Discovery of Amphiphilic Xanthohumol Derivatives as Membrane-Targeting Antimicrobials against Methicillin-Resistant Staphylococcus aureus

Secondary Amine Pendant β-Peptide Polymers Displaying Potent Antibacterial Activity and Promising Therapeutic Potential in Treating MRSA-Induced Wound Infections and Keratitis

(2022) Yuxin Qian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design and Synthesis of Phenyl Sulfide-Based Cationic Amphiphiles as Membrane-Targeting Antimicrobial Agents against Gram-Positive Pathogens

(2022) Wanxin Liang et al.   Journal of Medicinal Chemistry

Triphenyl-sesquineolignan analogues derived from Illicium simonsii Maxim exhibit potent antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) by disrupting bacterial membranes

(2021) Yong Guo et al.   BIOORGANIC CHEMISTRY

Modular Design of Membrane-Active Antibiotics: From Macromolecular Antimicrobials to Small Scorpionlike Peptidomimetics

(2021) Minghui Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tomorrow’s biggest microbial threats

(2021) Mike May   NATURE MEDICINE

Strong Antimicrobial Effects of Xanthohumol and Beta-Acids from Hops against Clostridioides difficile Infection In Vivo

(2021) Radek Sleha et al.   Antibiotics-Basel

Development of Membrane-Active Honokiol/Magnolol Amphiphiles as Potent Antibacterial Agents against Methicillin-Resistant Staphylococcus aureus (MRSA)

(2021) Yong Guo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Natural Berberine-derived Azolyl Ethanols as New Structural Antibacterial Agents against Drug-Resistant Escherichia coli

(2021) Hang Sun et al.   JOURNAL OF MEDICINAL CHEMISTRY

Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses

(2021) Judith M. White et al.   mBio

Water Insensitive Synthesis of Poly-β-Peptides with Defined Architecture

(2020) Min Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Poly(2-Oxazoline) Based Functional Mimics of Peptides to Eradicate MRSA Infections and Persisters While Alleviating Antimicrobial Resistance

(2020) Min Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aquaculture at the crossroads of global warming and antimicrobial resistance

(2020) Miriam Reverter et al.   Nature Communications

The value of antimicrobial peptides in the age of resistance

(2020) Maria Magana et al.   LANCET INFECTIOUS DISEASES

Discovery, synthesis and biological evaluation of dunnianol-based Mannich bases against methicillin-resistant Staphylococcus aureus (MRSA)

(2020) Yong Guo et al.   ACS Infectious Diseases

Antimicrobial resistance: more than 70 years of war between humans and bacteria

(2020) Syeda Fatima Nadeem et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Phenolic Compounds from Humulus lupulus as Natural Antimicrobial Products: New Weapons in the Fight against Methicillin Resistant Staphylococcus aureus, Leishmania mexicana and Trypanosoma brucei Strains

(2019) Laetitia Bocquet et al.   MOLECULES

Anti-PqsR compounds as next-generation antibacterial agents against Pseudomonas aeruginosa: A review

(2019) Vahid Soheili et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Post-stress bacterial cell death mediated by reactive oxygen species

(2019) Yuzhi Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and synthesis of new norfloxacin-1,3,4-oxadiazole hybrids as antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA)

(2019) Yong Guo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Antibiotic development — economic, regulatory and societal challenges

(2019) Christine Årdal et al.   NATURE REVIEWS MICROBIOLOGY

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

Methicillin-resistant Staphylococcus aureus

(2018) Andie S. Lee et al.   Nature Reviews Disease Primers

Antimicrobial Properties of Spent Hops Extracts, Flavonoids Isolated Therefrom, and Their Derivatives

(2018) Agnieszka Bartmańska et al.   MOLECULES

Opportunities for natural products in 21st century antibiotic discovery

(2017) Gerard D. Wright   NATURAL PRODUCT REPORTS

A sensitive fluorescent sensor for the detection of endogenous hydroxyl radicals in living cells and bacteria and direct imaging with respect to its ecotoxicity in living zebra fish

(2016) Fei Liu et al.   CHEMICAL COMMUNICATIONS

Natural Products as a Source for Novel Antibiotics

(2016) Mark G. Moloney   TRENDS IN PHARMACOLOGICAL SCIENCES

Antiadherent and Antibiofilm Activity ofHumulus lupulusL. Derived Products: New Pharmacological Properties

(2013) Marcin Rozalski et al.   Biomed Research International

Beyond natural antimicrobial peptides: multimeric peptides and other peptidomimetic approaches

(2011) Andrea Giuliani et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Designing antimicrobial peptides: form follows function

(2011) Christopher D. Fjell et al.   NATURE REVIEWS DRUG DISCOVERY

Synergy Testing by Etest, Microdilution Checkerboard, and Time-Kill Methods for Pan-Drug-Resistant Acinetobacter baumannii

(2010) M. M. Sopirala et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY