Article
Chemistry, Analytical
Xiaoqing Tan, Yongpeng Liang, Yingying Ye, Zhihao Liu, Jianxin Meng, Fengyu Li
Summary: This study developed an explainable DL-assisted visualized fluorometric array-based sensing method for efficient qualitative and quantitative analysis of antibiotics. The convolutional neural network achieved high prediction accuracy and guided the improvement of the sensor array through a feedback mechanism.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Daniel de Almeida Cozendey, Renan de Oliveira Muniz, Rafael Cavalcante dos Santos, Cristiane Gimenes de Souza, Debora Franca de Andrade, Luiz Antonio D'Avila
Summary: The study developed a method for separating and quantifying free glycerol in biodiesel using SPE-HPLC-IR, which was validated for accuracy and precision, showing no statistical differences compared to the reference method. This proposed method offers a simple, quick, and effective alternative for determining free glycerol in biodiesel samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Food Science & Technology
Steven Mascrez, Sabine Danthine, Giorgia Purcaro
Summary: The study optimized a microwave-assisted saponification method combined with lab-made solid-phase extraction for the characterization of fats and oils, showing good recoveries, repeatabilities, and accuracy.
Article
Biochemical Research Methods
Pingping Wang, Fangling Wu, Fuxing Xu, Jun Jack Hu, Chuan-Fan Ding
Summary: The study developed a special poly solid-phase extraction (in-tube SPE) column for extraction analysis combined with UPLC, demonstrating excellent extraction efficiency, good precision, and satisfactory sensitivity for preservatives detection. The method is characterized by simple sample pretreatment, high throughput, rapid analysis, cost-effectiveness, and satisfactory sensitivity.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Mingming Xu, Liying Guo, Yicheng Wang, Qianqian Wang, Lin Hao, Chun Wang, Qiuhua Wu, Zhi Wang
Summary: Three aromatic heterocycle-based porous organic frameworks were prepared through Friedel-Crafts alkylation and showed high adsorption affinity for nitroimidazoles antibiotics. These frameworks were successfully applied as adsorbents for solid phase extraction before detection by high performance liquid chromatography-ultraviolet, providing a rapid and effective method for detecting trace residues in chicken meat.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Jun Wu, Wei Liu, Rui Zhu, Xiashi Zhu
Summary: A special self-designed device based on PILs-C-5 solid-phase extraction and HPLC was proposed for the online separation and analysis of RhB dye, with satisfactory results achieved through optimizing experimental parameters.
Article
Chemistry, Analytical
Aso Kaboodi, Hamid Mirzaei, Farzad Katiraee, Afshin Javadi, Mohammad Reza Afshar Mogaddam
Summary: In this study, a deep eutectic solvent-based microwave-assisted extraction was combined with ionic liquid-based temperature controlled liquid phase microextraction for the extraction of aflatoxins from cheese samples. The method achieved low limits of detection and quantification, high extraction recovery, acceptable enrichment factor, and good precision. It is considered as a green extraction method as it does not require the use of organic solvents.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Food Science & Technology
Guijie Li, Xu Zhang, Tingting Liu, Hongxiu Fan, Hongcheng Liu, Shangyu Li, Dawei Wang, Lan Ding
Summary: A convenient, cost-effective and fast method using dynamic microwave-assisted extraction and liquid phase microextraction based on the solidification of a floating drop was proposed for analyzing organochlorine pesticides in grains. The method showed good performance in terms of detection limits and recoveries of the pesticides. Compared with other extraction methods, this environmentally friendly approach is suitable for daily determination of organochlorine pesticides.
FOOD SCIENCE AND HUMAN WELLNESS
(2021)
Article
Plant Sciences
Cheng Song, Yunpeng Zhang, Muhammad Aamir Manzoor, Guohui Li
Summary: Jasmonate signaling is important for plant stress responses and secondary metabolism. This study established a rapid identification method for alkaloids in Dendrobium officinale and identified seven alkaloids and forty-nine other chemical substances in D. officinale. These findings provide insights into the composition of alkaloids in Dendrobium plants and offer a scientific method for their identification.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Chemistry, Analytical
Babak Khalilzadeh Kochameshki, Afshin Javadi, Mohammad Reza Afshar Mogaddam, Hamid Mirzaee, Mir Ali Farajzadeh
Summary: A simple pretreatment method based on the combination of microwave-assisted extraction and dispersive micro solid phase extraction was developed for the extraction of veterinary drugs from cow meat, liver, and kidney samples. The method showed acceptable repeatability, high extraction recoveries and enrichment factors, and low limits of detection and quantification.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Environmental Sciences
Attilio Naccarato, Antonella Tassone, Maria Martino, Rosangela Elliani, Francesca Sprovieri, Nicola Pirrone, Antonio Tagarelli
Summary: This paper presents a new method for quantifying chemicals in airborne particulate matter, utilizing microwave-assisted extraction and SPME, with optimal conditions determined through experimental design techniques. The developed protocol showed satisfactory results in terms of linearity, accuracy, and precision, demonstrating its value and eco-friendliness in real monitoring campaigns.
