A Transversal Approach Combining In Silico, In Vitro and In Vivo Models to Describe the Metabolism of the Receptor Interacting Protein 1 Kinase Inhibitor Sibiriline
出版年份 2022 全文链接
标题
A Transversal Approach Combining In Silico, In Vitro and In Vivo Models to Describe the Metabolism of the Receptor Interacting Protein 1 Kinase Inhibitor Sibiriline
作者
关键词
-
出版物
Pharmaceutics
Volume 14, Issue 12, Pages 2665
出版商
MDPI AG
发表日期
2022-11-30
DOI
10.3390/pharmaceutics14122665
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular Network-Based Identification of Tramadol Metabolites in a Fatal Tramadol Poisoning
- (2022) Romain Magny et al. Metabolites
- Metabolite elucidation of 2‐fluoro‐deschloroketamine (2F‐DCK) using molecular networking across three complementary in vitro and in vivo models
- (2021) Thomas Gicquel et al. Drug Testing and Analysis
- A species specific metabolism leading to male rat reprotoxicity of Cyclamen aldehyde: in vivo and in vitro evaluation
- (2021) Andreas Natsch et al. FOOD AND CHEMICAL TOXICOLOGY
- In vivo and in vitro α-amanitin metabolism studies using molecular networking
- (2021) Brendan Le Daré et al. TOXICOLOGY LETTERS
- Molecular Networking for Drug Toxicities Studies: The Case of Hydroxychloroquine in COVID-19 Patients
- (2021) Pierre-Jean Ferron et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- In silico prediction, LC-HRMS/MS analysis, and targeted/untargeted data-mining workflow for the profiling of phenylfentanyl in vitro metabolites
- (2021) Annagiulia Di Trana et al. TALANTA
- Inhibitors Targeting RIPK1/RIPK3: Old and New Drugs
- (2020) Sofie Martens et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Comparative molecular networking analysis of a Rauwolfia plant powder and biological matrices in a fatal ingestion case
- (2020) Sophie Allard et al. Forensic Toxicology
- GLORYx: Prediction of the Metabolites Resulting from Phase 1 and Phase 2 Biotransformations of Xenobiotics
- (2020) Christina de Bruyn Kops et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Non-oxidative ethanol metabolism in human hepatic cells in vitro: Involvement of uridine diphospho-glucuronosyltransferase 1A9 in ethylglucuronide production
- (2020) Chloé Hugbart et al. TOXICOLOGY IN VITRO
- Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae Model
- (2020) Yu Mi Park et al. MOLECULES
- Pharmacokinetics of ginsenosides following repeated oral administration of red ginseng extract significantly differ between species of experimental animals
- (2020) Ji-Hyeon Jeon et al. ARCHIVES OF PHARMACAL RESEARCH
- New insights into quetiapine metabolism using molecular networking
- (2020) Brendan Le Daré et al. Scientific Reports
- BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identification
- (2019) Yannick Djoumbou-Feunang et al. Journal of Cheminformatics
- Death by inflammation: drug makers chase the master controller
- (2019) Cormac Sheridan NATURE BIOTECHNOLOGY
- Long-acting injectable antipsychotics (LAIs) for maintenance treatment of bipolar and schizoaffective disorders: A systematic review
- (2019) Isabella Pacchiarotti et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- In silico approaches and tools for the prediction of drug metabolism and fate: A review
- (2019) Sayada Reemsha Kazmi et al. COMPUTERS IN BIOLOGY AND MEDICINE
- Pharmacokinetics and Clinical Implications of Semaglutide: A New Glucagon-Like Peptide (GLP)-1 Receptor Agonist
- (2018) Sylvie Hall et al. CLINICAL PHARMACOKINETICS
- In vitro Characterization of NPS Metabolites Produced by Human Liver Microsomes and the HepaRG Cell Line Using Liquid Chromatographyhigh Resolution Mass Spectrometry (LC-HRMS) Analysis: Application to Furanyl Fentanyl
- (2018) Camille Richeval et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Strategy for Extending Half-life in Drug Design and Its Significance
- (2018) Hakan Gunaydin et al. ACS Medicinal Chemistry Letters
- Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes
- (2018) Nicolas Quesnot et al. ARCHIVES OF TOXICOLOGY
- Computational methods and tools to predict cytochrome P450 metabolism for drug discovery
- (2018) Jonathan D. Tyzack et al. Chemical Biology & Drug Design
- Application of a molecular networking approach for clinical and forensic toxicology exemplified in three cases involving 3-MeO-PCP, doxylamine, and chlormequat
- (2018) Sophie Allard et al. Drug Testing and Analysis
- Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis
- (2017) Fabienne Le Cann et al. FEBS Journal
- Adequate plasma drug concentrations suggest that amoxicillin can be administered by continuous infusion using elastomeric pumps
- (2017) Lyne Arensdorff et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases
- (2017) Philip A. Harris et al. JOURNAL OF MEDICINAL CHEMISTRY
- Diphenidine, a new psychoactive substance: metabolic fate elucidated with rat urine and human liver preparations and detectability in urine using GC-MS, LC-MSn, and LC-HR-MSn
- (2016) Carina S. D. Wink et al. Drug Testing and Analysis
- Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
- (2016) Mingxun Wang et al. NATURE BIOTECHNOLOGY
- Predicting drug metabolism: experiment and/or computation?
- (2015) Johannes Kirchmair et al. NATURE REVIEWS DRUG DISCOVERY
- Machine Learning Techniques and Drug Design
- (2012) J.C. Gertrudes et al. CURRENT MEDICINAL CHEMISTRY
- MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data
- (2010) Tomáš Pluskal et al. BMC BIOINFORMATICS
- ProteoWizard: open source software for rapid proteomics tools development
- (2008) Darren Kessner et al. BIOINFORMATICS
- Recent Advances in QSAR and Their Applications in Predicting the Activities of Chemical Molecules, Peptides and Proteins for Drug Design
- (2008) Qi-Shi Du et al. CURRENT PROTEIN & PEPTIDE SCIENCE
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