期刊
CELL
卷 160, 期 5, 页码 809-811出版社
CELL PRESS
DOI: 10.1016/j.cell.2015.02.007
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资金
- NIGMS NIH HHS [R01 GM055310, R37 GM051966] Funding Source: Medline
DNA recombinases face the daunting task of locating and pairing up specific sequences among millions of base pairs in a genome, all within about an hour. Qi et al. show that recombinases solve this problem by searching in 8-nt microhomology units, reducing the search space and accelerating the homology search.
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