Sex differences in response to miRNA-34a therapy in mouse models of cardiac disease: identification of sex-, disease- and treatment-regulated miRNAs

Identification of miR-34 regulatory networks in settings of disease and antimiR-therapy: Implications for treating cardiac pathology and other diseases

(2016) Jenny Y.Y. Ooi et al.   RNA Biology

Inhibition of miR-154 Protects Against Cardiac Dysfunction and Fibrosis in a Mouse Model of Pressure Overload

(2016) Bianca C. Bernardo et al.   Scientific Reports

Deep sequencing of small RNA facilitates tissue and sex associated microRNA discovery in zebrafish

(2015) Candida Vaz et al.   BMC GENOMICS

MicroRNA-34a Plays a Key Role in Cardiac Repair and Regeneration Following Myocardial InfarctionNovelty and Significance

(2015) Yanfei Yang et al.   CIRCULATION RESEARCH

Gender-specific medicine in the genomic era

(2015) M. J. Legato   CLINICAL SCIENCE

miRNA therapeutics: a new class of drugs with potential therapeutic applications in the heart

(2015) Bianca C Bernardo et al.   Future Medicinal Chemistry

miR-34: from bench to bedside

(2015) Massimiliano Agostini et al.   Oncotarget

Therapeutic silencing of miR-652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy

(2014) Bianca C. Bernardo et al.   FASEB JOURNAL

The therapeutic potential of miRNAs regulated in settings of physiological cardiac hypertrophy

(2014) Jenny YY Ooi et al.   Future Medicinal Chemistry

Silencing of miR-34a Attenuates Cardiac Dysfunction in a Setting of Moderate, but Not Severe, Hypertrophic Cardiomyopathy

(2014) Bianca C. Bernardo et al.   PLoS One

MicroRNA-34a: a potential therapeutic target in human cancer

(2014) X J Li et al.   Cell Death & Disease

The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice

(2014) Geeta Sapra et al.   Nature Communications

Influence of sex differences on microRNA gene regulation in disease

(2014) Salil Sharma et al.   Biology of Sex Differences

Circulating p53-Responsive MicroRNAs Are Predictive Indicators of Heart Failure After Acute Myocardial Infarction

(2013) Sen Matsumoto et al.   CIRCULATION RESEARCH

Regulation of Cardiac MicroRNAs by Cardiac MicroRNAs

(2013) Scot J. Matkovich et al.   CIRCULATION RESEARCH

Sex- and estrogen-dependent regulation of a miRNA network in the healthy and hypertrophied heart

(2013) Ana Maria Queirós et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

MicroRNA-34a regulates cardiac ageing and function

(2013) Reinier A. Boon et al.   NATURE

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

(2013) Yasuhiro Maejima et al.   NATURE MEDICINE

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

miR-222 contributes to sex-dimorphic cardiac eNOS expression via ets-1

(2013) Alicia M. Evangelista et al.   PHYSIOLOGICAL GENOMICS

A Panel of 4 microRNAs Facilitates the Prediction of Left Ventricular Contractility after Acute Myocardial Infarction

(2013) Yvan Devaux et al.   PLoS One

Functions of MicroRNAs in Cardiovascular Biology and Disease

(2012) Akiko Hata   Annual Review of Physiology

MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: effect of statins on SIRT1 and microRNA-34a expression

(2012) Tsuyoshi Tabuchi et al.   CLINICAL SCIENCE

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

(2012) B. C. Bernardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Introduction to Murine Models of Atrial Fibrillation

(2012) Genna Riley et al.   Frontiers in Physiology

miR-34 – a microRNA replacement therapy is headed to the clinic

(2012) Andreas G. Bader   Frontiers in Genetics

A MicroRNA Guide for Clinicians and Basic Scientists: Background and Experimental Techniques

(2011) Bianca C. Bernardo et al.   Heart Lung and Circulation

Sex Differences in Cardiomyocyte Connexin43 Expression

(2011) Brian L Stauffer et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Silencing of microRNA families by seed-targeting tiny LNAs

(2011) Susanna Obad et al.   NATURE GENETICS

Putting gender on the agenda

(2010)   NATURE

Sex bias in trials and treatment must end

(2010) Alison M. Kim et al.   NATURE

Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies

(2010) Bianca C. Bernardo et al.   PHARMACOLOGY & THERAPEUTICS

Reduced Phosphoinositide 3-Kinase (p110α) Activation Increases the Susceptibility to Atrial Fibrillation

(2009) Lynette Pretorius et al.   AMERICAN JOURNAL OF PATHOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY