Receptor Agonists Modulate Foxp3+ Regulatory T Cell and Th17 Cell Differentiation with Differential Dependence on Retinoic Acid Receptor Activation
- (2013) H. Takeuchi et al. JOURNAL OF IMMUNOLOGY
- Biased Treg/Th17 balance away from regulatory toward inflammatory phenotype in relapsed multiple sclerosis and its correlation with severity of symptoms
- (2013) Azam Jamshidian et al. JOURNAL OF NEUROIMMUNOLOGY
- Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis
- (2013) Takashi Sekiya et al. NATURE IMMUNOLOGY
- Liver X receptors: Emerging therapeutic targets for Alzheimer's disease
- (2013) Rupinder K. Sodhi et al. PHARMACOLOGICAL RESEARCH
- Nuclear Receptor NR4A2 Orchestrates Th17 Cell-Mediated Autoimmune Inflammation via IL-21 Signalling
- (2013) Ben J. E. Raveney et al. PLoS One
- Dramatic Survival Benefit Related to R0 Resection of Pancreatic Adenocarcinoma in Patients With Tumor ≤25 mm in Size and ≤1 Involved Lymph Nodes
- (2013) Pavan Tummala et al. Clinical and Translational Gastroenterology
- 1,25-Dihyroxyvitamin D3 Promotes FOXP3 Expression via Binding to Vitamin D Response Elements in Its Conserved Noncoding Sequence Region
- (2012) S. W. Kang et al. JOURNAL OF IMMUNOLOGY
- Metabolic checkpoints in activated T cells
- (2012) Ruoning Wang et al. NATURE IMMUNOLOGY
- Skin-Targeted Inhibition of PPAR β/δ by Selective Antagonists to Treat PPAR β/δ – Mediated Psoriasis-Like Skin Disease In Vivo
- (2012) Katrin Hack et al. PLoS One
- Peroxisome proliferator-activated receptor (PPAR) and - regulate IFN and IL-17A production by human T cells in a sex-specific way
- (2012) M. A. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion
- (2012) M. S. Fassett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regression of Inflammation in Atherosclerosis by the LXR Agonist R211945
- (2012) Esad Vucic et al. JACC-Cardiovascular Imaging
- Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
- (2011) Eric V. Dang et al. CELL
- Lack of IL-2 in PPAR-α-deficient mice triggers allergic contact dermatitis by affecting regulatory T cells
- (2011) Sandrine Dubrac et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Nuclear receptors: TH 17 cell control from within
- (2011) L. Klotz et al. FEBS LETTERS
- Regulatory T cells and Foxp3
- (2011) Alexander Y. Rudensky IMMUNOLOGICAL REVIEWS
- 1,25-Dihydroxyvitamin D3 inhibits proliferation but not the suppressive function of regulatory T cells in the absence of antigen-presenting cells
- (2011) Ai-Leng Khoo et al. IMMUNOLOGY
- Converging pathways lead to overproduction of IL-17 in the absence of vitamin D signaling
- (2011) Danny Bruce et al. INTERNATIONAL IMMUNOLOGY
- Nuclear receptors take center stage in Th17 cell–mediated autoimmunity
- (2011) Jennifer J. Heller et al. JOURNAL OF CLINICAL INVESTIGATION
- Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation
- (2011) Guoliang Cui et al. JOURNAL OF CLINICAL INVESTIGATION
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
- (2011) Jun R. Huh et al. NATURE
- Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand
- (2011) Laura A. Solt et al. NATURE
- Retinoic Acid and Rapamycin Differentially Affect and Synergistically Promote the Ex Vivo Expansion of Natural Human T Regulatory Cells
- (2011) Tatiana N. Golovina et al. PLoS One
- Estrogen-related receptor- is a metabolic regulator of effector T-cell activation and differentiation
- (2011) R. D. Michalek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells
- (2011) Takashi Sekiya et al. Nature Communications
- PPARδ deficient mice develop elevated Th1/Th17 responses and prolonged experimental autoimmune encephalomyelitis
- (2010) Saravanan Kanakasabai et al. BRAIN RESEARCH
- The Mammalian Target of Rapamycin: Linking T Cell Differentiation, Function, and Metabolism
- (2010) Jonathan D. Powell et al. IMMUNITY
- Peroxisome proliferator-activated receptor δ agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis
- (2010) Saravanan Kanakasabai et al. IMMUNOLOGY
- Thematic Minireview Series on Nuclear Receptors in Biology and Diseases
- (2010) Sohaib Khan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endogenous Ligands for Nuclear Receptors: Digging Deeper
- (2010) Michael Schupp et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peroxisome Proliferator-Activated Receptor and Agonists Together with TGF- Convert Human CD4+CD25- T Cells into Functional Foxp3+ Regulatory T Cells
- (2010) J. Lei et al. JOURNAL OF IMMUNOLOGY
- STAT1-Activating Cytokines Limit Th17 Responses through Both T-bet-Dependent and -Independent Mechanisms
- (2010) A. V. Villarino et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: All-Trans Retinoic Acid Sustains the Stability and Function of Natural Regulatory T Cells in an Inflammatory Milieu
- (2010) X. Zhou et al. JOURNAL OF IMMUNOLOGY
- Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell–like and Foxp3+ regulatory T cells
- (2010) Roopali Gandhi et al. NATURE IMMUNOLOGY
- Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism
- (2010) N. T. Nguyen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis
- (2010) F. J. Quintana et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Retinoic Acid Can Directly Promote TGF-β-Mediated Foxp3+ Treg Cell Conversion of Naive T Cells
- (2009) Daniel Mucida et al. IMMUNITY
- Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?
- (2009) Maria A. Curotto de Lafaille et al. IMMUNITY
- Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression
- (2009) Ethan M. Shevach IMMUNITY
- Liver X receptor in cholesterol metabolism
- (2009) Chunyan Zhao et al. JOURNAL OF ENDOCRINOLOGY
- Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines
- (2009) Jens Nolting et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity
- (2009) Luisa Klotz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulation of Th17 Differentiation by Epidermal Fatty Acid-Binding Protein
- (2009) B. Li et al. JOURNAL OF IMMUNOLOGY
- Transcriptional Modulation of the Immune Response by Peroxisome Proliferator-Activated Receptor- Agonists in Autoimmune Disease
- (2009) A. R. Gocke et al. JOURNAL OF IMMUNOLOGY
- All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis
- (2009) Aiping Bai et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Vitamin D Status Is Positively Correlated with Regulatory T Cell Function in Patients with Multiple Sclerosis
- (2009) Joost Smolders et al. PLoS One
- Interleukin-17–producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers
- (2008) Kiran Nistala et al. ARTHRITIS AND RHEUMATISM
- LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response
- (2008) Steven J. Bensinger et al. CELL
- Retinoic Acid Enhances Foxp3 Induction Indirectly by Relieving Inhibition from CD4+CD44hi Cells
- (2008) Jonathan A. Hill et al. IMMUNITY
- T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ
- (2008) Xuexian O. Yang et al. IMMUNITY
- Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs
- (2008) Xuexian O. Yang et al. IMMUNITY
- Foxp3 Inhibits RORγt-mediatedIL-17AmRNA Transcription through Direct Interaction with RORγt
- (2008) Kenji Ichiyama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells
- (2008) Marc Veldhoen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
- (2008) Marc Veldhoen et al. NATURE
- Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
- (2008) Francisco J. Quintana et al. NATURE
- TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
- (2008) Liang Zhou et al. NATURE
- IL-21 and TGF-β are required for differentiation of human TH17 cells
- (2008) Li Yang et al. NATURE
- Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells
- (2008) A. Kimura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Th17 cells
- (2008) Sergio Romagnani ARTHRITIS RESEARCH & THERAPY
- The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor
- (2007) Linh P. Nguyen et al. CHEMICAL RESEARCH IN TOXICOLOGY
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