Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements

The Challenges in Developing Efficient and Robust Synthetic Homing Endonuclease Gene Drives

(2022) Sebald A. N. Verkuijl et al.   Frontiers in Bioengineering and Biotechnology

Toward a CRISPR-Cas9-Based Gene Drive in the Diamondback Moth Plutella xylostella

(2022) Xuejiao Xu et al.   CRISPR Journal

Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance

(2021) Andrew Hammond et al.   PLoS Genetics

High-resolution in situ analysis of Cas9 germline transcript distributions in gene-drive Anopheles mosquitoes

(2021) Gerard Terradas et al.   G3-Genes Genomes Genetics

A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment

(2020) Víctor López Del Amo et al.   Nature Communications

Development of a confinable gene drive system in the human disease vector Aedes aegypti

(2020) Ming Li et al.   eLife

Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed gRNAs

(2020) Samuel E. Champer et al.   Science Advances

Progress Toward Zygotic and Germline Gene Drives in Mice

(2020) Chandran Pfitzner et al.   CRISPR Journal

Opinion: Standardizing the definition of gene drive

(2020) Luke S. Alphey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes

(2019) Nikolay P. Kandul et al.   G3-Genes Genomes Genetics

Reducing resistance allele formation in CRISPR gene drive

(2018) Jackson Champer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes

(2018) Kyros Kyrou et al.   NATURE BIOTECHNOLOGY

Germline Cas9 expression yields highly efficient genome engineering in a major worldwide disease vector,Aedes aegypti

(2017) Ming Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations

(2017) Jackson Champer et al.   PLoS Genetics

Transmission potential of Zika virus infection in the South Pacific

(2016) Hiroshi Nishiura et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Estimate of the reproduction number of the 2015 Zika virus outbreak in Barranquilla, Colombia, and estimation of the relative role of sexual transmission

(2016) Sherry Towers et al.   Epidemics

Structure in the variability of the basic reproductive number (R0) for Zika epidemics in the Pacific islands

(2016) Clara Champagne et al.   eLife

A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

(2015) Andrew Hammond et al.   NATURE BIOTECHNOLOGY

Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquitoAnopheles stephensi

(2015) Valentino M. Gantz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estimating the basic reproduction number for single-strain dengue fever epidemics

(2014) Adnan Khan et al.   Infectious Diseases of Poverty

A Mathematical Model of Chikungunya Dynamics and Control: The Major Epidemic on Réunion Island

(2013) Laith Yakob et al.   PLoS One

Dengue disease, basic reproduction number and control

(2011) Helena Sofia Rodrigues et al.   INTERNATIONAL JOURNAL OF COMPUTER MATHEMATICS

Transcription Regulation of Sex-Biased Genes during Ontogeny in the Malaria Vector Anopheles gambiae

(2011) Kalle Magnusson et al.   PLoS One

The Risk of Chikungunya Fever in a Dengue‐Endemic Area

(2008) Eduardo Massad et al.   JOURNAL OF TRAVEL MEDICINE