Article
Respiratory System
Magnus Ekstrom, Ane Johannessen, Michael J. Abramson, Bryndis Benediktsdottir, Karl Franklin, Thorarinn Gislason, Francisco Gomez Real, Mathias Holm, Christer Janson, Rain Jogi, Adrian Lowe, Andrei Malinovschi, Jesus Martinez-Moratalla, Anna Oudin, Jose Luis Sanchez-Ramos, Vivi Schlunssen, Cecilie Svanes
Summary: The study found that parents with breathlessness were more likely to have children who also developed breathlessness, with independent risk factors including obesity, smoking, asthma, depression, lower lung function, and female sex.
Article
Respiratory System
Sarah L. Finnegan, Michael Browning, Eugene Duff, Catherine J. Harmer, Andrea Reinecke, Najib M. Rahman, Kyle T. S. Pattinson
Summary: Brain activity to breathlessness related cues is a strong predictor of clinical improvement in breathlessness over pulmonary rehabilitation.
Article
Respiratory System
Slavica Kochovska, David Currow, Sungwon Chang, Miriam Johnson, Diana Ferreira, Deidre Morgan, Max Olsson, Magnus Ekstrom
Summary: The study evaluates the impact of breathlessness on daily activity function in older men. It finds that worsening breathlessness is associated with decreased levels of physical activity, sexual activity, and overall function. This is also correlated with increased anxiety and depression.
BMJ OPEN RESPIRATORY RESEARCH
(2022)
Article
Respiratory System
Leanne M. Poulos, Rosario D. Ampon, David C. Currow, Guy B. Marks, Brett G. Toelle, Helen K. Reddel
Summary: Chronic respiratory symptoms such as breathlessness and cough can lead to significant distress and may indicate underlying health issues. A survey in Australia found that a high percentage of adults experience breathlessness, with many suffering from health burdens even without a diagnosed respiratory or heart condition. The extent of underdiagnosis of these conditions or alternative causes of breathlessness warrants further investigation.
Review
Psychology, Biological
Olivia K. Harrison, Lucy Marlow, Sarah L. Finnegan, Ben Ainsworth, Kyle T. S. Pattinson
Summary: The study found inter-relationships between interoception, mood, and attention in individuals with asthma, with negative mood correlating with decreased interoceptive ability and faster reaction times in an attention task. Clustering analysis identified two concordant asthma subgroups and one discordant subgroup based on symptoms, pathophysiology, and mood, suggesting that mood may play a role in interpreting bodily sensations in individuals with asthma.
BIOLOGICAL PSYCHOLOGY
(2021)
Article
Respiratory System
Sarah L. Finnegan, Olivia K. Harrison, Catherine J. Harmer, Mari Herigstad, Najib M. Rahman, Andrea Reinecke, Kyle T. S. Pattinson
Summary: This study focused on 91 participants with mild-to-moderate chronic obstructive pulmonary disease (COPD), utilizing unsupervised machine learning techniques to model brain-behavior-breathlessness links. The results successfully stratified participants into four key factors corresponding to mood, symptom burden, and capability measures, leading to the identification of high and low symptom burden groups with distinct brain activity patterns. This highlights the importance of multimodal models in understanding breathlessness burden and identifying behavioral phenotypes.
EUROPEAN RESPIRATORY JOURNAL
(2021)
Review
Medicine, General & Internal
Josephine L. Feliciano, Julie M. Waldfogel, Ritu Sharma, Allen Zhang, Arjun Gupta, Ramy Sedhom, Jeff Day, Eric B. Bass, Sydney M. Dy
Summary: This systematic review and meta-analysis included 19 studies evaluating pharmacologic interventions for breathlessness in patients with advanced cancer. The evidence did not support the association of opioids or other pharmacologic interventions with improved breathlessness. While pharmacologic interventions demonstrated some harms compared with usual care, dropout attributable to adverse events was minimal in these short-term studies.
Article
Respiratory System
Yue Leon Guo, Maria R. Ampon, Leanne M. Poulos, Sharon R. Davis, Brett G. Toelle, Guy B. Marks, Helen K. Reddel
Summary: This study estimated the contribution of obesity to breathlessness in Australian adults using the population attributable fraction (PAF). The results showed that obesity accounted for approximately a quarter of breathlessness symptoms and had a higher proportion in women.
Review
Cardiac & Cardiovascular Systems
Anthony Paulo Sunjaya, Agnivo Sengupta, Allison Martin, Gian Luca Di Tanna, Christine Jenkins
Summary: This systematic review evaluates the clinical efficacy of breathlessness apps and assesses the quality of publicly available apps. The results show that longer-term use of mobile apps can provide clinical benefits to patients. However, publicly available apps have low quality and lack in information quality and user engagement.
