Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach

Development and verification of an endogenous PBPK model to inform hydrocortisone replacement dosing in children and adults with cortisol deficiency

(2021) Jennifer J Bonner et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Paediatric population pharmacokinetic modelling to assess hydrocortisone replacement dosing regimens in young children

(2020) Robin Michelet et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Perspectives on Model‐Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations

(2020) Franziska Kluwe et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The circadian rhythm of corticosteroid-binding globulin has little impact on cortisol exposure after hydrocortisone dosing

(2019) Johanna Melin et al.   CLINICAL ENDOCRINOLOGY

Pharmacokinetic–Pharmacodynamic Modeling in Pediatric Drug Development, and the Importance of Standardized Scaling of Clearance

(2018) Eva Germovsek et al.   CLINICAL PHARMACOKINETICS

PBPK in Preterm and Term Neonates: A Review

(2018) Robin Michelet et al.   CURRENT PHARMACEUTICAL DESIGN

Longitudinal Assessment of Illnesses, Stress Dosing, and Illness Sequelae in Patients With Congenital Adrenal Hyperplasia

(2018) Diala El-Maouche et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The use of PBPK modeling across the pediatric age range using propofol as a case

(2018) Robin Michelet et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline

(2016) Stefan R. Bornstein et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diagnosis and management of adrenal insufficiency

(2015) Irina Bancos et al.   Lancet Diabetes & Endocrinology

Variation in absorption and half-life of hydrocortisone influence plasma cortisol concentrations

(2014) Peter C. Hindmarsh et al.   CLINICAL ENDOCRINOLOGY

Diminished 11β-Hydroxysteroid Dehydrogenase Type 2 Activity Is Associated With Decreased Weight and Weight Gain Across the First Year of Life

(2014) Samantha L. Rogers et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Relationship Between Final Height and Health Outcomes in Adults With Congenital Adrenal Hyperplasia: United Kingdom Congenital Adrenal Hyperplasia Adult Study Executive (CaHASE)

(2014) T. S. Han et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Increased Mortality in Patients With Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency

(2014) Henrik Falhammar et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Combining the ‘bottom up’ and ‘top down’ approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

(2013) Nikolaos Tsamandouras et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Clinical Characteristics of a Cohort of 244 Patients with Congenital Adrenal Hyperplasia

(2012) Gabriela P. Finkielstain et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Role of modeling and simulation in pediatric investigation plans

(2011) Efthymios Manolis et al.   PEDIATRIC ANESTHESIA

Management of the child with congenital adrenal hyperplasia

(2009) Peter C. Hindmarsh   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Development of CYP2D6 and CYP3A4 in the First Year of Life

(2007) TN Johnson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS