Advances in Polygonatum sibiricum polysaccharides: Extraction, purification, structure, biosynthesis, and bioactivity

Polygonatum sibiricum has been used as food and medicine for thousands of years, and P. sibiricum polysaccharides (PSPs) have become the hot research spot due to their various health-promoting functions. Numerous studies have shown that PSPs possess huge potential in the application of functional food and medicine fields. However, the research status and features of the preparation process, molecular structure, and bioactivities of PSPs are unclear. Therefore, this review makes a comprehensive summary and proposes new insights and guidelines for the extraction, purification, structural features, biosynthesis, and multiple bioactivities of PSPs. Notably, it is concluded that PSPs mainly contain several types of polysaccharides, including fructan, pectin, galactomannan, glucomannans, arabinogalactan, and galactan, and multiple bioactivates, including osteogenic activity, anti-obesity, anti-diabetes, anti-depression, antioxidant, antiglycation, and protective effect against neurotoxicity and gut microbiota regulating activity. This review contributes to the structure-function study and resource utilization of P. sibiricum and its polysaccharides in food fields.

Automated summary

This review provides a comprehensive summary of the extraction, purification, structural features, biosynthesis, and multiple bioactivities of Polygonatum sibiricum polysaccharides (PSPs). The study highlights the potential of PSPs in functional food and medicine fields, and emphasizes the various polysaccharides and bioactivities present in PSPs. The findings contribute to the structure-function study and resource utilization of P. sibiricum and its polysaccharides in food fields.