How to evaluate the patient with a suspected mast cell disorder and how/when to manage symptoms

Tyrosine kinase inhibitors for the treatment of indolent systemic mastocytosis: Are we there yet?

(2022) Cem Akin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Standards of Genetic Testing in the Diagnosis and Prognostication of Systemic Mastocytosis in 2022: Recommendations of the EU-US Cooperative Group

(2022) Gregor Hoermann et al.   Journal of Allergy and Clinical Immunology-In Practice

Global Classification of Mast Cell Activation Disorders An ICD-10-CM-Adjusted Proposal of the ECNM-AIM Consortium

(2022) Peter Valent et al.   Journal of Allergy and Clinical Immunology-In Practice

Nontryptase Urinary and Hematologic Biomarkers of Mast Cell Expansion and Mast Cell Activation: Status 2022

(2022) J.H. Butterfield   Journal of Allergy and Clinical Immunology-In Practice

Available and emerging therapies for bona fide advanced systemic mastocytosis and primary eosinophilic neoplasms

(2022) Jason Gotlib   Hematology-American Society of Hematology Education Program

Systemic mastocytosis in adults: 2021 Update on diagnosis, risk stratification and management

(2021) Animesh Pardanani   AMERICAN JOURNAL OF HEMATOLOGY

Molecular Background, Clinical Features and Management of Pediatric Mastocytosis: Status 2021

(2021) Magdalena Lange et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hereditary alpha tryptasemia is not associated with specific clinical phenotypes

(2021) Madeleine B. Chollet et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Efficacy and safety of avapritinib in advanced systemic mastocytosis: interim analysis of the phase 2 PATHFINDER trial

(2021) Jason Gotlib et al.   NATURE MEDICINE

Safety and efficacy of avapritinib in advanced systemic mastocytosis: the phase 1 EXPLORER trial

(2021) Daniel J. DeAngelo et al.   NATURE MEDICINE

New Developments in Diagnosis, Prognostication, and Treatment of Advanced Systemic Mastocytosis

(2020) Andreas Reiter et al.   BLOOD

Omalizumab in the treatment of adult patients with mastocytosis: a systematic review

(2020) Fatma Jendoubi et al.   CLINICAL AND EXPERIMENTAL ALLERGY

PIONEER: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Avapritinib in Patients with Indolent or Smoldering Systemic Mastocytosis (SM) With Symptoms Inadequately Controlled by Standard Therapy

(2020) Cem Akin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Hereditary alpha tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis

(2020) Georg Greiner et al.   BLOOD

Heritable risk for severe anaphylaxis associated with increased α-tryptase-encoding germline copy number at TPSAB1

(2020) Jonathan J. Lyons et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mast Cell Activation Syndrome and Mastocytosis: Initial Treatment Options and Long-Term Management

(2019) Mariana Castells et al.   Journal of Allergy and Clinical Immunology-In Practice

Multidisciplinary Challenges in Mastocytosis and How to Address with Personalized Medicine Approaches

(2019) Peter Valent et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hymenoptera Anaphylaxis as a Clonal Mast Cell Disorder

(2018) Patrizia Bonadonna et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Systemic Mastocytosis, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology

(2018) Jason Gotlib et al.   Journal of the National Comprehensive Cancer Network

Management of Mastocytosis in Pregnancy: A Review

(2017) Dawn Lei et al.   Journal of Allergy and Clinical Immunology-In Practice

Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology

(2016) Karin Hartmann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical, immunophenotypic, and molecular characteristics of well-differentiated systemic mastocytosis

(2016) Iván Álvarez-Twose et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

(2016) Jonathan J Lyons et al.   NATURE GENETICS

Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis

(2016) Jason Gotlib et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endocrine manifestations of systemic mastocytosis in bone

(2016) Loren Wissner Greene et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Mast Cells, Mastocytosis, and Related Disorders

(2015) Theoharis C. Theoharides et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Clinicopathologic Study of 24 Cases of Systemic Mastocytosis Involving the Gastrointestinal Tract and Assessment of Mucosal Mast Cell Density in Irritable Bowel Syndrome and Asymptomatic Patients

(2014) Leona A. Doyle et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Epidemiology, Prognosis, and Risk Factors in Mastocytosis

(2014) Knut Brockow   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Myelomastocytic leukemia: histopathological features, diagnostic criteria and differential diagnosis

(2014) Hans-Peter Horny et al.   Expert Review of Hematology

Perioperative Management of Patients with Mastocytosis

(2013) Pascale Dewachter et al.   ANESTHESIOLOGY

Comprehensive mutational profiling in advanced systemic mastocytosis

(2013) J. Schwaab et al.   BLOOD

Mast cell sarcoma: a rare and potentially under-recognized diagnostic entity with specific therapeutic implications

(2012) Russell J H Ryan et al.   MODERN PATHOLOGY

Definitions, Criteria and Global Classification of Mast Cell Disorders with Special Reference to Mast Cell Activation Syndromes: A Consensus Proposal

(2011) Peter Valent et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Anaphylaxis in patients with mastocytosis: a study on history, clinical features and risk factors in 120 patients

(2010) K. Brockow et al.   ALLERGY

Clinical, biological, and molecular characteristics of clonal mast cell disorders presenting with systemic mast cell activation symptoms

(2010) Iván Álvarez-Twose et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mast cell activation syndrome: Proposed diagnostic criteria

(2010) Cem Akin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY