Zhachong Shisanwei Pill resists ischemic stroke by lysosome pathway based on proteomics and bioinformatics

Yeast cell death pathway requiring AP-3 vesicle trafficking leads to vacuole/lysosome membrane permeabilization

(2022) Zachary D. Stolp et al.   Cell Reports

Aconitine: A review of its pharmacokinetics, pharmacology, toxicology and detoxification

(2022) Yabin Gao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Role of lysosomes in physiological activities, diseases, and therapy

(2021) Ziqi Zhang et al.   Journal of Hematology & Oncology

Ischemic Stroke

(2021) Steven K. Feske   AMERICAN JOURNAL OF MEDICINE

Zoology, chemical composition, pharmacology, quality control and future perspective of Musk (Moschus): a review

(2021) Kai Liu et al.   Chinese Medicine

The lysosome as an imperative regulator of autophagy and cell death

(2021) Kewal Kumar Mahapatra et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

(2021) Valery L Feigin et al.   LANCET NEUROLOGY

Global Epidemiology of Stroke and Access to Acute Ischemic Stroke Interventions

(2021) Vasu Saini et al.   NEUROLOGY

Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity

(2021) Irene Riera-Tur et al.   Life Science Alliance

Musk Ketone Induces Neural Stem Cell Proliferation and Differentiation in Cerebral Ischemia via Activation of the PI3K/Akt Signaling Pathway

(2020) Zheyi Zhou et al.   NEUROSCIENCE

Autophagy triggers CTSD (cathepsin D) maturation and localization inside cells to promote apoptosis

(2020) Yu-Qin Di et al.   Autophagy

Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective

(2020) M. Iqbal Hossain et al.   Autophagy

Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke

(2020) Joan Montaner et al.   Nature Reviews Neurology

Fruits of Terminalia chebula Retz.: A review on traditional uses, bioactive chemical constituents and pharmacological activities

(2020) Manisha Nigam et al.   PHYTOTHERAPY RESEARCH

Stroke

(2020) Bruce C V Campbell et al.   LANCET

Autophagy as a modulator of cell death machinery

(2020) Masayuki Noguchi et al.   Cell Death & Disease

Natural compounds modulate the autophagy with potential implication of stroke

(2020) Anil Ahsan et al.   Acta Pharmaceutica Sinica B

Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications

(2019) Francesca Nazio et al.   CELL DEATH AND DIFFERENTIATION

Global brain inflammation in stroke

(2019) Kaibin Shi et al.   LANCET NEUROLOGY

Neuroprotection by Luteolin and Gallic acid against cobalt chloride-induced behavioural, morphological and neurochemical alterations in Wistar rats

(2019) A.S. Akinrinde et al.   NEUROTOXICOLOGY

Bioinformatics-assisted, integrated omics studies on medicinal plants

(2019) Xiaoxia Ma et al.   BRIEFINGS IN BIOINFORMATICS

Lysosomes as dynamic regulators of cell and organismal homeostasis

(2019) Andrea Ballabio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export

(2019) Saskia Heybrock et al.   Nature Communications

Improved Neuroprotective Effects of Gallic Acid-Loaded Chitosan Nanoparticles Against Ischemic Stroke

(2019) Yongmei Zhao et al.   REJUVENATION RESEARCH

Lysosomal membrane permeabilization and cell death

(2018) Fengjuan Wang et al.   TRAFFIC

Neuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia

(2018) Yueyang Liu et al.   Autophagy

Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration

(2018) Paola Rusmini et al.   Autophagy

Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies

(2017) Karen S. Conrad et al.   Nature Communications

Brain Disorders Due to Lysosomal Dysfunction

(2016) Alessandro Fraldi et al.   Annual Review of Neuroscience

LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease

(2015) Michelle Rothaug et al.   Acta Neuropathologica Communications

LAMP-2: A control step for phagosome and autophagosome maturation

(2014) Paul Saftig et al.   Autophagy

Terminalia arjuna in coronary artery disease: Ethnopharmacology, pre-clinical, clinical & safety evaluation

(2014) Divya Kapoor et al.   JOURNAL OF ETHNOPHARMACOLOGY

Beta-asarone, a major component of Acorus tatarinowii Schott, attenuates focal cerebral ischemia induced by middle cerebral artery occlusion in rats

(2013) Yuan-Xiao Yang et al.   BMC Complementary and Alternative Medicine

Modern bioinformatics meets traditional Chinese medicine

(2013) P. Gu et al.   BRIEFINGS IN BIOINFORMATICS

Lysosomal integral membrane protein-2: A new player in lysosome-related pathology

(2013) Ashley Gonzalez et al.   MOLECULAR GENETICS AND METABOLISM

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Evidence of an association between the scavenger receptor class B member 2 gene and Parkinson's disease

(2012) Helen Michelakakis et al.   MOVEMENT DISORDERS

Lysosomal positioning coordinates cellular nutrient responses

(2011) Viktor I. Korolchuk et al.   NATURE CELL BIOLOGY

Autophagy was activated in injured astrocytes and mildly decreased cell survival following glucose and oxygen deprivation and focal cerebral ischemia

(2010) Ai-Ping Qin et al.   Autophagy

Hermansky-Pudlak Protein Complexes, AP-3 and BLOC-1, Differentially Regulate Presynaptic Composition in the Striatum and Hippocampus

(2010) K. Newell-Litwa et al.   JOURNAL OF NEUROSCIENCE

The role of lysosomal rupture in neuronal death

(2009) Tetsumori Yamashima et al.   PROGRESS IN NEUROBIOLOGY

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology

Mechanisms of lysosomal proteases participating in cerebral ischemia-induced neuronal death

(2008) Ai-Ping Qin et al.   Neuroscience Bulletin