Article
Geriatrics & Gerontology
Di Liu, Qin Zhang, Shasha Xing, Fang Wei, Ke Li, Yingxin Zhao, Hua Zhang, Gary Gong, Yuqi Guo, Zhendong Liu
Summary: Excessive salt intake has been found to accelerate the progression of cerebral small vessel disease (CSVD) in older adults, with the harmful effects increasing with higher intake levels.
Article
Nutrition & Dietetics
Tomonori Sugiura, Hiroyuki Takase, Nobuyuki Ohte, Yasuaki Dohi
Summary: The study found that salt intake increases with age in Japanese adults, which should be taken into consideration when devising strategies to lower salt intake.
NUTRITION RESEARCH
(2021)
Review
Medicine, General & Internal
E. M. Hodson, T. E. Cooper
Summary: This systematic review evaluates the effect of altered salt intake on blood pressure and cardiovascular markers in people with diabetes. The findings suggest that short-term salt restriction can significantly reduce both systolic and diastolic blood pressure in individuals with diabetes, similar to the effects of single-drug therapy for hypertension. These results support the international recommendations of reducing salt intake to less than 5 g/day (2 g sodium) for people with diabetes, regardless of hypertension or kidney disease.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2023)
Article
Nutrition & Dietetics
Aline Carare Candido, Sarah Aparecida Vieira Ribeiro, Mariana de Souza Macedo, Edimar Aparecida Filomeno Fontes, Eliana Carla Gomes De Souza, Maria Sonia Lopes Duarte, Silvia Eloiza Priore, Maria do Carmo Gouveia Peluzio, Regina Celia Rodrigues de Miranda Milagres, Sylvia do Carmo Castro Franceschini
Summary: According to the theoretical model, this study found that the daily iodine intake for schoolchildren and pregnant women in the region was excessive, emphasizing the importance of intervention planning.
FRONTIERS IN NUTRITION
(2021)
Article
Geriatrics & Gerontology
M. N. Wu, W. F. Liu, F. D. Li, Y. W. Huang, X. Gu, Y. J. Zhai, T. Zhang, L. Xu, Junfen Lin
Summary: This study investigates the association between iodized salt intake and cognitive function in older adults. The results indicate that iodized salt intake may reduce the risk of cognitive impairment in older adults living in coastal or inland areas, with a greater protective effect in coastal areas.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Urology & Nephrology
Robert W. Hunter, Neeraj Dhaun, Matthew A. Bailey
Summary: Salt intake is a biological necessity and plays a significant role in physiological systems, human societies, and global culture. However, excessive salt intake is associated with high blood pressure and is estimated to cause millions of deaths annually worldwide. Animal research has identified multiple mechanisms through which high salt intake contributes to diseases in various organs. Therapeutic interventions targeting these pathways are yet to be tested. Salt-reduction interventions have shown effectiveness in lowering blood pressure, but the hidden salt in processed foods poses a challenge to individual control. Implementing multi-component approaches involving government, education, and the food industry at the population level has been the most effective strategy for salt reduction.
NATURE REVIEWS NEPHROLOGY
(2022)
Article
Urology & Nephrology
Robert W. Hunter, Neeraj Dhaun, Matthew A. Bailey
Summary: Salt intake is a biological necessity that is deeply rooted in physiological systems, human societies, and global culture. However, excessive salt intake is associated with high blood pressure and is estimated to cause around 5 million deaths worldwide each year. Animal research has identified various mechanisms by which high salt intake contributes to diseases in different organ systems, but many of these pathways have not been tested for potential therapeutic interventions. Salt-reduction interventions can lower blood pressure, but the presence of "hidden" salt in processed foods makes it difficult for individuals to control their intake. In addition, growing inequalities in the food systems pose challenges to maintaining individual dietary control of salt intake. The most effective salt-reduction interventions have been implemented at the population level and involve multiple components, including government, education, and the food industry.
NATURE REVIEWS NEPHROLOGY
(2022)
Article
Endocrinology & Metabolism
Li Li, Yuwei Mi, Miao Xu, Liemin Ruan, Jie Sun, Qifa Song
Summary: Lowering dietary salt intake has multiple benefits for T2D treatment, including improving fasting blood glucose and glycated hemoglobin, reducing obesity, blood pressure, and visceral fat, as well as decreasing the prevalence of retinopathy and neuropathy.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Geriatrics & Gerontology
Lucia Camacho-Barcia, Jesus Garcia-Gavilan, Miguel angel Martinez-Gonzalez, Fernando Fernandez-Aranda, Serena Galie, Dolores Corella, Aida Cuenca-Royo, Dora Romaguera, Jesus Vioque, angel M. Alonso-Gomez, Julia Warnberg, J. Alfredo Martinez, Luis Serra-Majem, Ramon Estruch, M. Rosa Bernal-Lopez, Jose Lapetra, Xavier Pinto, Josep A. Tur, Antonio Garcia-Rios, Aurora Bueno-Cavanillas, Miguel Delgado-Rodriguez, Pilar Matia-Martin, Lidia Daimiel, Vicente Martin-Sanchez, Josep Vidal, Clotilde Vazquez, Emilio Ros, Miguel Ruiz Canela, Jose Sorli, Rafael De La Torre, Jadwiga Konieczna, Alejandro Oncina-Canovas, Lucas Tojal-Sierra, Jessica Perez-Lopez, Itziar Abete, Almudena Sanchez-Villegas, Rosa Casas, Araceli Munoz-Garach, Jose Manuel Santos-Lozano, Cristina Bouzas, Cristina Razquin, Raul Martinez-Lacruz, Olga Castaner, Aina M. Yanez, Rafael Valls-Enguix, Maria Concepcion Bello-Mora, Javier Basterra-Gortari, Josep Basora, Jordi Salas-Salvado, Monica Bullo
Summary: The study aimed to assess the association between dietary vitamin K intake changes and cognitive function. The results showed that an increase in dietary vitamin K intake was associated with better cognitive function scores.
Article
Geriatrics & Gerontology
Apisit Manacharoen, Kulapong Jayanama, Sirasa Ruangritchankul, Prin Vathesatogkit, Piyamitr Sritara, Daruneewan Warodomwichit
Summary: This study aimed to evaluate the association of body mass index (BMI) and dietary intake with the risk of mild cognitive impairment (MCI) and dementia. The results showed that obesity was associated with a greater risk of MCI, and low consumption of fresh red meat could be a risk factor for MCI and dementia. Further studies are needed to confirm and explain these findings.
Article
Neurosciences
Puja Agarwal, Christopher N. Ford, Sue E. Leurgans, Todd Beck, Pankaja Desai, Klodian Dhana, Denis A. Evans, Shannon Halloway, Thomas M. Holland, Kristin R. Krueger, Xiaoran Liu, Kumar Bharat Rajan, David A. Bennett
Summary: This study found that high sugar intake, especially from fructose and sucrose, is associated with an increased risk of dementia in older adults.
JOURNAL OF ALZHEIMERS DISEASE
(2023)
Article
Nutrition & Dietetics
Nurul Fatin Malek Rivan, Suzana Shahar, Nik Nur Izzati Nik Mohd Fakhruddin, Yee Xing You, Normah Che Din, Roslee Rajikan
Summary: Dietary patterns have a significant impact on cognitive function in older adults. The local snacks-fish and seafood-high salt foods diet increases the risk of mild cognitive impairment (MCI), while a higher intake of tropical fruits-oats diet can protect against dementia incidence.
FRONTIERS IN NUTRITION
(2022)
Article
Medicine, General & Internal
Hiroyuki Takase, Yuki Takeuchi, Tomotada Fujita, Tsuyoshi Ohishi
Summary: This study investigated the effects of dietary salt intake on bone density in the general female population, and found a significant negative association between salt intake and bone density. The study suggests that excessive salt intake independently reduces bone density in females. Therefore, osteoporosis can be prevented by reducing salt intake.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Review
Biochemistry & Molecular Biology
Kyoungjoo Cho
Summary: Cognitive impairment is a serious condition associated with aging and disruption of inflammation and innate immunity. Recent studies have shown that the innate immune system is prevalent in patients with Alzheimer's disease, and peripheral neutrophil markers can predict a decline in cognitive function in patients with mild cognitive impairment. Furthermore, altered levels of pro-inflammatory interleukins have been reported in patients with mild cognitive impairment, potentially playing a role in the progression from early cognitive impairment to dementia.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Physiology
Alex M. Barnett, Matthew C. Babcock, Joseph C. Watso, Kamila U. Migdal, Orlando M. Gutierrez, William B. Farquhar, Austin T. Robinson
Summary: Short-term high dietary salt intake can increase urinary excretion of the kidney injury biomarker NGAL in healthy young adults, without affecting blood pressure.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
(2022)