RESPIRATORY MEDICINE
(2022)
Article
Respiratory System
Sarah L. Finnegan, Kyle T. S. Pattinson, Josefin Sundh, Magnus Skold, Christer Janson, Anders Blomberg, Jacob Sandberg, Magnus Ekstrom
Summary: This study used data-driven techniques to identify and confirm four stable factors underlying the experience of breathlessness in patients with various cardiorespiratory diseases, labeled as body burden, affect/mood, breathing burden, and anger/frustration. Stratifying patients based on these factors revealed two groups corresponding to high and low burden, which remained stable after 6 months. This work supports disease-independent approaches to assess breathlessness.
Article
Public, Environmental & Occupational Health
Julie Spray, Jean Hunleth, Sienna Ruiz, Julia Maki, David A. Fedele, Sreekala Prabhakaran, Hannah Fechtel, James A. Shepperd, Deborah J. Bowen, Erika A. Waters
Summary: Caregivers' and children's conceptual models of asthma are influenced by embodiment theory, with the processes of symptom perception-detection and interpretation shaping their understanding. Symptoms are experienced in the context of other bodily processes, acute symptoms and exacerbations are more salient, and the experience of asthma involves integrated physiological and emotional processes.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Medicine, General & Internal
Shuyan Guo, Yin Wang, Hao Chen, Nan Huang, Wenjing Li, Dongxia Ma, Yaqi Yang, Shuchen Zhang, Rongfei Zhu
Summary: This study investigated the prevalence of respiratory allergies, parents' perceptions of them, and their unmet needs for information in a population of 3- to 16-year-old children. The results showed a high prevalence of respiratory allergies in this population, but parents had insufficient knowledge about the illness and asthma. Therefore, it is crucial to increase parents' awareness of respiratory allergies and facilitate their access to informative and professional platforms.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Construction & Building Technology
Juan Wang, Yinping Zhang, Baizhan Li, Zhuohui Zhao, Chen Huang, Xin Zhang, Qihong Deng, Chan Lu, Hua Qian, Xu Yang, Yuexia Sun, Dan Norba
Summary: A questionnaire survey was conducted in eight Chinese cities, involving 40,279 adults with a response rate of 75%. The survey focused on demographic information, allergic rhinitis, asthma, perceived odors, and home environment. The results showed that mold and dampness in dwellings were associated with adult allergic rhinitis, asthma, and odors. Different odors were related to allergic rhinitis and asthma. Odor perception partly mediated the effects of mold and dampness on allergic rhinitis and asthma, but most of the effects were direct.
BUILDING AND ENVIRONMENT
(2023)
Article
Respiratory System
Kris Mooren, Danielle Wester, Huib Kerstjens, Erik Bergkamp, Anna Spathis, Yvonne Engels
Summary: This study aimed to demonstrate the feasibility of setting up a breathlessness service specifically for COPD patients and evaluate its effectiveness and satisfaction. The results showed that providing a breathlessness service for COPD outpatients with refractory breathlessness is feasible and can significantly improve patients' CRQ scores. The service was also highly rated by both patients and health professionals.
COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2022)
Article
Health Care Sciences & Services
Audrey Fossati, Caroline Challier, Aman Allah Dalhoumi, Javier Rose, Annick Robinson, Caroline Perisson, Francois Galode, Baptiste Luaces, Michael Fayon
Summary: This study evaluated the ability of clinical and spirometric telemonitoring to characterize the perception profile of bronchial obstruction in asthmatic children and its impact on asthma management. The results showed that telemonitoring could assist in determining the perception profile and was well accepted by patients.
Letter
Critical Care Medicine
Justin L. Garner, Martyn F. Biddiscombe, Sally Meah, Adam Lewis, Sara C. Buttery, Nicholas S. Hopkinson, Samuel V. Kemp, Omar S. Usmani, Pallav L. Shah, Sylvia Verbanck
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Letter
Critical Care Medicine
Keir E. J. Philip, Adam Lewis, Sara C. Buttery, Colm McCabe, Daisy Fancourt, Christopher M. Orton, Michael I. Polkey, Nicholas S. Hopkinson
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Respiratory System
Matthew J. Pavitt, Adam Lewis, Sara C. Buttery, Bernadette O. Fernandez, Monika Mikus-Lelinska, Winston A. S. Banya, Martin Feelisch, Michael Polkey, Nicholas S. Hopkinson
Summary: The study found that acute dietary nitrate supplementation significantly improved exercise performance and endothelial function in COPD patients requiring supplemental oxygen.
