期刊
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
卷 78, 期 5-6, 页码 235-246出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/znc-2022-0174
关键词
anti-inflammatory; antidiabetic; antioxidant; phytochemicals; solvents; tea
Different parts of Camellia sinensis (L.) were extracted using solvents of varying polarity to examine their phytochemical profiling and biological activities. The highest levels of total phenolic and flavonoid contents were observed in polar solvents, which also showed increased antioxidant, anti-inflammatory, and antidiabetic activities. HPTLC analysis revealed that polar solvents like hydroalcohol, methanol, and water yielded the highest levels of phenolic acids, epigallocatechin gallate, gallocatechin, and theaflavin, particularly in tea leaves. The findings suggested that polar solvents and young tea leaves were beneficial for obtaining extracts and that phenolics exhibited potent antioxidant, anti-inflammatory, and antidiabetic properties.
Different parts of Camellia sinensis (L.) were extracted with solvents according to polarity, and the extracts' phytochemical profiling and biological activities were examined. The total phenolic (TPC) and total flavonoid (TFC) contents increased with the increasing polarity of the solvent which met its maximum in polar solvents. The increasing antioxidant, anti-inflammatory and antidiabetic activities were recorded with increasing polarity of solvents which showed hydroalcoholic as best solvent. The strong and significant correlation was among the TPC, TFC, DPPH, anti-inflammatory and antidiabetic activities for different parts of tea. HPTLC study of individual phenolic acids, epigallocatechin gallate, gallocatechin and theaflavin met their maximum level of content with polar solvents like hydroalcohol, methanol and water mostly in mainly tea leaves. Our finding suggested that the polar solvents and young leaves of tea were beneficial for obtaining extracts. On the other hand, phenolics were found to be potent antioxidant, anti-inflammatory and antidiabetic agent.
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