Molecular mechanism of statin-mediated LOX-1 inhibition

Synchronization of the cell cycle using Lovastatin

(2014) Sonia JavanMoghadam-Kamrani et al.   CELL CYCLE

Simulative and experimental investigation on the cleavage site that generates the soluble human LOX-1

(2013) Silvia Biocca et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Design of a novel LOX-1 receptor antagonist mimicking the natural substrate

(2013) Mattia Falconi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular dynamics of the full-length p53 monomer

(2013) Giovanni Chillemi et al.   CELL CYCLE

SwissParam: A fast force field generation tool for small organic molecules

(2011) Vincent Zoete et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Structural-dynamical investigation of the ZnuA histidine-rich loop: involvement in zinc management and transport

(2011) Mattia Falconi et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Open Babel: An open chemical toolbox

(2011) Noel M O'Boyle et al.   Journal of Cheminformatics

Surface plasmon resonance study on functional significance of clustered organization of lectin-like oxidized LDL receptor (LOX-1)

(2010) Izuru Ohki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Protein Thermostability Calculations Using Alchemical Free Energy Simulations

(2010) Daniel Seeliger et al.   BIOPHYSICAL JOURNAL

Statin loading for acute coronary syndromes

(2010) Annunziata Nusca et al.   CURRENT OPINION IN CARDIOLOGY

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Oligomerization is required for the activity of recombinant soluble LOX-1

(2009) Wei Cao et al.   FEBS Journal

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Novel Approaches for Preventing or Limiting Events (Naples) II Trial

(2009) Carlo Briguori et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Functional Analysis and Molecular Dynamics Simulation of LOX-1 K167N Polymorphism Reveal Alteration of Receptor Activity

(2009) Silvia Biocca et al.   PLoS One

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding

(2008) Omar L. Francone et al.   JOURNAL OF LIPID RESEARCH

The splice variant LOXIN inhibits LOX-1 receptor function through hetero-oligomerization

(2008) Silvia Biocca et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Pleiotropic effects of statin therapy: molecular mechanisms and clinical results

(2008) Chao-Yung Wang et al.   TRENDS IN MOLECULAR MEDICINE

LOX-1 abrogation reduces myocardial ischemia–reperfusion injury in mice

(2007) Changping Hu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY