The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination

Post-translational modification of MALT1 and its role in B cell- and T cell-related diseases

(2022) Yi-Yue Zhang et al.   BIOCHEMICAL PHARMACOLOGY

EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3

(2022) Ziwen Pan et al.   Molecular Cancer

Large-scale discovery of novel neurodevelopmental disorder-related genes through a unified analysis of single-nucleotide and copy number variants

(2022) Kohei Hamanaka et al.   Genome Medicine

Caspofungin Suppresses Brain Cell Necroptosis in Ischemic Stroke Rats via Up-Regulation of Pellino3

(2021) Yi-Yue Zhang et al.   CARDIOVASCULAR DRUGS AND THERAPY

MALT1 positively correlates with Th1 cells, Th17 cells, and their secreted cytokines and also relates to disease risk, severity, and prognosis of acute ischemic stroke

(2021) Xia Chen et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Dipsacoside B Exerts a Beneficial Effect on Brain Injury in the Ischemic Stroke Rat through Inhibition of Mitochondrial E3 Ubiquitin Ligase 1

(2021) Kai-Di Ren et al.   CNS & Neurological Disorders-Drug Targets

Src Family Kinases Inhibition Ameliorates Hypoxic-Ischemic Brain Injury in Immature Rats

(2021) Han Qiu et al.   Frontiers in Cellular Neuroscience

TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease

(2021) Thomas J. O’Neill et al.   Science Immunology

MALT1 Protease Plays a Dual Role in the Allergic Response by Acting in Both Mast Cells and Endothelial Cells

(2020) Danielle N. Alfano et al.   JOURNAL OF IMMUNOLOGY

Ubiquitination and functional modification of GluN2B subunit–containing NMDA receptors by Cbl-b in the spinal cord dorsal horn

(2020) Zi-Yang Zhang et al.   Science Signaling

NMDARs in Cell Survival and Death: Implications in Stroke Pathogenesis and Treatment

(2020) Yang Ge et al.   TRENDS IN MOLECULAR MEDICINE

GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis

(2020) Xichun Xia et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer

(2020) R. Vatapalli et al.   Nature Communications

The role of neurogenesis in neurorepair after ischemic stroke

(2019) Bruno L. Marques et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathway

(2019) Yi-Yue Zhang et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Mitochondrial E3 ubiquitin ligase 1 promotes brain injury by disturbing mitochondrial dynamics in a rat model of ischemic stroke

(2019) Kai-Di Ren et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells

(2019) Torben Gehring et al.   Cell Reports

Involvement of extrasynaptic glutamate in physiological and pathophysiological changes of neuronal excitability

(2018) Balázs Pál   CELLULAR AND MOLECULAR LIFE SCIENCES

Targeting NMDA receptors in stroke: new hope in neuroprotection

(2018) Qiu Jing Wu et al.   Molecular Brain

The receptor tyrosine kinase-like orphan receptor ROR2 modulates neuropathic pain via phosphorylation of N-methyl-D-aspartate receptor subunit GluN2B

(2018) X.L. Zhou et al.   BRITISH JOURNAL OF ANAESTHESIA

Mechanism of NMDA Receptor Inhibition and Activation

(2016) Shujia Zhu et al.   CELL

Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity

(2016) Nicholas L Weilinger et al.   NATURE NEUROSCIENCE

PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61

(2016) Sehoon Won et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting MALT1 Proteolytic Activity in Immunity, Inflammation and Disease: Good or Bad?

(2016) Annelies Demeyer et al.   TRENDS IN MOLECULAR MEDICINE

The paracaspase MALT1: biological function and potential for therapeutic inhibition

(2015) Maike Jaworski et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

STEP61is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease

(2015) Pradeep K. Kurup et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HECTD3 E3 Ubiquitin Ligase Suppresses Cisplatin-Induced Apoptosis via Stabilizing MALT1

(2015) Yi Li et al.   NEOPLASIA

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Does Na+/Ca2+ Exchanger, NCX, Represent a New Druggable Target in Stroke Intervention?

(2013) Giuseppe Pignataro et al.   Translational Stroke Research

Diversity in NMDA Receptor Composition

(2012) Antonio Sanz-Clemente et al.   NEUROSCIENTIST

Stroke intervention pathways: NMDA receptors and beyond

(2011) Ted Weita Lai et al.   TRENDS IN MOLECULAR MEDICINE

DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke

(2010) Weihong Tu et al.   CELL

A -Mediated NMDA Receptor Endocytosis in Alzheimer's Disease Involves Ubiquitination of the Tyrosine Phosphatase STEP61

(2010) P. Kurup et al.   JOURNAL OF NEUROSCIENCE

Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95

(2010) Li Zhou et al.   NATURE MEDICINE

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Differential requirement of MALT1 for BAFF-induced outcomes in B cell subsets

(2009) Michael W. Tusche et al.   JOURNAL OF EXPERIMENTAL MEDICINE