ENVIRONMENTAL POLLUTION
(2021)
Article
Chemistry, Analytical
Akbar Badali, Afshin Javadi, Mohammad Reza Afshar Mogaddam, Zohreh Mashak
Summary: Metal organic framework based dispersive solid phase extraction combined with dispersive liquid-liquid microextraction was used for the extraction of aflatoxin M1 and ochratoxin A from milk samples, and the analytes were determined by high performance liquid chromatography-fluorescent detector. The method showed satisfactory results, including low limits of detection, good quantification, high extraction recoveries and enrichment factors, and good repeatability. The method was successfully applied for the quantification of aflatoxin M1 and ochratoxin A in various raw cow's milk samples, and the effect of microwave irradiations in decontaminating them from milk samples was studied.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Yunliang Dai, Kyung Ho Row
Summary: Different chitosan derivatives were prepared to enhance the extraction efficiency of beta-sitosterol from edible oils, and the results indicated good extraction capabilities and acceptable recovery rates for these derivatives.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Chemistry, Applied
Sujittra Poorahong, Proespichaya Kanatharana, Chongdee Thammakhet-Buranachai, Panote Thavarungkul, Myo Myint Zaw
Summary: A gelatin aerogel tablet was used as a sorbent for the determination of PAHs in tea samples. The method showed good linearity, reproducibility, precision, and reusability, and had potential application in food safety.
Review
Chemistry, Inorganic & Nuclear
Anna A. Kotova, Didier Thiebaut, Jerome Vial, Antoine Tissot, Christian Serre
Summary: Analytical chemistry is crucial for separating complex mixtures, and Metal-organic frameworks (MOFs) are promising porous hybrid solids with unique physico-chemical properties, which can be applied in chromatography and solid-phase extraction to address challenges in these fields.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Cell Biology
Jintao Chen, Sifeng Mao, Ziyi He, Lijuan Yang, Jinfeng Zhang, Jin-Ming Lin, Zhi-Xiong Lin
Summary: This study investigated the protein distributions in MVNPs using CD34 immunofluorescence staining and MALDI-IMS technology, finding that MVNPs could be divided into two types and were associated with the prognosis of GBM. The findings may assist future research on therapy for GBM and predict prognosis.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
(2022)
Article
Biochemical Research Methods
Fangfang Fan, Ning Xu, Yucheng Sun, Xuanhao Li, Xinchang Gao, Xizhen Yi, Yi Zhang, Xianli Meng, Jin-Ming Lin
Summary: This study elucidated a new mechanism of Salidroside in reducing hypoxia-induced inflammation in microglia by regulating cellular energy metabolism. The hypoxic microenvironment of BV2 microglial cells was simulated in vitro using a cell microfluidic chip-mass spectrometry (CM-MS) system, and the real-time change of cell metabolites was investigated. The levels of hypoxia-related factors were also detected to confirm the metabolic mechanism of BV2 cells under hypoxia. The study found that Salidroside could invert the changes in cellular energy metabolism and identified two metabolites of Salidroside.
JOURNAL OF PROTEOME RESEARCH
(2022)
Editorial Material
Chemistry, Multidisciplinary
Shuo Feng, Jin-Ming Lin
SCIENCE CHINA-CHEMISTRY
(2022)
Article
Chemistry, Analytical
Shuang Han, Pengbo Zhang, Haifeng Lin, Haifang Li, Yanli Guo, Ning Xu, Jin-Ming Lin
Summary: The extracellular microenvironments play a crucial role in tumor metabolism, and a new integrated multi-channel chip-mass spectrometry system has been developed to online dynamic monitor the efficacy of 7-OHC on cells in acidic microenvironment. The results show that the acidic environment promotes the formation of inactive metabolites and weaken the anticancer effect of 7-OHC.
Review
Chemistry, Analytical
Yuting Shang, Xinran Xiang, Qinghua Ye, Qingping Wu, Jumei Zhang, Jin-Ming Lin
Summary: This review provides an overview of the application of microfluidic chips in detecting foodborne bacteria using different nanomaterials. The combination of nanomaterials with microfluidics improves the detection efficiency and sensitivity. The challenges in translating scientific research into product development are discussed, along with perspectives on future technological directions and potential applications.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Mei Zhao, Limei Luo, Yongxian Guo, Binglu Zhao, Xiangfeng Chen, Xingang Shi, Mashooq Khan, Jin-Ming Lin, Qiongzheng Hu
Summary: This study presents a novel amylase sensor based on pH paper strips for quantitative detection of AMS. The sensor showed high sensitivity with a detection limit of 0.017 U/mL and excellent specificity. It was successfully used for distinguishing amylase levels in healthy individuals and acute pancreatitis patients.
