Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1

Region-specific vulnerability in neurodegeneration: lessons from normal ageing

(2021) Virenkumar A. Pandya et al.   AGEING RESEARCH REVIEWS

Identification and characterization of conserved noncoding cis-regulatory elements that impact Mecp2 expression and neurological functions

(2021) Yingyao Shao et al.   GENES & DEVELOPMENT

Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome

(2020) Laura A Lavery et al.   eLife

Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation

(2020) Amanda M Brown et al.   eLife

Molecular layer interneurons shape the spike activity of cerebellar Purkinje cells

(2019) Amanda M. Brown et al.   Scientific Reports

Improved CUT&RUN chromatin profiling tools

(2019) Michael P Meers et al.   eLife

Cerebellar contribution to the cognitive alterations in SCA1: evidence from mouse models

(2019) Melissa Asher et al.   HUMAN MOLECULAR GENETICS

The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation

(2018) Simon Weissmann et al.   CANCER RESEARCH

Motor neuron degeneration correlates with respiratory dysfunction in SCA1

(2018) James P. Orengo et al.   Disease Models & Mechanisms

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism

(2018) Maxime W.C. Rousseaux et al.   NEURON

Loss of Atoh1 from neurons regulating hypoxic and hypercapnic chemoresponses causes neonatal respiratory failure in mice

(2018) Meike E van der Heijden et al.   eLife

gpGrouper: A Peptide Grouping Algorithm for Gene-Centric Inference and Quantitation of Bottom-Up Proteomics Data

(2018) Alexander B Saltzman et al.   MOLECULAR & CELLULAR PROTEOMICS

AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors

(2018) Hui Hu et al.   NUCLEIC ACIDS RESEARCH

Cistrome Data Browser: expanded datasets and new tools for gene regulatory analysis

(2018) Rongbin Zheng et al.   NUCLEIC ACIDS RESEARCH

Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans

(2017) Hsiang-Chih Lu et al.   NATURE GENETICS

An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites

(2017) Peter J Skene et al.   eLife

Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA

(2016) Christopher D Richardson et al.   NATURE BIOTECHNOLOGY

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

Pumilio1 Haploinsufficiency Leads to SCA1-like Neurodegeneration by Increasing Wild-Type Ataxin1 Levels

(2015) Vincenzo A. Gennarino et al.   CELL

In vivo analysis of Purkinje cell firing properties during postnatal mouse development

(2015) Marife Arancillo et al.   JOURNAL OF NEUROPHYSIOLOGY

Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain

(2015) Alisa Mo et al.   NEURON

The MEME Suite

(2015) Timothy L. Bailey et al.   NUCLEIC ACIDS RESEARCH

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Cerebellar Zonal Patterning Relies on Purkinje Cell Neurotransmission

(2014) J. J. White et al.   JOURNAL OF NEUROSCIENCE

A comparative encyclopedia of DNA elements in the mouse genome

(2014) Feng Yue et al.   NATURE

Generating genetically modified mice using CRISPR/Cas-mediated genome engineering

(2014) Hui Yang et al.   Nature Protocols

Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua

(2013) E. Kim et al.   GENES & DEVELOPMENT

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

(2013) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Development of the cerebellum: from gene expression patterns to circuit maps

(2012) Joshua J. White et al.   Wiley Interdisciplinary Reviews-Developmental Biology

MEME-ChIP: motif analysis of large DNA datasets

(2011) Philip Machanick et al.   BIOINFORMATICS

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Exercise and Genetic Rescue of SCA1 via the Transcriptional Repressor Capicua

(2011) J. D. Fryer et al.   SCIENCE

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: Hitting the Right Spot with Mesenchymal Stromal Cells

(2010) Jakub Tolar et al.   STEM CELLS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

A Novel POK Family Transcription Factor, ZBTB5, Represses Transcription ofp21CIP1Gene

(2009) Dong-In Koh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY