KLF4 regulates adult lung tumor-initiating cells and represses K-Ras-mediated lung cancer

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Alveolar progenitor and stem cells in lung development, renewal and cancer

(2014) Tushar J. Desai et al.   NATURE

Diverse cells at the origin of lung adenocarcinoma: Table 1.

(2014) Samuel P. Rowbotham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple cells-of-origin of mutant K-Ras–induced mouse lung adenocarcinoma

(2014) Kate D. Sutherland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDAC1 and Klf4 interplay critically regulates human myeloid leukemia cell proliferation

(2014) Y Huang et al.   Cell Death & Disease

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations

(2013) David E. Reuss et al.   ACTA NEUROPATHOLOGICA

Impairing squamous differentiation by Klf4 deletion is sufficient to initiate tongue carcinoma development upon K- Ras activation in mice

(2013) Marianela Abrigo et al.   CARCINOGENESIS

Type 2 alveolar cells are stem cells in adult lung

(2013) Christina E. Barkauskas et al.   JOURNAL OF CLINICAL INVESTIGATION

HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

(2013) Claudia Simões-Pires et al.   Molecular Neurodegeneration

Transcription Factor Klf4, Induced in the Lung by Oxygen at Birth, Regulates Perinatal Fibroblast and Myofibroblast Differentiation

(2013) Jyh-Chang Jean et al.   PLoS One

Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma

(2013) S. Mainardi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7, KLF4, AKT1, and SMO

(2013) V. E. Clark et al.   SCIENCE

Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma

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TLR9- and Src-dependent expression of Krueppel-like factor 4 controls interleukin-10 expression in pneumonia

(2012) Janine Zahlten et al.   EUROPEAN RESPIRATORY JOURNAL

Histone deacetylases and cancer

(2012) Bruna Barneda-Zahonero et al.   Molecular Oncology

Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma

(2012) X. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of the Potential Marker for Intestinal Cells, Bmi1, by β-Catenin and the Zinc Finger Protein KLF4

(2011) Tianxin Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trichostatin A prevents neointimal hyperplasia via activation of Krüppel like factor 4

(2011) Hae Jin Kee et al.   VASCULAR PHARMACOLOGY

Putative Tumor-Suppressive Function of Kruppel-Like Factor 4 in Primary Lung Carcinoma

(2009) W. Hu et al.   CLINICAL CANCER RESEARCH

Krüppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy

(2009) Hae Jin Kee et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

KLF4 Interacts with  -Catenin/TCF4 and Blocks p300/CBP Recruitment by  -Catenin

(2009) P. M. Evans et al.   MOLECULAR AND CELLULAR BIOLOGY

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

(2009) Michel DuPage et al.   Nature Protocols

Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: Effects of endothelin-1, oxidative stress and cytokines

(2008) Timothy E. Cullingford et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy

(2008) Jennifer S. Carew et al.   CANCER LETTERS

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

(2008) Xiang-Jiao Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

(2008) J. S. Dovey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA