Programmable A-to-Y base editing by fusing an adenine base editor with an N-methylpurine DNA glycosylase

High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects

(2022) Huawei Tong et al.   NATURE BIOTECHNOLOGY

Programmable C:G to G:C genome editing with CRISPR-Cas9-directed base excision repair proteins

(2021) Liwei Chen et al.   Nature Communications

Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

(2021) Luke W. Koblan et al.   NATURE BIOTECHNOLOGY

Optimization of C-to-G base editors with sequence context preference predictable by machine learning methods

(2021) Tanglong Yuan et al.   Nature Communications

The base excision repair process: comparison between higher and lower eukaryotes

(2021) Nagham Nafiz Hindi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

(2020) Michelle F. Richter et al.   NATURE BIOTECHNOLOGY

New insights into abasic site repair and tolerance

(2020) Petria S. Thompson et al.   DNA REPAIR

CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells

(2020) Ibrahim C. Kurt et al.   NATURE BIOTECHNOLOGY

Glycosylase base editors enable C-to-A and C-to-G base changes

(2020) Dongdong Zhao et al.   NATURE BIOTECHNOLOGY

Base editing: advances and therapeutic opportunities

(2020) Elizabeth M. Porto et al.   NATURE REVIEWS DRUG DISCOVERY

CRISPResso2 provides accurate and rapid genome editing sequence analysis

(2019) Kendell Clement et al.   NATURE BIOTECHNOLOGY

Base editing: precision chemistry on the genome and transcriptome of living cells

(2018) Holly A. Rees et al.   NATURE REVIEWS GENETICS

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

(2017) Nicole M. Gaudelli et al.   NATURE

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

Translesion Synthesis across Abasic Lesions by Human B-Family and Y-Family DNA Polymerases α, δ, η, ι, κ, and REV1

(2010) Jeong-Yun Choi et al.   JOURNAL OF MOLECULAR BIOLOGY

DNA Repair in Mammalian Cells

(2009) A. B. Robertson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES