Replication-induced DNA damage after PARP inhibition causes G2delay, and cell line-dependent apoptosis, necrosis and multinucleation
出版年份 2015 全文链接
标题
Replication-induced DNA damage after PARP inhibition causes G2delay, and cell line-dependent apoptosis, necrosis and multinucleation
作者
关键词
-
出版物
CELL CYCLE
Volume 14, Issue 20, Pages 3248-3260
出版商
Informa UK Limited
发表日期
2015-08-28
DOI
10.1080/15384101.2015.1085137
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- RAD51C-Deficient Cancer Cells Are Highly Sensitive to the PARP Inhibitor Olaparib
- (2013) A. Min et al. MOLECULAR CANCER THERAPEUTICS
- 5-Aza-2′-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair
- (2013) Manuel Luís Orta et al. NUCLEIC ACIDS RESEARCH
- Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib
- (2012) Anneleen Daemen et al. BREAST CANCER RESEARCH AND TREATMENT
- Phase I study to assess the safety and tolerability of olaparib in combination with bevacizumab in patients with advanced solid tumours
- (2012) E Dean et al. BRITISH JOURNAL OF CANCER
- Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
- (2012) J. Murai et al. CANCER RESEARCH
- Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1
- (2012) S. Ying et al. CANCER RESEARCH
- Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53
- (2012) Chris T. Williamson et al. EMBO Molecular Medicine
- Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase
- (2012) Sabrina Köcher et al. NUCLEIC ACIDS RESEARCH
- MRE11 Deficiency Increases Sensitivity to Poly(ADP-ribose) Polymerase Inhibition in Microsatellite Unstable Colorectal Cancers
- (2011) E. Vilar et al. CANCER RESEARCH
- γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization
- (2011) Markus Löbrich et al. CELL CYCLE
- ATM-dependent ERK signaling via AKT in response to DNA double-strand breaks
- (2011) Ashraf Khalil et al. CELL CYCLE
- Three independent mechanisms for arrest in G2after ionizing radiation
- (2011) Kirsti Solberg Landsverk et al. CELL CYCLE
- Inhibition of poly(ADP-ribose) polymerase (PARP) and ataxia telangiectasia mutated (ATM) on the chemosensitivity of mantle cell lymphoma to agents that induce DNA strand breaks
- (2011) Radha M. Golla et al. HEMATOLOGICAL ONCOLOGY
- The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo
- (2010) V. J. Weston et al. BLOOD
- Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling
- (2010) E. M. Hartmann et al. BLOOD
- Poly(ADP-Ribose) Polymerase Is Hyperactivated in Homologous Recombination-Defective Cells
- (2010) P. Gottipati et al. CANCER RESEARCH
- Anti-leukemic activity of Dasatinib in both p53wild-type and p53mutated B malignant cells
- (2010) Raffaella Bosco et al. INVESTIGATIONAL NEW DRUGS
- Poly(ADP)-Ribose Polymerase Inhibition: Frequent Durable Responses inBRCACarrier Ovarian Cancer Correlating With Platinum-Free Interval
- (2010) Peter C. Fong et al. JOURNAL OF CLINICAL ONCOLOGY
- Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
- (2010) Andrew Tutt et al. LANCET
- Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
- (2010) M William Audeh et al. LANCET
- ATM Deficiency Sensitizes Mantle Cell Lymphoma Cells to Poly(ADP-Ribose) Polymerase-1 Inhibitors
- (2010) C. T. Williamson et al. MOLECULAR CANCER THERAPEUTICS
- Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate
- (2010) C. E. Strom et al. NUCLEIC ACIDS RESEARCH
- MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks
- (2009) Beth A. Helmink et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Role of mammalian Mre11 in classical and alternative nonhomologous end joining
- (2009) Anyong Xie et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells
- (2009) Emilie Rass et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity
- (2008) Christopher J. Lord et al. DNA REPAIR
- A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor
- (2008) Nicholas C Turner et al. EMBO JOURNAL
- 4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1
- (2008) Keith A. Menear et al. JOURNAL OF MEDICINAL CHEMISTRY
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
- Toward specific functions of poly(ADP-ribose) polymerase-2
- (2008) José Yélamos et al. TRENDS IN MOLECULAR MEDICINE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now