Stomatal CO 2 /bicarbonate sensor consists of two interacting protein kinases, Raf-like HT1 and non-kinase-activity requiring MPK12/MPK4

Chemical control of stomatal function and development

(2021) Toshinori Kinoshita et al.   CURRENT OPINION IN PLANT BIOLOGY

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Deep geometric representations for modeling effects of mutations on protein-protein binding affinity

(2021) Xianggen Liu et al.   PLoS Computational Biology

Split the Charge Difference in Two! A Rule of Thumb for Adding Proper Amounts of Ions in MD Simulations

(2020) Matías R. Machado et al.   Journal of Chemical Theory and Computation

MAP3Kinase-dependent SnRK2-kinase activation is required for abscisic acid signal transduction and rapid osmotic stress response

(2020) Yohei Takahashi et al.   Nature Communications

The Circadian Clock Influences the Long-Term Water Use Efficiency of Arabidopsis

(2020) Noriane M. L. Simon et al.   PLANT PHYSIOLOGY

ff19SB: Amino-Acid-Specific Protein Backbone Parameters Trained against Quantum Mechanics Energy Surfaces in Solution

(2019) Chuan Tian et al.   Journal of Chemical Theory and Computation

Acceleration of biomolecular kinetics in Gaussian accelerated molecular dynamics

(2018) Yinglong Miao   JOURNAL OF CHEMICAL PHYSICS

SLTCAP: A Simple Method for Calculating the Number of Ions Needed for MD Simulation

(2018) Jeremy D. Schmit et al.   Journal of Chemical Theory and Computation

Carbonic Anhydrase Mutants inZea maysHave Altered Stomatal Responses to Environmental Signals

(2018) Allison R. Kolbe et al.   PLANT PHYSIOLOGY

Abscisic acid-induced degradation ofArabidopsisguanine nucleotide exchange factor requires calcium-dependent protein kinases

(2018) Zixing Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitogen-activated protein kinases MPK4 and MPK12 are key components mediating CO2 -induced stomatal movements

(2018) Kadri Tõldsepp et al.   PLANT JOURNAL

Insights into the Molecular Mechanisms of CO2-Mediated Regulation of Stomatal Movements

(2018) Jingbo Zhang et al.   CURRENT BIOLOGY

Gaussian accelerated molecular dynamics for elucidation of drug pathways

(2018) Apurba Bhattarai et al.   Expert Opinion on Drug Discovery

The receptor-like pseudokinase GHR1 is required for stomatal closure

(2018) Maija Sierla et al.   PLANT CELL

Identification of SLAC1 anion channel residues required for CO2/bicarbonate sensing and regulation of stomatal movements

(2018) Jingbo Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blue light and CO2 signals converge to regulate light-induced stomatal opening

(2017) Asami Hiyama et al.   Nature Communications

OpenMM 7: Rapid development of high performance algorithms for molecular dynamics

(2017) Peter Eastman et al.   PLoS Computational Biology

Ecological interactions and the fitness effect of water-use efficiency: Competition and drought alter the impact of naturalMPK12alleles inArabidopsis

(2016) Brandon E. Campitelli et al.   ECOLOGY LETTERS

Dominant and recessive mutations in the Raf-like kinaseHT1gene completely disrupt stomatal responses to CO2in Arabidopsis

(2016) Mimi Hashimoto-Sugimoto et al.   JOURNAL OF EXPERIMENTAL BOTANY

A Dominant Mutation in the HT1 Kinase Uncovers Roles of MAP Kinases and GHR1 in CO2-Induced Stomatal Closure

(2016) Hanna Hõrak et al.   PLANT CELL

Leveraging abscisic acid receptors for efficient water use inArabidopsis

(2016) Zhenyu Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural Variation in Arabidopsis Cvi-0 Accession Reveals an Important Role of MPK12 in Guard Cell CO2 Signaling

(2016) Liina Jakobson et al.   PLOS BIOLOGY

Gaussian Accelerated Molecular Dynamics: Unconstrained Enhanced Sampling and Free Energy Calculation

(2015) Yinglong Miao et al.   Journal of Chemical Theory and Computation

Building Water Models: A Different Approach

(2014) Saeed Izadi et al.   Journal of Physical Chemistry Letters

Variation in MPK12 affects water use efficiency in Arabidopsis and reveals a pleiotropic link between guard cell size and ABA response

(2014) D. L. Des Marais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald

(2013) Romelia Salomon-Ferrer et al.   Journal of Chemical Theory and Computation

An integrated model of stomatal development and leaf physiology

(2013) Graham J. Dow et al.   NEW PHYTOLOGIST

New Approaches to the Biology of Stomatal Guard Cells

(2013) Juntaro Negi et al.   PLANT AND CELL PHYSIOLOGY

SPFP: Speed without compromise—A mixed precision model for GPU accelerated molecular dynamics simulations

(2012) Scott Le Grand et al.   COMPUTER PHYSICS COMMUNICATIONS

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized Born

(2012) Andreas W. Götz et al.   Journal of Chemical Theory and Computation

A Plasma Membrane Receptor Kinase, GHR1, Mediates Abscisic Acid- and Hydrogen Peroxide-Regulated Stomatal Movement inArabidopsis

(2012) Deping Hua et al.   PLANT CELL

Central functions of bicarbonate in S-type anion channel activation and OST1 protein kinase in CO2signal transduction in guard cell

(2011) Shaowu Xue et al.   EMBO JOURNAL

LowModeMD—Implicit Low-Mode Velocity Filtering Applied to Conformational Search of Macrocycles and Protein Loops

(2010) Paul Labute   Journal of Chemical Information and Modeling

New GATEWAY vectors for High Throughput Analyses of Protein–Protein Interactions by Bimolecular Fluorescence Complementation

(2009) Christian Gehl et al.   Molecular Plant

Carbonic anhydrases are upstream regulators of CO2-controlled stomatal movements in guard cells

(2009) Honghong Hu et al.   NATURE CELL BIOLOGY

Stimulation of Mammalian G-protein-responsive Adenylyl Cyclases by Carbon Dioxide

(2008) Philip D. Townsend et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SLAC1 is required for plant guard cell S-type anion channel function in stomatal signalling

(2008) Triin Vahisalu et al.   NATURE

Multicolor bimolecular fluorescence complementation reveals simultaneous formation of alternative CBL/CIPK complexesin planta

(2008) Rainer Waadt et al.   PLANT JOURNAL

Isolation of a strong Arabidopsis guard cell promoter and its potential as a research tool

(2008) Yingzhen Yang et al.   Plant Methods