ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol

IL-1 Mediates Tissue-Specific Inflammation and Severe Respiratory Failure in COVID-19

(2022) Georgios Renieris et al.   Journal of Innate Immunity

Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial

(2021) Evdoxia Kyriazopoulou et al.   NATURE MEDICINE

ESCAPE: An Open-Label Trial of Personalized Immunotherapy in Critically lll COVID-19 Patients

(2021) Eleni Karakike et al.   Journal of Innate Immunity

Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial

(2021) Jozefien Declercq et al.   Lancet Respiratory Medicine

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome

(2016) Bita Shakoory et al.   CRITICAL CARE MEDICINE

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sepsis: Current Dogma and New Perspectives

(2014) Clifford S. Deutschman et al.   IMMUNITY

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

(2013) Richard S Hotchkiss et al.   LANCET INFECTIOUS DISEASES

Reversal of Immunoparalysis in HumansIn Vivo

(2012) Jenneke Leentjens et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effect of Empirical Treatment With Moxifloxacin and Meropenem vs Meropenem on Sepsis-Related Organ Dysfunction in Patients With Severe Sepsis

(2012) Frank M. Brunkhorst   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Intensive Insulin Therapy and Pentastarch Resuscitation in Severe Sepsis

(2008) Frank M. Brunkhorst et al.   NEW ENGLAND JOURNAL OF MEDICINE