Ca2+-Sensitive Potassium Channels

Structural and Functional Coupling of Calcium-Activated BK Channels and Calcium-Permeable Channels Within Nanodomain Signaling Complexes

(2022) Kunal R. Shah et al.   Frontiers in Physiology

Channelopathy-causing mutations in the S45A/S45B and HA/HB helices of KCa2.3 and KCa3.1 channels alter their apparent Ca2+ sensitivity

(2022) Razan Orfali et al.   CELL CALCIUM

Syndromic disorders caused by gain-of-function variants in KCNH1, KCNK4, and KCNN3—a subgroup of K+ channelopathies

(2021) Karen W. Gripp et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Subtype‐selective positive modulation of K Ca 2 channels depends on the HA/HB helices

(2021) Young‐Woo Nam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Zimmermann–Laband syndrome in monozygotic twins with a mild neurobehavioral phenotype lacking gingival overgrowth—A case report of a novel KCNN3 gene variant

(2021) Martin Schwarz et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The Large-Conductance, Calcium-Activated Potassium Channel: A Big Key Regulator of Cell Physiology

(2021) Maria Sancho et al.   Frontiers in Physiology

SK Channels Modulation Accelerates Equilibrium Recovery in Unilateral Vestibular Neurectomized Rats

(2021) Brahim Tighilet et al.   Pharmaceuticals

LINGO1 is a regulatory subunit of large conductance, Ca2+-activated potassium channels

(2020) Srikanth Dudem et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heritable arrhythmias associated with abnormal function of cardiac potassium channels

(2020) Lia Crotti et al.   CARDIOVASCULAR RESEARCH

Hydrophobic interactions between the HA helix and S4‐S5 linker modulate apparent Ca 2+ sensitivity of SK2 channels

(2020) Young‐Woo Nam et al.   Acta Physiologica

Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders

(2020) Fanny Mochel et al.   BRAIN

Gardos channelopathy: functional analysis of a novel KCNN4 variant

(2020) Elisa Fermo et al.   Blood Advances

Gain-of-Function Mutations in KCNN3 Encoding the Small-Conductance Ca2+-Activated K+ Channel SK3 Cause Zimmermann-Laband Syndrome

(2019) Christiane K. Bauer et al.   AMERICAN JOURNAL OF HUMAN GENETICS

KCNMA1-linked channelopathy

(2019) Cole S. Bailey et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular determinants of Ca2+ sensitivity at the intersubunit interface of the BK channel gating ring

(2018) Qin Li et al.   Scientific Reports

A de novo mutation in KCNN3 associated with autosomal dominant idiopathic non-cirrhotic portal hypertension

(2016) Bart G.P. Koot et al.   JOURNAL OF HEPATOLOGY

Structural basis for gating the high-conductance Ca2+-activated K+ channel

(2016) Richard K. Hite et al.   NATURE

Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel

(2016) Xiao Tao et al.   NATURE

Mutations in the Gardos channel (KCNN4) are associated with hereditary xerocytosis

(2015) E. Glogowska et al.   BLOOD

Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome

(2015) Fanny Kortüm et al.   NATURE GENETICS

Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons

(2014) A M Dolga et al.   Cell Death & Disease

Clinical and genetic study of two patients with Zimmermann–Laband syndrome and literature review

(2013) Marco Castori et al.   European Journal of Medical Genetics

Function of BK Ca Channels Is Reduced in Human Vascular Smooth Muscle Cells From Han Chinese Patients With Hypertension

(2012) Yan Yang et al.   HYPERTENSION

Endothelial Small-Conductance and Intermediate-Conductance KCa Channels

(2012) Heike Wulff et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Ca2+-regulated ion channels

(2011) Daniel H. Cox   BMB Reports

A CAG repeat polymorphism ofKCNN3predicts SK3 channel function and cognitive performance in schizophrenia

(2011) Sabrina Grube et al.   EMBO Molecular Medicine

Membrane Trafficking of Large Conductance Calcium-activated Potassium Channels Is Regulated by Alternative Splicing of a Transplantable, Acidic Trafficking Motif in the RCK1-RCK2 Linker

(2010) Lie Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium

(2010) Jiusheng Yan et al.   NATURE

Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy

(2009) Liguo Wang et al.   NATURE

K+Channel Modulators for the Treatment of Neurological Disorders and Autoimmune Diseases

(2008) Heike Wulff et al.   CHEMICAL REVIEWS

Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a New Activator of KCa2 and KCa3.1 Potassium Channels, Potentiates the Endothelium-Derived Hyperpolarizing Factor Response and Lowers Blood Pressure

(2008) A. Sankaranarayanan et al.   MOLECULAR PHARMACOLOGY