PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD)
出版年份 2015 全文链接
标题
PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD)
作者
关键词
-
出版物
CELL CYCLE
Volume 14, Issue 11, Pages 1716-1729
出版商
Informa UK Limited
发表日期
2015-05-28
DOI
10.1080/15384101.2015.1033595
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Huntington disease: natural history, biomarkers and prospects for therapeutics
- (2014) Christopher A. Ross et al. Nature Reviews Neurology
- Phosphorylation of Mutant Huntingtin at Serine 116 Modulates Neuronal Toxicity
- (2014) Erin E. Watkin et al. PLoS One
- JMJD6 Promotes Colon Carcinogenesis through Negative Regulation of p53 by Hydroxylation
- (2014) Feng Wang et al. PLOS BIOLOGY
- Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery
- (2013) M. Bezzi et al. GENES & DEVELOPMENT
- Epigenetic Mechanisms of Neurodegeneration in Huntington’s Disease
- (2013) Junghee Lee et al. Neurotherapeutics
- PRMT5-mediated histone H4 arginine-3 symmetrical dimethylation marks chromatin at G + C-rich regions of the mouse genome
- (2013) Michael Girardot et al. NUCLEIC ACIDS RESEARCH
- Structure of the Arginine Methyltransferase PRMT5-MEP50 Reveals a Mechanism for Substrate Specificity
- (2013) Meng-Chiao Ho et al. PLoS One
- Targeting H3K4 trimethylation in Huntington disease
- (2013) M. Vashishtha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis
- (2012) Tamara Ratovitski et al. CELL CYCLE
- Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes
- (2012) The HD iPSC Consortium Cell Stem Cell
- Identification of Novel Potentially Toxic Oligomers Formedin Vitrofrom Mammalian-derived Expanded huntingtin Exon-1 Protein
- (2012) Leslie G. Nucifora et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Histone methylation: a dynamic mark in health, disease and inheritance
- (2012) Eric L. Greer et al. NATURE REVIEWS GENETICS
- Crystal structure of the human PRMT5:MEP50 complex
- (2012) S. Antonysamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein Arginine Methyltransferase Prmt5-Mep50 Methylates Histones H2A and H4 and the Histone Chaperone Nucleoplasmin inXenopus laevisEggs
- (2011) Carola Wilczek et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Arginine methylation of RNA-binding proteins regulates cell function and differentiation
- (2011) Ernest Blackwell et al. MOLECULAR REPRODUCTION AND DEVELOPMENT
- Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase
- (2010) Priya Aggarwal et al. CANCER CELL
- Functional Gene Expression Profiling in Yeast Implicates Translational Dysfunction in Mutant Huntingtin Toxicity
- (2010) Eran Tauber et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Role for Huntington Disease Protein in Dendritic RNA Granules
- (2010) Jeffrey N. Savas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RioK1, a New Interactor of Protein Arginine Methyltransferase 5 (PRMT5), Competes with pICln for Binding and Modulates PRMT5 Complex Composition and Substrate Specificity
- (2010) Gernot Guderian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Huntington's disease: from molecular pathogenesis to clinical treatment
- (2010) Christopher A Ross et al. LANCET NEUROLOGY
- Localization of BDNF mRNA with the Huntington's disease protein in rat brain
- (2010) Bin Ma et al. Molecular Neurodegeneration
- The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans
- (2009) S. S. Wolf CELLULAR AND MOLECULAR LIFE SCIENCES
- Huntingtin facilitates polycomb repressive complex 2
- (2009) Ihn Sik Seong et al. HUMAN MOLECULAR GENETICS
- Mutant Huntingtin N-terminal Fragments of Specific Size Mediate Aggregation and Toxicity in Neuronal Cells
- (2009) Tamara Ratovitski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing
- (2009) Quan Zhao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity
- (2009) S. Subramaniam et al. SCIENCE
- Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing
- (2009) Celia J. Webby et al. SCIENCE
- Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins
- (2008) Phillip Hahn et al. BMC GENOMICS
- The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5
- (2008) Matthieu Lacroix et al. EMBO REPORTS
- Pathogenic Mechanisms of a Polyglutamine-mediated Neurodegenerative Disease, Spinocerebellar Ataxia Type 1
- (2008) Huda Y. Zoghbi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dysregulation of Gene Expression in Primary Neuron Models of Huntington's Disease Shows That Polyglutamine-Related Effects on the Striatal Transcriptome May Not Be Dependent on Brain Circuitry
- (2008) H. Runne et al. JOURNAL OF NEUROSCIENCE
- Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1
- (2008) Janghoo Lim et al. NATURE
- Arginine methylation regulates the p53 response
- (2008) Martin Jansson et al. NATURE CELL BIOLOGY
- Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies
- (2008) J. N. Savas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started