Article
Respiratory System
Adam Lewis, Keir Elmslie James Philip, Adam Lound, Phoene Cave, Juliet Russell, Nicholas S. Hopkinson
Summary: Singing is a popular activity for COPD patients and may improve health measures and quality of life. The physiological mechanisms of singing for lung health require further evaluation to understand the potential benefits.
BMJ OPEN RESPIRATORY RESEARCH
(2021)
Article
Critical Care Medicine
Keir E. J. Philip, Harriet Owles, Stephanie McVey, Tanja Pagnuco, Katie Bruce, Harry Brunjes, Winston Banya, Jenny Mollica, Adam Lound, Suzi Zumpe, Amiad M. Abrahams, Vijay Padmanaban, Thomas H. Hardy, Adam Lewis, Ajit Lalvani, Sarah Elkin, Nicholas S. Hopkinson
Summary: This study found that participating in an online breathing and wellbeing program can improve the mental health component of health related quality-of-life and reduce breathlessness in individuals with persistent symptoms after COVID-19. Mind-body and music-based approaches may play a role in supporting recovery.
LANCET RESPIRATORY MEDICINE
(2022)
Editorial Material
Respiratory System
Adam Lewis, Christian Robert Osadnik
Article
Respiratory System
Adam Lewis, Elmar Kal, Claire Marie Nolan, Phoene Cave, Lizzie Grillo, Joy Conway, Mandy Jones
Summary: This study aims to compare the effects of physiotherapy-led and music therapy-led breathing exercises on individuals with breathing pattern disorder. Forty participants aged 18-40 years, scoring at least 19 on the Nijmegen Questionnaire and without any underlying respiratory conditions, will be recruited. Participants will be randomly assigned to receive either physiotherapy-led or music therapy-led breathing exercises for 6 weeks, and qualitative interviews will be conducted to understand their experiences.
BMJ OPEN RESPIRATORY RESEARCH
(2022)
Article
Respiratory System
Jennifer Steinmann, Adam Lewis, Toby J. Ellmers, Mandy Jones, Vicky MacBean, Elmar Kal
Summary: The Breathing Vigilance Questionnaire (Breathe-VQ) is a valid and reliable tool to measure breathing vigilance, which can determine the presence of dysfunctional breathing by examining its correlation with factors such as anxiety and autonomic dysfunction. High vigilance may contribute to breathing disorders and can be targeted in therapy.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Review
Respiratory System
Lizzie J. F. Grillo, Georgie M. Housley, Sidhu Gangadharan, Adnan Majid, James H. Hull
Summary: Large airway collapse (LAC) is an abnormal inward movement of the large airways during the expiratory phase, commonly seen in chronic respiratory conditions. It impairs airway clearance and causes breathlessness and exercise intolerance. This article provides physiotherapeutic intervention advice based on the understanding of LAC's pathophysiology, focusing on optimizing airways, breathing, and exercise capacity.
Article
Respiratory System
Adam Lewis, Joy Conway, Jack Middleton, Chris K. Startup, James Wyatt
Summary: This qualitative study investigated the experience of playing the harmonica for individuals with COPD. The study found that individuals initially struggle with playing the harmonica, but with practice and quality teaching, they are able to improve breathing control and find enjoyment and relaxation. Playing the harmonica not only offers a breathing control strategy, but also helps with mucous expectoration. Despite the loss of group interaction when participating online, the harmonica group remains an important part of participants' lives.
CHRONIC RESPIRATORY DISEASE
(2022)
Review
Respiratory System
Anna Brooke-Hollidge, Joy Conway, Adam Lewis
Summary: Non cystic-fibrosis bronchiectasis (NCFB) is a complex chronic respiratory disease with a higher prevalence among females, especially post-menopausal females. The effects of gender-specific hormones on bacterial load and physiotherapy management of people living with NCFB remain unknown, raising the need for further research to explore potential influences. Hormone replacement therapy may offer benefits in improving airway clearance, reducing exacerbations, and enhancing quality of life in females with NCFB.
THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE
(2021)
Article
Respiratory System
Keir E. J. Philip, Adam Lewis, Sara C. Buttery, Colm McCabe, Bishman Manivannan, Daisy Fancourt, Christopher M. Orton, Michael Polkey, Nicholas S. Hopkinson
Summary: Participating in singing has social and psychological benefits. The physiological demands of singing and its intensity as a physical activity were compared with treadmill walking at different speeds. Singing induced physiological responses consistent with moderate intensity activity, suggesting physical effects may contribute to the health benefits of singing.
BMJ OPEN RESPIRATORY RESEARCH
(2021)