A New Potential Strategy for Treatment of Ischemic Stroke: Targeting TRPM2–NMDAR Association

Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury

(2022) Pengyu Zong et al.   NEURON

Floralozone improves cognitive impairment in vascular dementia rats via regulation of TRPM2 and NMDAR signaling pathway

(2022) Ya-ling Yin et al.   PHYSIOLOGY & BEHAVIOR

Neuronal Death Mechanisms and Therapeutic Strategy in Ischemic Stroke

(2022) Rui Mao et al.   Neuroscience Bulletin

Ischemic Stroke

(2021) Steven K. Feske   AMERICAN JOURNAL OF MEDICINE

Deficiency of ROS-Activated TRPM2 Channel Protects Neurons from Cerebral Ischemia-Reperfusion Injury through Upregulating Autophagy

(2021) Xupang Hu et al.   Oxidative Medicine and Cellular Longevity

Microglial NMDA receptors drive pro‐inflammatory responses via PARP‐1/TRMP2 signaling

(2020) Prajwal Raghunatha et al.   GLIA

TRPM7 Mediates Neuronal Cell Death Upstream of Calcium/Calmodulin-Dependent Protein Kinase II and Calcineurin Mechanism in Neonatal Hypoxic-Ischemic Brain Injury

(2020) Ekaterina Turlova et al.   Translational Stroke Research

Coupling of NMDA receptors and TRPM4 guides discovery of unconventional neuroprotectants

(2020) Jing Yan et al.   SCIENCE

Emerging neuroprotective strategies for the treatment of ischemic stroke: An overview of clinical and preclinical studies

(2020) Surojit Paul et al.   EXPERIMENTAL NEUROLOGY

Mechanistic study of TRPM2-Ca2+-CAMK2-BECN1 signaling in oxidative stress-induced autophagy inhibition

(2016) Qian Wang et al.   Autophagy

TRPM7 Regulates Axonal Outgrowth and Maturation of Primary Hippocampal Neurons

(2014) Ekaterina Turlova et al.   MOLECULAR NEUROBIOLOGY

TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia

(2014) M Ye et al.   Cell Death & Disease

Androgen and PARP-1 Regulation of TRPM2 Channels after Ischemic Injury

(2013) Takeru Shimizu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Modulation of NMDAR Subunit Expression by TRPM2 Channels Regulates Neuronal Vulnerability to Ischemic Cell Death

(2013) I. Alim et al.   JOURNAL OF NEUROSCIENCE

Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists

(2012) Thomas Papouin et al.   CELL

TRPM7 in cerebral ischemia and potential target for drug development in stroke

(2011) Christine You-jin Bae et al.   ACTA PHARMACOLOGICA SINICA