Article
Biochemical Research Methods
Chang Wang, Chaoying Zhang, Xinchang Gao, Jin-Ming Lin
Summary: Protein glycosylation, an important post-translational modification, plays a vital role in physiological processes. N-glycans exhibit structural diversity in linkages and branching styles and structure-specific glycan profiling can provide more potential biological information. In this study, N-glycans released from human serum samples were profiled using nanoLC-ESI-MS with PGC as a stationary phase. Alpha 2-3 neuraminidase was applied for distinguishing sialic acid linkage types. Significant differences in abundance were observed for 20 isomeric N-glycans between multiple myeloma cases and healthy controls. ROC analysis showed high diagnostic accuracy for MM, with 6 AUCs exceeding 0.80. PCA was used to establish differences among sample sets. Furthermore, these specific isomers have important clinical application value for early detection of multiple myeloma.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Binglu Zhao, Lubin Qi, Wenjun Tai, Mei Zhao, Xiangfeng Chen, Li Yu, Jianguo Shi, Xiao Wang, Jin-Ming Lin, Qiongzheng Hu
Summary: In this study, a paper-based flow sensor was developed based on the enzymatic hydrolysis-induced viscosity change in a stimuli-responsive polymer solution, enabling efficient and cost-effective label-free detection of hyaluronidase and its inhibitor. This method overcomes the limitations of traditional hydrogel-based sensors and shows great potential for various applications.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Nan Li, Weifei Zhang, Jing Lin, Gaowa Xing, Haifang Li, Jin-Ming Lin
Summary: This article introduces a method for simultaneous detection of multiple bacteria using mass tag-mediated surface engineering and mass spectrometry. This method eliminates the need for reliance on microbial mass spectra databases and shows potential application in milk safety monitoring.
ANALYTICAL CHEMISTRY
(2022)
Article
Biophysics
Shuo Feng, Qiang Zhang, Tianze Xie, Ying Hou, Jin-Ming Lin
Summary: In this work, an open microfluidic probe was established to investigate the dynamic signal transmission between single cells. Using injection-aspiration laminar flow, the probe provided stimulation to individual cells and observed signal transmission and cell motion through TM structures. This work provides a new perspective for single cell analysis and is of significance for studying tumor metastasis and invasion mechanisms.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Engineering, Chemical
Ming-Hui Li, Ling-Xi Zhao, Meng Xie, Na Li, Xiao-Li Wang, Ru-Song Zhao, Jin-Ming Lin
Summary: In this study, Li-Al LDH was prepared using the hydrothermal method and was found to effectively activate PMS for degrading SMX under specific conditions. The catalyst exhibited high degradation rate, good stability, and recoverability, making it a promising candidate for efficient wastewater catalytic treatment.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Tianze Xie, Qiang Zhang, Weifei Zhang, Shuo Feng, Jin-Ming Lin
Summary: Cell adhesion is crucial for cellular behaviors and life processes, but studying specific cells is challenging due to adhesion deficiencies or interference from surrounding cells. This study presents an open microfluidic system for culturing adherent single cells, offering high versatility and compatibility for various assaying methods.
Article
Chemistry, Analytical
Xiaonan Zheng, Yucheng Sun, Haifang Li, Nan Li, Xueji Zhang, Jin-Ming Lin
Summary: During tumorigenesis and development, cancer cells need to adapt to complex and dynamic signals in the tumor microenvironment. To study synergistic effects, researchers have proposed a biomimetic multi-factor stimulation platform that creates a controllable two-dimensional matrix environment with adjustable stiffness as a biomechanical factor and can introduce biochemical cues.
Article
Chemistry, Analytical
Supan Cheng, Mashooq Khan, Fangchao Yin, Wenli Wu, Tao Sun, Qiongzheng Hu, Jin-Ming Lin, Xiao Wang
Summary: In this study, a liquid crystal-based sensor was developed for the sensitive detection of uric acid and uricase in body fluids, showing potential for clinical analysis.
Article
Chemistry, Analytical
Zhaoxuan Fan, Yucheng Sun, Jin-Ming Lin
Summary: This study developed a method for molecular detection using a self-assembled inkjet printer. By generating discrete droplets, the inkjet printer enabled low-cost and practical droplet digital loop-mediated isothermal amplification. The results showed that this method successfully quantified HPV16.
